Blocking viral entry with bulevirtide reduces the number of HDV-infected hepatocytes in human liver biopsies
Allweiss L, Volmari A, Suri V, Wallin J, Flaherty J, Manuilov D, Downie B, Lütgehetmann M, Bockmann J, Urban S, Wedemeyer H, Dandri M
J HEPATOL. 2024;80(6):882-891.

Molecular insights into the dynamic modulation of bacterial ClpP function and oligomerization by peptidomimetic boronate compounds
Alves França B, Falke S, Rohde H, Betzel C
SCI REP-UK. 2024;14(1):2572.

Pharmacokinetic/pharmacodynamic evaluation of tigecycline dosing in a hollow fiber infection model against clinical bla-KPC producing Klebsiella Pneumoniae isolates
Amann L, Broeker A, Riedner M, Rohde H, Huang J, Nordmann P, Decousser J, Wicha S
DIAGN MICR INFEC DIS. 2024;108(2):116153.

A multicenter evaluation of a novel microfluidic rapid AST assay for Gram-negative bloodstream infections
Berinson B, Davies E, Torpner J, Flinkfeldt L, Fernberg J, Åman A, Bergqvist J, Öhrn H, Ångström J, Johansson C, Jäder K, Andersson H, Ghaderi E, Rolf M, Sundqvist M, Rohde H, Fernandez-Zafra T, Malmberg C
J CLIN MICROBIOL. 2024;62(10):e0045824.

Influenza in travelers from Germany returning from abroad: a retrospective case-control study
Brehm T, Shijaku F, Krumkamp R, Jochum J, Hoffmann A, Ramharter M, Kreuels B
BMC INFECT DIS. 2024;24(1):1107.

High Genetic Diversity in Third-Generation Cephalosporin-Resistant Escherichia coli in Wastewater Systems of Schleswig-Holstein
Carlsen L, Grottker M, Heim M, Knobling B, Schlauß S, Wellbrock K, Knobloch J
PATHOGENS. 2024;13(1):.

Präsenz und Persistenz Carbapenemase-produzierender Enterobacterales in Abwasser von Krankenhäusern
Carlsen L, Knobling B, Franke G, Niesen J, Knobloch J
Hygiene & Medizin. 2024;49(11):D72-D79.

The added value of (1,3)-β-D-glucan for the diagnosis of Invasive Candidiasis in ICU patients: a prospective cohort study
Christner M, Abdennadher B, Wichmann D, Kluge S, Pepić A, Aepfelbacher M, Rohde H, Olearo F
INFECTION. 2024;52(1):73-81.

BCMA x CD3 T-cell engager in a patient with penta-refractory multiple myeloma and HIV: a clinical and immunological report
Cords L, Schaefers C, Kamili A, Hoffmann C, Cichutek S, Haag F, Polywka S, Bokemeyer C, Leypoldt L, Alsdorf W, Schulze zur Wiesch J, Weisel K
HAEMATOLOGICA. 2024;109(9):3071-3077.

Analysing carbapenemases in hospital wastewater:Insights from intracellular and extracellular DNA using qPCR and digital PCR
Erler T, Droop F, Lübbert C, Knobloch J, Carlsen L, Papan C, Schwanz T, Zweigner J, Dengler J, Hoffmann M, Mutters N, Savin M
SCI TOTAL ENVIRON. 2024;950:175344.

Adaptation and validation of a quantitative vanA/vanB DNA screening assay on a high-throughput PCR system
Giersch K, Tanida K, Both A, Nörz D, Heim D, Rohde H, Aepfelbacher M, Lütgehetmann M
SCI REP-UK. 2024;14(1):3523.

Staphylococcus epidermidis ST2 strains associated with bloodstream infections contain a unique mobile genetic element encoding a plasmin inhibitor
Gomez A, Kjerfve C, Choi M, Liu W, Churion K, Thomas S, Rohde H, Shelburne S, Skare J, Hook M, Arora S
MBIO. 2024 [Epub ahead of print];e0190724.

Immunity against measles, mumps, rubella, and varicella among homeless individuals in Germany - A nationwide multi-center cross-sectional study
Graf W, Bertram F, Dost K, Brennecke A, Kowalski V, van Rüth V, Nörz D, Wulff B, Ondruschka B, Püschel K, Pfefferle S, Lütgehetmann M, Heinrich F
FRONT PUBLIC HEALTH. 2024;12:1375151.

A multicenter study of asymmetric and symmetric dimethylarginine as predictors of mortality risk in hospitalized COVID-19 patients
Hannemann J, Zink A, Mileva Y, Balfanz P, Dahl E, Volland S, Illig T, Schwedhelm E, Kurth F, Stege A, Aepfelbacher M, Hoffmann A, Böger R
SCI REP-UK. 2024;14(1):15739.

Matrix metalloproteinases at a glance
Hey S, Linder S
J CELL SCI. 2024;137(2):.

Multiresistente Erreger – Sind sie auch resistent gegenüber Desinfektionsmitteln?
Knobloch J, Knobling B
DEUT MED WOCHENSCHR. 2024;149(19):1151-1157.

Delayed Induction of Noninflammatory SARS-CoV-2 Spike-Specific IgG4 Antibodies Detected 1 Year After BNT162b2 Vaccination in Children
Kobbe R, Rau C, Schulze-Sturm U, Stahl F, Fonseca-Brito L, Diemert A, Lütgehetmann M, Addo M, Arck P, Weskamm L
PEDIATR INFECT DIS J. 2024 [Epub ahead of print];43(12):1200-3.

Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages
Liebold I, Al Jawazneh A, Casar C, Lanzloth C, Leyk S, Hamley M, Wong M, Kylies D, Gräfe S, Edenhofer I, Aranda-Pardos I, Kriwet M, Haas H, Krause J, Hadjilaou A, Schromm A, Richardt U, Eggert P, Tappe D, Weidemann S, Ghosh S, Krebs C, A-Gonzalez N, Worthmann A, Lohse A, Huber S, Rothlin C, Puelles V, Jacobs T, Gagliani N, Bosurgi L
SCIENCE. 2024;384(6691):eabo7027.

Multicenter benchmarking of short and long read wet lab protocols for clinical viral metagenomics
Lopez-Labrador F, Huber M, Sidorov I, Brown J, Cuypers L, Laenen L, Vanmechelen B, Maes P, Fischer N, Pichler I, Storey N, Atkinson L, Schmutz S, Kufner V, van Boheemen S, Mulders C, Grundhoff A, Blümke P, Robitaille A, Cinek O, Hubáčková K, Mourik K, Boers S, Stauber L, Salmona M, Cappy P, Ramette A, Franze' A, LeGoff J, Claas E, Rodriguez C, de Vries J
J CLIN VIROL. 2024;173:105695.

Obesity and diabetes mellitus are associated with SARS-CoV-2 outcomes without influencing signature genes of extrapulmonary immune compartments at the RNA level
Lücke J, Böttcher M, Nawrocki M, Meins N, Schnell J, Heinrich F, Bertram F, Sabihi M, Seeger P, Pfaff M, Notz S, Blankenburg T, Zhang T, Kempski J, Reeh M, Wolter S, Mann O, Lütgehetmann M, Hackert T, Izbicki J, Duprée A, Huber S, Ondruschka B, Giannou A
HELIYON. 2024;10(2):e24508.

Inefficient tissue immune response against MPXV in an immunocompromised mpox patient
Matschke J, Hartmann K, Pfefferle S, Wang Y, Valdes P, Thies E, Schweizer M, Lütgehetmann M, Schmiedel S, Bernreuther C, Boyden E, Glatzel M, Krasemann S
J MED VIROL. 2024;96(7):e29811.

Development of Fragment-Based Inhibitors of the Bacterial Deacetylase LpxC with Low Nanomolar Activity
Mielniczuk S, Hoff K, Baselious F, Li Y, Haupenthal J, Kany A, Riedner M, Rohde H, Rox K, Hirsch A, Krimm I, Sippl W, Holl R
J MED CHEM. 2024;67(19):17363-17391.

Immune responses and clinical outcomes after COVID-19 vaccination in patients with liver disease and liver transplant recipients
Murray S, Pose E, Wittner M, Londoño M, Schaub G, Cook J, Dimitriadis S, Meacham G, Irwin S, Lim Z, Duengelhoef P, Sterneck M, Lohse A, Perez V, Trivedi P, Bhandal K, Mullish B, Manousou P, Provine N, Avitabile E, Carroll M, Tipton T, Healy S, Burra P, Klenerman P, Dunachie S, Kronsteiner B, Maciola A, Pasqual G, Hernandez-Gea V, Garcia-Pagan J, Lampertico P, Iavarone M, Gines P, Lütgehetmann M, Schulze Zur Wiesch J, Russo F, Barnes E, Marjot T
J HEPATOL. 2024;80(1):109-123.

Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling
Ohnezeit D, Huang J, Westerkamp U, Brinschwitz V, Schmidt C, Günther T, Czech-Sioli M, Weißelberg S, Schlemeyer T, Nakel J, Mai J, Schreiner S, Schneider C, Friedel C, Schwanke H, Brinkmann M, Grundhoff A, Fischer N
PLOS PATHOG. 2024;20(8):.

Revisiting diagnostics: Microbial cell free DNA-sequencing: addressing unmet challenges in implant-related cardiovascular Infections
Olearo F, Christner M, Lütgehetmann M, Aepfelbacher M, Fischer N, Rohde H
CLIN MICROBIOL INFEC. 2024 [Epub ahead of print].

Therapie bei MDR-, prä-XDR-, XDR-Tuberkulose und Rifampicin-Resistenz oder bei Medikamentenunverträglichkeit gegenüber mindestens Rifampicin: Amendment vom 19.09.2023 zur S2k-Leitlinie: Tuberkulose im Erwachsenenalter des Deutschen Zentralkomitees zur Bekämpfung der Tuberkulose e. V. (DZK) im Auftrag der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V. (DGP)
Otto-Knapp R, Bauer T, Brinkmann F, Feiterna-Sperling C, Friesen I, Geerdes-Fenge H, Hartmann P, Häcker B, Hauer B, Haas W, Heyckendorf J, Kuhns M, Lange C, Maurer F, Nienhaus A, Priwitzer M, Richter E, Salzer H, Schoch O, Schönfeld N, Schaberg T
PNEUMOLOGIE. 2024;78(1):35-46.

Treatment of MDR, Pre-XDR, XDR, and Rifampicin-Resistant Tuberculosis or in Case of Intolerance to at Least Rifampicin in Austria, Germany, and Switzerland
Otto-Knapp R, Bauer T, Brinkmann F, Feiterna-Sperling C, Friesen I, Geerdes-Fenge H, Hartmann P, Häcker B, Heyckendorf J, Kuhns M, Lange C, Maurer F, Nienhaus A, Priwitzer M, Richter E, Salzer H, Schoch O, Schönfeld N, Schaberg T
RESPIRATION. 2024;103(9):593-600.

Analytical and clinical validation of a multiplex PCR assay for detection of Neisseria gonorrhoeae and Chlamydia trachomatis including simultaneous LGV serotyping on an automated high-throughput PCR system
Pflüger L, Nörz D, Grunwald M, Pfefferle S, Giersch K, Christner M, Weber B, Aepfelbacher M, Rohde H, Lütgehetmann M
MICROBIOL SPECTR. 2024;12(3):e0275623.

Method for Quantitative HDV RNA Detection: I, Manual Workflow (Serum and Liver Tissue) and II, Fully Automated High Throughput Workflow for Diagnostic Use
Pflüger L, Volz T, Giersch K, Allweiss L, Dandri-Petersen M, Lütgehetmann M
Methods Mol Biol. 2024;2837:171-184.

Time-resolved crystallography of boric acid binding to the active site serine of the β-lactamase CTX-M-14 and subsequent 1,2-diol esterification
Prester A, Perbandt M, Galchenkova M, Oberthuer D, Werner N, Henkel A, Maracke J, Yefanov O, Hakanpää J, Pompidor G, Meyer J, Chapman H, Aepfelbacher M, Hinrichs W, Rohde H, Betzel C
COMMUN CHEM. 2024;7(1):152.

Effectiveness of high efficiency particulate (HEPA) air condition combined with the antifungal prophylaxis on incidence, morbidity and mortality of invasive fungal infections in patients with acute myeloid leukemia: a retrospective single-center study
Preyer L, Vettorazzi E, Fiedler W, Rohde H, Stemler J, Gönner S, Bokemeyer C, Khandanpour C, Wortmann F, Kebenko M
FRONT ONCOL. 2024;14:1429221.

Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor
Sake S, Zhang X, Rajak M, Urbanek-Quaing M, Carpentier A, Gunesch A, Grethe C, Matthaei A, Rückert J, Galloux M, Larcher T, Le Goffic R, Hontonnou F, Chatterjee A, Johnson K, Morwood K, Rox K, Elgaher W, Huang J, Wetzke M, Hansen G, Fischer N, Eléouët J, Rameix-Welti M, Hirsch A, Herold E, Empting M, Lauber C, Krey T, Haid S, Pietschmann T
NAT COMMUN. 2024;15(1):1173.

In vitro activity of cefiderocol against European Pseudomonas aeruginosa and Acinetobacter spp., including isolates resistant to meropenem and recent β-lactam/β-lactamase inhibitor combinations
Santerre Henriksen A, Jeannot K, Oliver A, Perry J, Pletz M, Stefani S, Morrissey I, Longshaw C
MICROBIOL SPECTR. 2024;12(4):.

Do asymptomatic STEC-long-term carriers need to be isolated or decolonized? New evidence from a community case study and concepts in favor of an individualized strategy
Sayk F, Hauswaldt S, Knobloch J, Rupp J, Nitschke M
FRONT PUBLIC HEALTH. 2024;12:1364664.

Concordance between MITS and conventional autopsies for pathological and virological diagnoses
Schädler J, Azeke A, Ondruschka B, Steurer S, Lütgehetmann M, Fitzek A, Möbius D
INT J LEGAL MED. 2024;138(2):431-442.

Pilot study in Hamburg on the prevalence of SARS-CoV-2 infections and pandemic survey in the German funeral industry
Schädler J, Lütgehetmann M, Schröder A, Edler C, Püschel K, Ondruschka B, Fitzek A
FORENSIC SCI MED PAT. 2024;20(2):500-507.

Gentamicin combination treatment is associated with lower mortality in patients with invasive listeriosis - a retrospective analysis
Sutter J, Kocheise L, Kempski J, Christner M, Wichmann D, Pinnschmidt H, Schmiedel S, Lohse A, Huber S, Brehm T
INFECTION. 2024;52(4):1601-1606.

Appeal from the European tuberculosis reference laboratory network (ERLTB-Net) for improving the diagnosis of infections due to nontuberculous mycobacteria
Tagliani E, Kohl T, Ghodousi A, Groenheit R, Holicka Y, Niemann S, Maurer F, Cirillo D, Cambau E
CLIN MICROBIOL INFEC. 2024;30(1):4-6.

Analytical and clinical validation of a novel, laboratory-developed, modular multiplex-PCR panel for fully automated high-throughput detection of 16 respiratory viruses
Tang H, Nörz D, Grunwald M, Giersch K, Pfefferle S, Fischer N, Aepfelbacher M, Rohde H, Lütgehetmann M
J CLIN VIROL. 2024;173:105693.

High vaccination coverage and infection rate result in a robust SARS-CoV-2-specific immunity in the majority of liver cirrhosis and transplant patients: A single-center cross-sectional study
von der Schulenburg P, Herting A, Harberts A, Lütgehetmann M, Jahnke-Triankowski J, Pischke S, Piecha F, Drolz A, Jörg V, Hübener P, Wehmeyer M, Addo M, Fischer L, Lohse A, Schulze Zur Wiesch J, Sterneck M
UNITED EUR GASTROENT. 2024;12(3):339-351.

Staphylococcus epidermidis alters macrophage polarization and phagocytic uptake by extracellular DNA release in vitro
Weißelberg S, Both A, Failla A, Huang J, Linder S, Ohnezeit D, Bartsch P, Aepfelbacher M, Rohde H
NPJ biofilms and microbiomes. 2024;10(1):131.

Population of invasive group A streptococci isolates from a German tertiary care center is dominated by the hypertoxigenic virulent M1UK genotype
Wolters M, Berinson B, Degel-Brossmann N, Hoffmann A, Bluszis R, Aepfelbacher M, Rohde H, Christner M
INFECTION. 2024;52(2):667-671.

HDV RNA Assays: Performance characteristics, clinical utility and challenges

HEPATOLOGY. 2023 [Epub ahead of print].

Cancer-Associated Fibroblasts Exert Proangiogenic Activity in Merkel Cell Carcinoma
Albertini S, Martuscelli L, Borgogna C, Virdi S, Indenbirken D, Lo Cigno I, Griffante G, Calati F, Boldorini R, Fischer N, Gariglio M
J INVEST DERMATOL. 2023;143(6):965-976.e15.

Stenotrophomonas maltophilia affects the gene expression profiles of the major pathogens Pseudomonas aeruginosa and Staphylococcus aureus in an in vitro multispecies biofilm model
Alio I, Moll R, Hoffmann T, Mamat U, Schaible U, Pappenfort K, Alawi M, Schie M, Thünauer R, Stamm J, Rohde H, Streit W
MICROBIOL SPECTR. 2023;11(6):.

Quantification of the hepatitis B virus cccDNA: evidence-based guidelines for monitoring the key obstacle of HBV cure
Allweiss L, Testoni B, Yu M, Lucifora J, Ko C, Qu B, Lütgehetmann M, Guo H, Urban S, Fletcher S, Protzer U, Levrero M, Zoulim F, Dandri-Petersen M
GUT. 2023;72(5):972-983.

CHROMAgar™ LIN-R as an efficient screening tool to assess the prevalence of linezolid-resistant enterococci in German hospital patients-a multicentre study approach, 2021-2022
Bender J, Baufeld E, Becker K, Claus H, Dudakova A, Dörre A, Fila N, Fleige C, Hamprecht A, Hoffmann A, Hogardt M, Kaasch A, Kola A, Kriebel N, Layer-Nicolaou F, Marschal M, Molitor E, Mutters N, Liese J, Nelkenbrecher C, Neumann B, Rohde H, Steinmann J, Sörensen M, Thelen P, Weig M, Zautner A, Werner G
J ANTIMICROB CHEMOTH. 2023;78(9):2185-2191.

Evaluation of a rapid combination disc test (RCDT) for direct phenotypic detection of extended-spectrum β-lactamase production in E. coli from positive blood culture bottles
Berinson B, Degel-Brossmann N, Olearo F, Roggenkamp H, Both A, Aepfelbacher M, Christner M, Rohde H
J ANTIMICROB CHEMOTH. 2023;78(4):1028-1033.

Performance and Hypothetical Impact on Joint Infection Management of the BioFire Joint Infection Panel: a Retrospective Analysis
Berinson B, Spenke L, Krivec L, Tanida K, Both A, Keller J, Rolvien T, Christner M, Lütgehetmann M, Aepfelbacher M, Klatte T, Rohde H
J CLIN MICROBIOL. 2023;61(8):.

A bacterial effector protein promotes nuclear translocation of Stat3 to induce IL-10.
Berneking L, Bekere I, Rob S, Schnapp M, Huang J, Ruckdeschel K, Aepfelbacher M
EUR J CELL BIOL. 2023;102(4):151364.

Complete genome sequence of a Staphylococcus condimenti isolated from a port catheter-associated bloodstream infection
Berneking L, Büttner H, Qi M, Günther T, Lehnhoff D, Both A, Christner M, Wolters M, Alawi M, Aepfelbacher M, Rohde H
MICROBIOL RESOUR ANN. 2023;12(10):.

Kidney-resident innate-like memory γδ T cells control chronic Staphylococcus aureus infection of mice
Bertram T, Reimers D, Lory N, Schmidt C, Schmid J, C Heinig L, Bradtke P, Rattay G, Zielinski S, Hellmig M, Bartsch P, Rohde H, Nuñez S, Rosemblatt M, Bono M, Gagliani N, Sandrock I, Panzer U, Krebs C, Meyer-Schwesinger C, Prinz I, Mittrücker H
P NATL ACAD SCI USA. 2023;120(1):e2210490120.

Comparison of the Diagnostic Accuracy of Three Real-Time PCR Assays for the Detection of Arcobacter butzleri in Human Stool Samples Targeting Different Genes in a Test Comparison without a Reference Standard
Binder R, Hahn A, Eberhardt K, Hagen R, Rohde H, Loderstädt U, Feldt T, Sarfo F, Di Cristanziano V, Kahlfuss S, Frickmann H, Zautner A
MICROORGANISMS. 2023;11(5):.

The added value of a commercial 16S/18S-PCR assay (UMD-SelectNA, Molzym) for microbiological diagnosis of spondylodiscitis:an observational study
Both A, Christner M, Berinson B, Dreimann M, Viezens L, Lütgehetmann M, Aepfelbacher M, Rohde H, Stangenberg M
DIAGN MICR INFEC DIS. 2023;106(1):.

Genomics of Invasive Cutibacterium acnes Isolates from Deep-Seated Infections
Both A, Huang J, Hentschke M, Tobys D, Christner M, Klatte T, Seifert H, Aepfelbacher M, Rohde H
MICROBIOL SPECTR. 2023;11(2):e0474022.

First case of bloodstream infection caused by Mixta hanseatica sp. nov., a novel species within the Mixta genus of the Erwiniaceae family
Both A, Huang J, Wenzel P, Aepfelbacher M, Rohde H, Christner M, Hentschke M
NEW MICROB NEW INFEC. 2023;53:101117.

Rapid Development of cefiderocol resistance in a carbapenem-resistant Pseudomonas aeruginosa isolate associated with mutations in the pyoverdine biosynthesis pathway
Brakert L, Berneking L, Both A, Berinson B, Huang J, Aepfelbacher M, Wolschke C, Wichmann D, Rohde H
J GLOB ANTIMICROB RE. 2023;34:59-62.

Comparative analysis of characteristics and outcomes in hospitalized COVID-19 patients infected with different SARS-CoV-2 variants between January 2020 and April 2022 - A retrospective single-center cohort study
Brehm T, Heyer A, Woo M, Fischer M, van der Meirschen M, Wichmann D, Jarczak D, Roedl K, Schmiedel S, Addo M, Lütgehetmann M, Christner M, Huber S, Lohse A, Kluge S, Schulze Zur Wiesch J
J INFECT PUBLIC HEAL. 2023;16(11):1806-1812.

Mini-laparoscopy as a diagnostic tool for abdominal tuberculosis: a retrospective series of 29 cases
Brehm T, Ndzedzeka-Völz N, Wehmeyer M, Christner M, Clauditz T, Hübener P, Addo M, Lohse A, Schmiedel S
SURG ENDOSC. 2023;37(3):1830-1837.

Long time persistence and evolution of carbapenemase-producing Enterobacterales in the wastewater of a tertiary care hospital in Germany
Carlsen L, Büttner H, Christner M, Cordts L, Franke G, Hoffmann A, Knobling B, Lütgehetmann M, Nakel J, Werner T, Knobloch J
J INFECT PUBLIC HEAL. 2023;16(8):1142-1148.

MINFLUX imaging of a bacterial molecular machine at nanometer resolution
Carsten A, Rudolph M, Weihs T, Schmidt R, Jansen I, Wurm C, Diepold A, Failla A, Wolters M, Aepfelbacher M
METHODS APPL FLUORES. 2023;11(1):.

Super-resolution fluorescence microscopy for investigating bacterial cell biology
Carsten A, Wolters M, Aepfelbacher M
MOL MICROBIOL. 2023 [Epub ahead of print].

Integration of Sequencing and Epidemiologic Data for Surveillance of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infections in a Tertiary-Care Hospital
Czech-Sioli M, Günther T, Robitaille A, Roggenkamp H, Büttner H, Indenbirken D, Christner M, Lütgehetmann M, Knobloch J, Aepfelbacher M, Grundhoff A, Fischer N
CLIN INFECT DIS. 2023;76(3):e263-e273.

Epidemiology of co-infections in pregnant women living with human immunodeficiency virus 1 in rural Gabon: a cross-sectional study
Davi S, Okwu D, Luetgehetmann M, Abba F, Aepfelbacher M, Endamne L, Alabi A, Zoleko-Manego R, Mombo-Ngoma G, Mahmoudou S, Addo M, Ramharter M, Mischlinger J
INFECT DIS POVERTY. 2023;12(1):.

Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement
Domínguez J, Boeree M, Cambau E, Chesov D, Conradie F, Cox V, Dheda K, Dudnyk A, Farhat M, Gagneux S, Grobusch M, Gröschel M, Guglielmetti L, Kontsevaya I, Lange B, van Leth F, Lienhardt C, Mandalakas A, Maurer F, Merker M, Miotto P, Molina-Moya B, Morel F, Niemann S, Veziris N, Whitelaw A, Horsburgh C, Lange C
LANCET INFECT DIS. 2023;23(4):e122-e137.

Long-Term Antibody Response to SARS-CoV-2 in Children
Dunay G, Barroso M, Woidy M, Danecka M, Engels G, Hermann K, Neumann F, Paul K, Beime J, Escherich G, Fehse K, Grinstein L, Haniel F, Haupt L, Hecher L, Kehl T, Kemen C, Kemper M, Kobbe R, Kohl A, Klokow T, Nörz D, Olfe J, Schlenker F, Schmiesing J, Schrum J, Sibbertsen F, Stock P, Tiede S, Vettorazzi E, Zazara D, Zapf A, Lütgehetmann M, Oh J, Mir T, Muntau A, Gersting S
J CLIN IMMUNOL. 2023;43(1):46-56.

Midgut Volvulus Adds a Murine, Neutrophil-Driven Model of Septic Condition to the Experimental Toolbox
Elrod J, Kiwit A, Lenz M, Rohde H, Börnigen D, Alawi M, Mohr C, Pagerols Raluy L, Trochimiuk M, Knopf J, Reinshagen K, Herrmann M, Boettcher M
CELLS-BASEL. 2023;12(3):.

Murine scald models characterize the role of neutrophils and neutrophil extracellular traps in severe burns
Elrod J, Lenz M, Kiwit A, Armbrust L, Schönfeld L, Reinshagen K, Pagerols Raluy L, Mohr C, Saygi C, Alawi M, Rohde H, Herrmann M, Boettcher M
FRONT IMMUNOL. 2023;14:1113948.

High burden of RSV and influenza in patients presenting with suspected pneumonia in the emergency room of a German tertiary hospital in fall of 2022
Ettemeyer M, Florey M, Tanida K, Jochum J, Schulze-Sturm U, Lütgehetmann M, Baehr M, Addo M, Schmiedel S, Rohde H, Koch T
INFECTION. 2023;51(5):1569-1575.

Performance of an interferon-γ release assay-based test for cell-mediated immunity to SARS-CoV-2
Fonseca B, Tödter S, Kottlau J, Cermann K, Spier A, Petersen E, Schäfer I, Twerenbold R, Aepfelbacher M, Lütgehetmann M, Stahl F
FRONT IMMUNOL. 2023;14:1069968.

Screening for Resistant Bacteria, Antimicrobial Resistance Genes, Sexually Transmitted Infections and Schistosoma spp. in Tissue Samples from Predominantly Vaginally Delivered Placentae in Ivory Coast and Ghana
Franz R, Hahn A, Hagen R, Rohde H, Eberhardt K, Ehrhardt S, Baum J, Claussen L, Feldt T, Hinz R, Barthel D, Bindt C, Tagbor H, Nguah S, Koffi M, Köller T, Warnke P, Pankok F, Taudien S, Frickmann H, Schoppen S
PATHOGENS. 2023;12(8):.

Towards clinical breakpoints for non-tuberculous mycobacteria - Determination of epidemiological cut off values for the Mycobacterium avium complex and Mycobacterium abscessus using broth microdilution
Fröberg G, Maurer F, Chryssanthou E, Fernström L, Benmansour H, Boarbi S, Mengshoel A, Keller P, Viveiros M, Machado D, Fitzgibbon M, Mok S, Werngren J, Cirillo D, Alcaide F, Hyyryläinen H, Aubry A, Andres S, Nadarajan D, Svensson E, Turnidge J, Giske C, Kahlmeter G, Cambau E, van Ingen J, Schön T
CLIN MICROBIOL INFEC. 2023;29(6):758-764.

Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo
Genduso S, Freytag V, Schetler D, Kirchner L, Schiecke A, Maar H, Wicklein D, Gebauer F, Bröker K, Stürken C, Milde-Langosch K, Oliveira-Ferrer L, Ricklefs F, Ewald F, Wolters-Eisfeld G, Riecken K, Unrau L, Krause L, Bohnenberger H, Offermann A, Perner S, Sebens S, Lamszus K, Diehl L, Linder S, Jücker M, Schumacher U, Lange T
J HEMATOL ONCOL. 2023;16(1):.

Strain-specific responsiveness of hepatitis D virus to interferon-alpha treatment
Giersch K, Perez-Gonzalez P, Hendricks L, Goldmann N, Kolbe J, Hermanussen L, Bockmann J, Volz T, Volmari A, Allweiss L, Petersen J, Glebe D, Lütgehetmann M, Dandri M
JHEP REP. 2023;5(4):100673.

Analysis of the humoral and cellular response after the third COVID-19 vaccination in patients with autoimmune hepatitis
Hartl J, Rüther D, Duengelhoef P, Brehm T, Steinmann S, Weltzsch J, Glaser F, Sterneck M, Sebode M, Weiler-Normann C, Lütgehetmann M, Schaub G, Haag F, Schramm C, Schulze Zur Wiesch J, Lohse A
LIVER INT. 2023;43(2):393-400.

New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany
Heinrich F, Huter T, Mertens S, Lange P, Vering J, Heinemann A, Nörz D, Hoffmann A, Aepfelbacher M, Ondruschka B, Krasemann S, Lütgehetmann M
EMERG INFECT DIS. 2023;29(3):652-656.

Tecovirimat for the treatment of severe Mpox in Germany
Hermanussen L, Brehm T, Wolf T, Boesecke C, Schlabe S, Borgans F, Monin M, Jensen B, Windhaber S, Scholten S, Jordan S, Lütgehetmann M, Wiesch J, Addo M, Mikolajewska A, Niebank M, Schmiedel S
INFECTION. 2023;51(5):1563-1568.

Tecovirimat therapy for severe monkeypox infection: Longitudinal assessment of viral titers and clinical response pattern-A first case-series experience
Hermanussen L, Grewe I, Tang H, Nörz D, Bal L, Pfefferle S, Unger S, Hoffmann C, Berzow D, Kohsar M, Aepfelbacher M, Lohse A, Addo M, Lütgehetmann M, Schulze zur Wiesch J, Schmiedel S
J MED VIROL. 2023;95(1):e28181.

Non-organ-specific autoantibodies with unspecific patterns are a frequent para-infectious feature of chronic hepatitis D
Hermanussen L, Lampalzer S, Bockmann J, Ziegler A, Piecha F, Dandri M, Pischke S, Haag F, Lohse A, Lütgehetmann M, Weiler-Normann C, Zur Wiesch J
FRONT MED-LAUSANNE. 2023;10:1169096.

Clinical Outcomes of SARS-CoV-2 Breakthrough Infections in Liver Transplant Recipients during the Omicron Wave
Herting A, Jahnke-Triankowski J, Harberts A, Schaub G, Lütgehetmann M, Ruether D, Fischer L, Addo M, Lohse A, Schulze Zur Wiesch J, Sterneck M
VIRUSES-BASEL. 2023;15(2):.

KIF16B drives MT1-MMP recycling in macrophages and promotes co-invasion of cancer cells
Hey S, Wiesner C, Barcelona B, Linder S
LIFE SCI ALLIANCE. 2023;6(11):.

Increased local bone turnover in patients with chronic periprosthetic joint infection
Hinz N, Butscheidt S, Jandl N, Rohde H, Keller J, Beil F, Hubert J, Rolvien T
BONE JOINT RES. 2023;12(10):644-653.

Activity of antimicrobial examination gloves under realistic conditions:challenge not fulfilled
Klupp E, Knobling B, Franke G, Belmar Campos C, Maurer P, Knobloch J
ANTIMICROB RESIST IN. 2023;12(1):.

Tolerance of clinical vancomycin-resistant Enterococcus faecium isolates against UV-C light from a mobile source
Knobling B, Franke G, Belmar Campos C, Büttner H, Christner M, Klupp E, Maurer P, Knobloch J
ANTIMICROB RESIST IN. 2023;12(1):.

Phenotypic Variation in Clinical S. aureus Isolates Did Not Affect Disinfection Efficacy Using Short-Term UV-C Radiation
Knobling B, Franke G, Carlsen L, Campos C, Büttner H, Klupp E, Maurer P, Knobloch J
MICROORGANISMS. 2023;11(5):.

Superiority of manual disinfection using pre-soaked wipes over automatic UV-C radiation without prior cleaning
Knobling B, Ulatowski A, Franke G, Belmar Campos C, Büttner H, Klupp E, Maurer P, Brill F, Knobloch J
J HOSP INFECT. 2023;140:72-78.

Was wir zur Effektivität von Masken wissen sollten
Knobloch J
Hamb Ärztebl. 2023;77(12):28-30.

Overview of tight fit and infection prevention benefits of respirators (filtering face pieces)
Knobloch J, Franke G, Knobloch M, Knobling B, Kampf G
J HOSP INFECT. 2023;134:89-96.

Maske, Luftfilter & Co: Brauchen wir Hygienekonzepte in Kitas und Schulen?
Knobloch J, Walger P
Hygiene & Medizin. 2023;48(7-8):D52-D59.

Infectious complications of radiologically placed upper arm ports:A single center analysis
Koehler D, Haus J, Shenas F, Rohde H, Ittrich H, Adam G, Peldschus K
PLOS ONE. 2023;18(4):e0284475.

Minimum inhibitory concentrations and sequencing data have to be analysed in more detail to set provisional epidemiological cut-off values for Mycobacterium tuberculosis complex
Köser C, Maurer F
EUR RESPIR J. 2023;61(5):.

Susceptibility of Multidrug-Resistant Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa from Germany to Ceftolozane-Tazobactam, Ceftazidime-Avibactam, and Imipenem-Relebactam
Kresken M, Wohlfarth E, Wichelhaus T, Gatermann S, Pfennigwerth N, Eisfeld J, Seifert H
MICROB DRUG RESIST. 2023;29(4):138-144.

Reduced Humoral and Cellular Immune Response to Primary COVID-19 mRNA Vaccination in Kidney Transplanted Children Aged 5–11 Years
Lalia J, Schild R, Lütgehetmann M, Dunay G, Kallinich T, Kobbe R, Massoud M, Oh J, Pietzsch L, Schulze-Sturm U, Schuetz C, Sibbertsen F, Speth F, Thieme S, Witkowski M, Berner R, Muntau A, Gersting S, Toepfner N, Pagel J, Paul K
VIRUSES-BASEL. 2023;15(7):1553.

Potent broadly neutralizing antibody VIR-3434 controls hepatitis B and D virus infection and reduces HBsAg in humanized mice
Lempp F, Volz T, Cameroni E, Benigni F, Zhou J, Rosen L, Noack J, Zatta F, Kaiser H, Bianchi S, Lombardo G, Jaconi S, Vincenzetti L, Imam H, Soriaga L, Passini N, Belnap D, Schulze A, Lütgehetmann M, Telenti A, Cathcart A, Snell G, Purcell L, Hebner C, Urban S, Dandri M, Corti D, Schmid M
J HEPATOL. 2023;79(5):1129-1138.

Get a grip: Podosomes as potential players in phagocytosis
Linder S, Barcelona B
EUR J CELL BIOL. 2023;102(4):.

Mechanisms and roles of podosomes and invadopodia
Linder S, Cervero P, Eddy R, Condeelis J
NAT REV MOL CELL BIO. 2023;24:86–106.

Intestinal IL-1β Plays a Role in Protecting against SARS-CoV-2 Infection
Lücke J, Heinrich F, Malsy J, Meins N, Schnell J, Böttcher M, Nawrocki M, Zhang T, Bertram F, Sabihi M, Kempski J, Blankenburg T, Duprée A, Reeh M, Wolter S, Mann O, Izbicki J, Lohse A, Gagliani N, Lütgehetmann M, Bunders M, Altfeld M, Sauter G, Giannou A, Krasemann S, Ondruschka B, Huber S
J IMMUNOL. 2023;211(6):1052-1061.

TNFα aggravates detrimental effects of SARS-CoV-2 infection in the liver
Lücke J, Nawrocki M, Schnell J, Meins N, Heinrich F, Zhang T, Bertram F, Sabihi M, Böttcher M, Blankenburg T, Pfaff M, Notz S, Kempski J, Reeh M, Wolter S, Mann O, Izbicki J, Lütgehetmann M, Duprée A, Giannou A, Ondruschka B, Huber S
FRONT IMMUNOL. 2023;14:1151937.

Evaluation of a Quantitative Dual-Target EBV DNA Test on a Fully Automated Molecular Testing System
Lütgehetmann M, Albert E, Hamilton A, Jarem D, Pfefferle S, Stucki H, Navarro D
J CLIN MICROBIOL. 2023;61(8):.

Interlaboratory reproducibility of a touch-transfer assay for the assessment of antimicrobial surfaces
Mayr A, Knobloch J, Hinterberger G, Seewald V, Wille I, Kaltseis J, Knobling B, Klupp E, Samardzic E, Lass-Flörl C
J HOSP INFECT. 2023;134:1-6.

Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography
Mehrabi P, Sung S, von Stetten D, Prester A, Hatton C, Kleine-Döpke S, Berkes A, Gore G, Leimkohl J, Schikora H, Kollewe M, Rohde H, Wilmanns M, Tellkamp F, Schulz E
NAT COMMUN. 2023;14(1):2365.

SARS-CoV-2 Vaccination-Induced Immunogenicity in Heart Transplant Recipients
Memenga F, Kueppers S, Borof K, Kirchhof P, Duengelhoef P, Barten M, Lütgehetmann M, Berisha F, Fluschnik N, Becher P, Kondziella C, Bernhardt A, Reichenspurner H, Blankenberg S, Magnussen C, Rybczynski M
TRANSPL INT. 2023;36:10883.

The Impact of Antimicrobial Therapy Duration in the Treatment of Prosthetic Joint Infections Depending on Surgical Strategies:A Systematic Review and Meta-analysis
Olearo F, Zanichelli V, Exarchakou A, Both A, Uςkay I, Aepfelbacher M, Rohde H
OPEN FORUM INFECT DI. 2023;10(5):.

IKK1 aggravates ischemia-reperfusion kidney injury by promoting the differentiation of effector T cells
Song N, Xu Y, Paust H, Panzer U, Noriega M, Guo L, Renne T, Huang J, Meng X, Zhao M, Thaiss F
CELL MOL LIFE SCI. 2023;80(5):125.

Comparison of four commercial EBV DNA quantitative tests to a new test at an early stage of development
Stelzl E, Kessler H, Parulekar A, Bier C, Nörz D, Schneider T, Kumar S, Simon C, Lütgehetmann M
J CLIN VIROL. 2023;161:.

Novel Synergies and Isolate Specificities in the Drug Interaction Landscape of Mycobacterium abscessus
Van N, Degefu Y, Leus P, Larkins-Ford J, Klickstein J, Maurer F, Stone D, Poonawala H, Thorpe C, Smith T, Aldridge B
ANTIMICROB AGENTS CH. 2023;67(7):e00090-23.

MT1-MMP and ADAM10/17 exhibit a remarkable overlap of shedding properties
Werny L, Grogro A, Bickenbach K, Bülck C, Armbrust F, Koudelka T, Pathak K, Scharfenberg F, Sammel M, Sheikhouny F, Tholey A, Linder S, Becker-Pauly C
FEBS J. 2023;290(1):93-111.

Evidence for broad cross-reactivity of the SARS-CoV-2 NSP12-directed CD4+ T-cell response with pre-primed responses directed against common cold coronaviruses
Westphal T, Mader M, Karsten H, Cords L, Knapp M, Schulte S, Hermanussen L, Peine S, Ditt V, Grifoni A, Addo M, Huber S, Sette A, Lütgehetmann M, Pischke S, Kwok W, Sidney J, Schulze Zur Wiesch J
FRONT IMMUNOL. 2023;14:.

DNases improve effectiveness of antibiotic treatment in murine polymicrobial sepsis
Willemsen J, Wenskus J, Lenz M, Rhode H, Trochimiuk M, Appl B, Pagarol-Raluy L, Börnigen D, Bang C, Reinshagen K, Herrmann M, Elrod J, Boettcher M
FRONT IMMUNOL. 2023;14:1254838.

Synthesis, biological evaluation, and molecular docking studies of aldotetronic acid-based LpxC inhibitors
Wimmer S, Hoff K, Martin B, Grewer M, Denni L, Lascorz Massanet R, Raimondi M, Bülbül E, Melesina J, Hotop S, Haupenthal J, Rohde H, Heisig P, Hirsch A, Brönstrup M, Sippl W, Holl R
BIOORG CHEM. 2023;131:.

Proteolysis of CD44 at the cell surface controls a downstream protease network
Wöhner B, Li W, Hey S, Drobny A, Werny L, Becker-Pauly C, Lucius R, Zunke F, Linder S, Arnold P
FRONT MOL BIOSCI. 2023;10:.

Sotrovimab in Hospitalized Patients with SARS-CoV-2 Omicron Variant Infection: a Propensity Score-Matched Retrospective Cohort Study
Woo M, Brehm T, Fischer M, Heyer A, Wichmann D, Jordan S, Nörz D, Lütgehetmann M, Addo M, Lohse A, Schmiedel S, Kluge S, Schulze Zur Wiesch J
MICROBIOL SPECTR. 2023;11(1):.

Absence of self-reported neuropsychiatric and somatic symptoms after Omicron variant SARS-CoV-2 breakthrough infections
Woo M, Mayer C, Brehm T, Andersen G, Weigel A, Löwe B, Lohse A, Addo M, Gerloff C, Knobloch J, Schulze Zur Wiesch J, Friese M
BRAIN COMMUN. 2023;5(2):fcad092.

Vagus nerve inflammation contributes to dysautonomia in COVID-19
Woo M, Shafiq M, Fitzek A, Dottermusch M, Altmeppen H, Mohammadi B, Mayer C, Bal L, Raich L, Matschke J, Krasemann S, Pfefferle S, Brehm T, Lütgehetmann M, Schädler J, Addo M, Schulze Zur Wiesch J, Ondruschka B, Friese M, Glatzel M
ACTA NEUROPATHOL. 2023;146(3):387-394.

Infant immunity against viral infections is advanced by the placenta-dependent vertical transfer of maternal antibodies
Albrecht M, Pagenkemper M, Wiessner C, Spohn M, Lütgehetmann M, Jacobsen H, Gabriel G, Zazara-Giannou D, Haertel C, Hecher K, Diemert A, Arck P
VACCINE. 2022;40(11):1563-1571.

Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo
Allweiss L, Giersch K, Pirosu A, Volz T, Muench R, Beran R, Urban S, Javanbakht H, Fletcher S, Lütgehetmann M, Dandri-Petersen M
GUT. 2022;71(2):372-381.

Target capture sequencing reveals a monoclonal outbreak of respiratory syncytial virus B infections among adult hematologic patients
Baier C, Huang J, Reumann K, Indenbirken D, Thol F, Koenecke C, Ebadi E, Heim A, Bange F, Haid S, Pietschmann T, Fischer N
ANTIMICROB RESIST IN. 2022;11(1):88.

Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in Staphylococcus aureus infection
Bartsch P, Kilian C, Hellmig M, Paust H, Borchers A, Sivayoganathan A, Enk L, Zhao Y, Shaikh N, Büttner H, Wong M, Puelles V, Wiech T, Flavell R, Huber T, Turner J, Bonn S, Huber S, Gagliani N, Mittrücker H, Rohde H, Panzer U, Krebs C
PLOS PATHOG. 2022;18(4):e1010430.

The Transcription Factor SpoVG Is of Major Importance for Biofilm Formation of Staphylococcus epidermidis under In Vitro Conditions, but Dispensable for In Vivo Biofilm Formation
Benthien H, Fresenborg B, Pätzold L, Elhawy M, Huc-Brandt S, Beisswenger C, Krasteva-Christ G, Becker S, Molle V, Knobloch J, Bischoff M
INT J MOL SCI. 2022;23(6):.

Detection of human herpes virus 6 DNA and chromosomal integration after allogeneic hematopoietic stem cell transplantation: a retrospective single center analysis
Berneking L, Both A, Langebrake C, Aepfelbacher M, Lütgehetmann M, Kröger N, Christopeit M
TRANSPL INFECT DIS. 2022;24(3):e13836.

Evaluation of a syndromic panel polymerase chain reaction (spPCR) assay for the diagnosis of device associated bone and joint infections (BJI)
Berneking L, Haas M, Frielinghaus L, Berinson B, Lütgehetmann M, Christner M, Aepfelbacher M, Gerlach U, Seide K, Both A, Rohde H
INT J INFECT DIS. 2022;116:283-288.

Impact of single-room contact precautions on acquisition and transmission of vancomycin-resistant enterococci on haematological and oncological wards, multicentre cohort-study, Germany, January-December 2016
Biehl L, Higgins P, Stemler J, Gilles M, Peter S, Dörfel D, Vogel W, Kern W, Gölz H, Bertz H, Rohde H, Klupp E, Schafhausen P, Salmanton-García J, Stecher M, Wille J, Liss B, Xanthopoulou K, Zweigner J, Seifert H, Vehreschild M
EUROSURVEILLANCE. 2022;27(2):.

Mucha-Habermann disease: a pediatric case report and proposal of a risk score
Blohm M, Ebenebe C, Rau C, Escherich C, Johannsen J, Escherich G, Driemeyer J, Nagel P, Kobbe R, Lütgehetmann M, Lennartz M, Booken N, Schneider S, Singer D
INT J DERMATOL. 2022;61(4):401-409.

Markers of neutrophil activation and extracellular trap formation predict appendicitis
Boettcher M, Schacker A, Esser M, Schönfeld L, Ebenebe C, Rohde H, Mokhaberi N, Trochimiuk M, Appl B, Raluy L, Reinshagen K, Klohs S, Königs I
SURGERY. 2022;171(2):312-319.

Population dynamics in colonizing vancomycin-resistant Enterococcus faecium isolated from immunosuppressed patients
Both A, Kruse F, Mirwald N, Franke G, Christner M, Huang J, Hansen J, Kröger N, Berneking L, Lellek H, Aepfelbacher M, Rohde H
J GLOB ANTIMICROB RE. 2022;28:267-273.

Clinical efficacy and in vitro neutralization capacity of monoclonal antibodies for severe acute respiratory syndrome coronavirus 2 delta and omicron variants
Brehm T, Pfefferle S, von Possel R, Karolyi M, Zoufaly A, Wichmann D, Kobbe R, Emmerich P, Nörz D, Aepfelbacher M, Schulze Zur Wiesch J, Addo M, Schmiedel S, Lütgehetmann M
J MED VIROL. 2022;94(10):5038-5043.

Three Separate Spike Antigen Exposures by COVID-19 Vaccination or SARS-CoV-2 Infection Elicit Strong Humoral Immune Responses in Healthcare Workers
Brehm T, Ullrich F, Thompson M, Küchen J, Schwinge D, Spier A, Huber S, Knobloch J, Aepfelbacher M, Addo M, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
VACCINES-BASEL. 2022;10(7):.

Expanded Diversity and Host Range of Bovine Hepacivirus-Genomic and Serological Evidence in Domestic and Wild Ruminant Species
Breitfeld J, Fischer N, Tsachev I, Marutsov P, Baymakova M, Plhal R, Keuling O, Becher P, Baechlein C
VIRUSES-BASEL. 2022;14(7):.

High burden and diversity of carbapenemase-producing Enterobacterales observed in wastewater of a tertiary care hospital in Germany
Carlsen L, Büttner H, Christner M, Franke G, Indenbirken D, Knobling B, Lütgehetmann M, Knobloch J
INT J HYG ENVIR HEAL. 2022;242:.

Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19
Casagrande M, Fitzek A, Spitzer M, Püschel K, Glatzel M, Krasemann S, Aepfelbacher M, Nörz D, Lütgehetmann M, Pfefferle S, Spitzer M
BRIT J OPHTHALMOL. 2022;106(9):1313-1317.

Risk of transfusion-transmitted hepatitis E virus infection from pool-tested platelets and plasma
Cordes A, Goudeva L, Lütgehetmann M, Wenzel J, Behrendt P, Wedemeyer H, Heim A
J HEPATOL. 2022;76(1):46-52.

High and Sustained Ex Vivo Frequency but Altered Phenotype of SARS-CoV-2-Specific CD4+ T-Cells in an Anti-CD20-Treated Patient with Prolonged COVID-19
Cords L, Knapp M, Woost R, Schulte S, Kummer S, Ackermann C, Beisel C, Peine S, Johansson A, Kwok W, Günther T, Fischer N, Wittner M, Addo M, Huber S, Schulze Zur Wiesch J
VIRUSES-BASEL. 2022;14(6):.

The hepatitis delta virus and chronic hepatitis D
Dandri M, Volmari A, Lütgehetmann M
J HEPATOL. 2022;77(5):1448-1450.

SARS-CoV-2 vaccination response in patients with autoimmune hepatitis and autoimmune cholestatic liver disease
Duengelhoef P, Hartl J, Rüther D, Steinmann S, Brehm T, Weltzsch J, Glaser F, Schaub G, Sterneck M, Sebode M, Weiler-Normann C, Addo M, Lütgehetmann M, Haag F, Schramm C, Schulze Zur Wiesch J, Lohse A
UNITED EUR GASTROENT. 2022;10(3):319-329.

Clinical features of hepatitis E infections in patients with hematologic disorders
Ghandili S, Lindhauer C, Pischke S, Zur Wiesch J, Von Kroge P, Polywka S, Bokemeyer C, Fiedler W, Kröger N, Ayuk F, Adjallé R, Modemann F
HAEMATOLOGICA. 2022;107(12):2870-2883.

Diagnostic Utility of Bronchoalveolar Lavage in Patients with Acute Leukemia under Broad-Spectrum Anti-Infective Treatment
Ghandili S, von Kroge P, Simon M, Henes F, Rohde H, Hoffmann A, Lindeman N, Bokemeyer C, Fiedler W, Modemann F
CANCERS. 2022;14(11):.

Natural killer cell-mediated ADCC in SARS-CoV-2-infected individuals and vaccine recipients
Hagemann K, Riecken K, Jung J, Hildebrandt H, Menzel S, Bunders M, Fehse B, Koch-Nolte F, Heinrich F, Peine S, Schulze Zur Wiesch J, Brehm T, Addo M, Lütgehetmann M, Altfeld M
EUR J IMMUNOL. 2022;52(8):1297-1307.

Humoral and Cellular Immune Response After Third and Fourth SARS-CoV-2 mRNA Vaccination in Liver Transplant Recipients
Harberts A, Schaub G, Ruether D, Duengelhoef P, Brehm T, Karsten H, Fathi A, Jahnke-Triankowski J, Fischer L, Addo M, Haag F, Lütgehetmann M, Lohse A, Schulze zur Wiesch J, Sterneck M
CLIN GASTROENTEROL H. 2022;20(11):2558-2566.e5.

Correction: Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolved COVID-19
Heide J, Schulte S, Kohsar M, Brehm T, Herrmann M, Karsten H, Marget M, Peine S, Johansson A, Sette A, Lütgehetmann M, Kwok W, Sidney J, Schulze Zur Wiesch J
PLOS PATHOG. 2022;18(1):.

Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant
Heinrich F, Romich C, Zimmermann T, Kniep I, Fitzek A, Steurer S, Glatzel M, Nörz D, Günther T, Czech-Sioli M, Fischer N, Grundhoff A, Lütgehetmann M, Ondruschka B
INT J LEGAL MED. 2022;136(1):193-202.

Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2-Associated Deaths
Heinrich F, Schröder A, Gerberding A, Gerling M, Langenwalder F, Lange P, Heinemann A, Bibiza-Freiwald E, Nörz D, Aepfelbacher M, Pfefferle S, Ondruschka B, Lütgehetmann M
EMERG INFECT DIS. 2022;28(1):244-247.

Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection
Heyer A, Günther T, Robitaille A, Lütgehetmann M, Addo M, Jarczak D, Kluge S, Aepfelbacher M, Schulze Zur Wiesch J, Fischer N, Grundhoff A
CELL REP MED. 2022;3(9):.

There and back again: Intracellular trafficking, release and recycling of matrix metalloproteinases
Hey S, Ratt A, Linder S
BBA-MOL CELL RES. 2022;1869(4):.

Peptide microarrays coupled to machine learning reveal individual epitopes from human antibody responses with neutralizing capabilities against SARS-CoV-2
Hotop S, Reimering S, Shekhar A, Asgari E, Beutling U, Dahlke C, Fathi A, Khan F, Lütgehetmann M, Ballmann R, Gerstner A, Tegge W, Cicin-Sain L, Bilitewski U, McHardy A, Brönstrup M
EMERG MICROBES INFEC. 2022;11(1):1037-1048.

A pharmacokinetic-pharmacodynamic (PKPD) model-based analysis of tedizolid against enterococci using the hollow-fibre infection model
Iqbal K, Rohde H, Huang J, Tikiso T, Amann L, Zeitlinger M, Wicha S
J ANTIMICROB CHEMOTH. 2022;77(9):2470–2478.

Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?
Jonigk D, Werlein C, Acker T, Aepfelbacher M, Amann K, Baretton G, Barth P, Bohle R, Büttner A, Büttner R, Dettmeyer R, Eichhorn P, Elezkurtaj S, Esposito I, Evert K, Evert M, Fend F, Gaßler N, Gattenlöhner S, Glatzel M, Göbel H, Gradhand E, Hansen T, Hartmann A, Heinemann A, Heppner F, Hilsenbeck J, Horst D, Kamp J, Mall G, Märkl B, Ondruschka B, Pablik J, Pfefferle S, Quaas A, Radbruch H, Röcken C, Rosenwald A, Roth W, Rudelius M, Schirmacher P, Slotta-Huspenina J, Smith K, Sommer L, Stock K, Ströbel P, Strobl S, Titze U, Weirich G, Weis J, Werner M, Wickenhauser C, Wiech T, Wild P, Welte T, von Stillfried S, Boor P
VIRCHOWS ARCH. 2022;481(2):139-159.

High-resolution analysis of individual spike peptide-specific CD4+ T-cell responses in vaccine recipients and COVID-19 patients
Karsten H, Cords L, Westphal T, Knapp M, Brehm T, Hermanussen L, Omansen T, Schmiedel S, Woost R, Ditt V, Peine S, Lütgehetmann M, Huber S, Ackermann C, Wittner M, Addo M, Sette A, Sidney J, Schulze Zur Wiesch J
CLIN TRANSL IMMUNOL. 2022;11(8):.

Mechanisms of CD8+ T cell failure in chronic hepatitis E virus infection
Kemming J, Gundlach S, Panning M, Huzly D, Huang J, Lütgehetmann M, Fischer N, Neumann-Haefelin C
J HEPATOL. 2022;77(4):978-990.

The giant staphylococcal protein Embp facilitates colonization of surfaces through Velcro-like attachment to fibrillated fibronectin
Khan N, Aslan H, Büttner H, Rohde H, Golbek T, Roeters S, Woutersen S, Weidner T, Meyer R
ELIFE. 2022;11:.

Reading the Score of the Air-Change in Airborne Microbial Load in Contrast to Particulate Matter during Music Making
Knobling B, Franke G, Beike L, Dickhuth T, Knobloch J
INT J ENV RES PUB HE. 2022;19(16):.

Infectivity of SARS-CoV-2 on Inanimate Surfaces: Don't Trust Ct Value
Knobloch J, Pfefferle S, Lütgehetmann M, Nörz D, Klupp E, Belmar Campos C, Kluge S, Aepfelbacher M, Knobling B, Franke G
INT J ENV RES PUB HE. 2022;19(24):.

An FFP2 respirator mandate for healthcare workers to prevent transmission of SARS-CoV-2 lacks proportionality
Knobloch J, Popp W, Exner M, Walger P, Kampf G
J HOSP INFECT. 2022;130:146-147.

Vertical anti-SARS-CoV-2 monoclonal antibody transfer from mothers to HIV-exposed and unexposed infants
Kobbe R, Schulze-Sturm U, Kurnaz P, Rau C, Tallarek A, Lütgehetmann M, Jordan S, Schmiedel S
AIDS. 2022;36(11):1613-1615.

Assessing and improving the validity of COVID-19 autopsy studies - A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analyses
Krasemann S, Dittmayer C, von Stillfried S, Meinhardt J, Heinrich F, Hartmann K, Pfefferle S, Thies E, von Manitius R, Aschman T, Radke J, Osterloh A, Schmid S, Buhl E, Ihlow J, Dubois F, Arnhold V, Elezkurtaj S, Horst D, Hocke A, Timm S, Bachmann S, Corman V, Goebel H, Matschke J, Stanelle-Bertram S, Gabriel G, Seilhean D, Adle-Biassette H, Ondruschka B, Ochs M, Stenzel W, Heppner F, Boor P, Radbruch H, Laue M, Glatzel M
EBIOMEDICINE. 2022;83:.

The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2
Krasemann S, Haferkamp U, Pfefferle S, Woo M, Heinrich F, Schweizer M, Appelt-Menzel A, Cubukova A, Barenberg J, Leu J, Hartmann K, Thies E, Littau J, Sepulveda-Falla D, Zhang L, Ton K, Liang Y, Matschke J, Ricklefs F, Sauvigny T, Sperhake J, Fitzek A, Gerhartl A, Brachner A, Geiger N, König E, Bodem J, Franzenburg S, Franke A, Moese S, Müller F, Geisslinger G, Claussen C, Kannt A, Zaliani A, Gribbon P, Ondruschka B, Neuhaus W, Friese M, Glatzel M, Pless O
STEM CELL REP. 2022;17(2):307-320.

German Multicenter Study Analyzing Antimicrobial Activity of Ceftazidime-Avibactam of Clinical Meropenem-Resistant Pseudomonas aeruginosa Isolates Using a Commercially Available Broth Microdilution Assay
Manzke J, Stauf R, Neumann B, Molitor E, Hischebeth G, Simon M, Jantsch J, Rödel J, Becker S, Halfmann A, Wichelhaus T, Hogardt M, Serr A, Hess C, Wendel A, Siegel E, Rohde H, Zimmermann S, Steinmann J
ANTIBIOTICS-BASEL. 2022;11(5):.

Young COVID-19 Patients Show a Higher Degree of Microglial Activation When Compared to Controls
Matschke J, Lahann H, Krasemann S, Altmeppen H, Pfefferle S, Galliciotti G, Fitzek A, Sperhake J, Ondruschka B, Busch M, Rotermund N, Schulz K, Lohr C, Dottermusch M, Glatzel M
FRONT NEUROL. 2022;13:.

Efficacy of Tigecycline as Salvage Therapy in Multidrug-Resistant Febrile Neutropenia in Patients with Acute Leukemia-A Single Center Analysis
Modemann F, Härterich S, Schulze Zur Wiesch J, Rohde H, Lindeman N, Bokemeyer C, Fiedler W, Ghandili S
ANTIBIOTICS-BASEL. 2022;11(2):.

Comparing susceptibility and contagiousness in concurrent outbreaks with a non-VOC and the VOC SARS-CoV-2 variant B.1.1.7 in daycare centers in Hamburg, Germany
Nakel J, Robitaille A, Günther T, Rosenau L, Czech-Sioli M, Plenge-Bönig A, Bühler S, Wille A, Jakubowski E, Pruskil S, Wahlen M, Indenbirken D, Nörz D, Lütgehetmann M, Aepfelbacher M, Grundhoff A, Grolle B, Fischer N
INT J HYG ENVIR HEAL. 2022;240:.

Clinical characteristics and comparison of longitudinal qPCR results from different specimen types in a cohort of ambulatory and hospitalized patients infected with monkeypox virus
Nörz D, Brehm T, Tang H, Grewe I, Hermanussen L, Matthews H, Pestel J, Degen O, Günther T, Grundhoff A, Fischer N, Addo M, Jordan S, Hertling S, Unger S, Schäfer G, Schewe K, Hoffmann C, Aepfelbacher M, Pfefferle S, Schulze Zur Wiesch J, Schmiedel S, Lütgehetmann M
J CLIN VIROL. 2022;155:.

Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage Variants
Nörz D, Grunwald M, Tang H, Weinschenk C, Günther T, Robitaille A, Giersch K, Fischer N, Grundhoff A, Aepfelbacher M, Pfefferle S, Lütgehetmann M
VIRUSES-BASEL. 2022;14(3):.

Evidence of surface contamination in hospital rooms occupied by patients infected with monkeypox, Germany, June 2022
Nörz D, Pfefferle S, Brehm T, Franke G, Grewe I, Knobling B, Aepfelbacher M, Huber S, Klupp E, Jordan S, Addo M, Schulze Zur Wiesch J, Schmiedel S, Lütgehetmann M, Knobloch J
EUROSURVEILLANCE. 2022;27(26):.

Rapid Adaptation of Established High-Throughput Molecular Testing Infrastructure for Monkeypox Virus Detection
Nörz D, Tang H, Emmerich P, Giersch K, Fischer N, Schmiedel S, Addo M, Aepfelbacher M, Pfefferle S, Lütgehetmann M
EMERG INFECT DIS. 2022;28(9):1765-1769.

Necrotizing Soft Tissue Infections in Intensive Care
Ogica A, Burdelski C, Rohde H, Kluge S, de Heer G
J INTENSIVE CARE MED. 2022;37(3):393-400.

Anti-SARS-CoV-2 antibodies in breast milk during lactation after infection or vaccination: A cohort study
Olearo F, Radmanesh L, Felber N, von Possel R, Emmerich P, Pekarek N, Pfefferle S, Nörz D, Hansen G, Diemert A, Aepfelbacher M, Hecher K, Lütgehetmann M, Arck P, Tallarek A
J REPROD IMMUNOL. 2022;153:.

Involvement of the Iron-Regulated Loci hts and fhuC in Biofilm Formation and Survival of Staphylococcus epidermidis within the Host
Oliveira F, Lima T, Correia A, Silva A, Soares C, Morais S, Weißelberg S, Vilanova M, Rohde H, Cerca N
MICROBIOL SPECTR. 2022;10(1):.

The Prevalence of Early‐ and Late‐Onset Bacterial, Viral and Fungal Respiratory Superinfections in Invasively Ventilated COVID‐19 Patients.
Paparoupa M, Aldemyati R, Roggenkamp H, Berinson B, Nörz D, Olearo F, Kluge S, Roedl K, Heer G, Wichmann D
J MED VIROL. 2022;94(5):1920-1925.

The effects of SARS-CoV-2 virus type and of vaccination status on causes of death over the course of the COVID-19 pandemic
Paparoupa M, Schröder A, Braunsteiner J, Addo M, Lütgehetmann M, Roedl K, Kluge S, Ondruschka B, Wichmann D
DTSCH ARZTEBL INT. 2022;119(35-36):607-608.

Specific CD4+ T Cell Responses to Ancestral SARS-CoV-2 in Children Increase With Age and Show Cross-Reactivity to Beta Variant
Paul K, Sibbertsen F, Weiskopf D, Lütgehetmann M, Barroso M, Danecka M, Glau L, Hecher L, Hermann K, Kohl A, Oh J, Wiesch J, Sette A, Tolosa E, Vettorazzi E, Woidy M, Zapf A, Zazara D, Mir T, Muntau A, Gersting S, Dunay G
FRONT IMMUNOL. 2022;13:867577.

C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus
Paulowski L, Beckham K, Johansen M, Berneking L, Van N, Degefu Y, Staack S, Sotomayor F, Asar L, Rohde H, Aldridge B, Aepfelbacher M, Parret A, Wilmanns M, Kremer L, Combrink K, Maurer F
PNAS nexus. 2022;1(4):.

Structural basis to repurpose boron-based proteasome inhibitors Bortezomib and Ixazomib as β-lactamase inhibitors
Perbandt M, Werner N, Prester A, Rohde H, Aepfelbacher M, Hinrichs W, Betzel C
SCI REP-UK. 2022;12(1):.

Screening for Monkeypox Infection in Asymptomatic High-Risk-Behaviour Men Having Sex with Men (MSM)
Pestel J, Matthews H, Schmiedel S, Hüfner A, Jordan S, Scheiter R, Lütgehetmann M, Nörz D, Degen O
INFECT DIS REP. 2022;14(5):794-797.

Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme
Petersen E, Goßling A, Adam G, Aepfelbacher M, Behrendt C, Cavus E, Cheng B, Fischer N, Gallinat J, Kühn S, Gerloff C, Koch-Gromus U, Härter M, Hanning U, Huber T, Kluge S, Knobloch J, Kuta P, Schmidt-Lauber C, Lütgehetmann M, Magnussen C, Mayer C, Muellerleile K, Münch J, Nägele F, Petersen M, Renné T, Riedl K, Rimmele D, Schäfer I, Schulz H, Tahir E, Waschki B, Wenzel J, Zeller T, Ziegler A, Thomalla G, Twerenbold R, Blankenberg S
EUR HEART J. 2022;43(11):1124-1137.

Staphylococcus epidermidis-Derived Protease Esp Mediates Proteolytic Activation of Pro‒IL-1β in Human Keratinocytes
Rademacher F, Bartels J, Gläser R, Rodewald M, Schubert S, Drücke D, Rohde H, Harder J
J INVEST DERMATOL. 2022;142(10):2756-2765.e8.

Live imaging of Yersinia translocon formation and immune recognition in host cells
Rudolph M, Carsten A, Kulnik S, Aepfelbacher M, Wolters M
PLOS PATHOG. 2022;18(5):.

SARS-CoV2-specific humoral and T-cell immune response after second vaccination in liver cirrhosis and transplant patients
Ruether D, Schaub G, Duengelhoef P, Haag F, Brehm T, Fathi A, Wehmeyer M, Jahnke-Triankowski J, Mayer L, Hoffmann A, Fischer L, Addo M, Lütgehetmann M, Lohse A, Schulze Zur Wiesch J, Sterneck M
CLIN GASTROENTEROL H. 2022;20(1):162-172.e9.

Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages
Sake S, Kosch C, Blockus S, Haid S, Gunesch A, Zhang X, Friesland M, Trummer S, Grethe C, Kühnel A, Rückert J, Duprex W, Huang J, Rameix-Welti M, Empting M, Fischer N, Hirsch A, Schulz T, Pietschmann T
ANTIMICROB AGENTS CH. 2022;66(12):.

Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice
Schepanski S, Chini M, Sternemann V, Urbschat C, Thiele K, Sun T, Zhao Y, Poburski M, Woestemeier A, Thieme M, Zazara D, Alawi M, Fischer N, Heeren J, Vladimirov N, Woehler A, Puelles V, Bonn S, Gagliani N, Hanganu-Opatz I, Arck P
NAT COMMUN. 2022;13(1):.

Merkel cell carcinoma and immune evasion: Merkel cell polyomavirus small T-antigen induced surface changes can be reverted by therapeutic intervention
Schlemeyer T, Ohnezeit D, Virdi S, Körner C, Weißelberg S, Starzonek S, Schumacher U, Grundhoff A, Indenbirken D, Albertini S, Fischer N
J INVEST DERMATOL. 2022;142(11):3071-3081.e13.

Risk factors for poor humoral response to primary and booster SARS-CoV-2 vaccination in hematologic and oncological outpatients-COVIDOUT study
Schönlein M, Wrage V, Ghandili S, Mellinghoff S, Brehm T, Leypoldt L, Utz N, Schrader R, Alsdorf W, Börschel N, Bußmann L, Schönrock M, Perlick D, Schön G, Verpoort K, Lütgehetmann M, Schulze Zur Wiesch J, Weisel K, Bokemeyer C, Schafhausen P, Sinn M
CANCER CELL. 2022;40(6):581-583.

Comparison of four diagnostic criteria for invasive pulmonary aspergillosis - a diagnostic accuracy study in critically ill patients
Schroeder M, Giese M, Wijaya C, Winterland S, Nuechtern A, Grensemann J, Matthews H, Wichmann D, Stamm J, Rohde H, Christner M, Ozga A, Steurer S, Heinemann A, Simon M, Fischer M, Kluge S
MYCOSES. 2022;65(8):824-833.

Therapeutic Management of COVID-19 in a Pediatric Patient with Neurodegenerative CLN2 Disease and ICV-Enzyme Replacement Therapy: A Case Report
Schwering C, Apostolidou S, Deindl P, Christner M, Knobloch J, Herrmann J, Kobbe R, Schulz A, Singer D, Ebenebe C
NEUROPEDIATRICS. 2022;53(5):381-384.

Impact of Oral Rinsing with Octenidine Based Solution on SARS-CoV-2 Loads in Saliva of Infected Patients an Exploratory Study
Smeets R, Pfefferle S, Büttner H, Knobloch J, Lütgehetmann M
INT J ENV RES PUB HE. 2022;19(9):.

Development of an artificial synovial fluid useful for studying Staphylococcus epidermidis joint infections
Stamm J, Weißelberg S, Both A, Failla A, Nordholt G, Büttner H, Linder S, Aepfelbacher M, Rohde H
FRONT CELL INFECT MI. 2022;12:.

In the Search of Marine Pestiviruses:First Case of Phocoena Pestivirus in a Belt Sea Harbour Porpoise
Stokholm I, Fischer N, Baechlein C, Postel A, Galatius A, Kyhn L, Thøstesen C, Persson S, Siebert U, Olsen M, Becher P
VIRUSES-BASEL. 2022;14(1):.

OP03.03: Factors influencing transplacental transmission of IgG antibodies providing newborns with maternal passive immunity after COVID-19 in pregnancy
Tallarek A, Hollwitz B, Lütgehetmann M, Arck P, Diemert A, Hecher K
ULTRASOUND OBST GYN. 2022;58(S1):65-66.

The Staphylococcus epidermidis Transcriptional Profile During Carriage
Teichmann P, Both A, Wolz C, Hornef M, Rohde H, Yazdi A, Burian M
FRONT MICROBIOL. 2022;13:.

Erratum zu: Milde COVID-19-Verläufe bei Mitarbeitenden einer Universitätsklinik : Die „erste Welle“ am Universitätsklinikum Hamburg-Eppendorf
von Felden J, Brehm T, Schulze Zur Wiesch J, Addo M, Lohse A, Knobloch J, Koch T
BUNDESGESUNDHEITSBLA. 2022;65(3):398.

First report from the German COVID-19 autopsy registry
von Stillfried S, Bülow R, Röhrig R, Boor P
LANCET REG HEALTH-EU. 2022;15:.

Intracranial hemorrhage in COVID-19 patients during extracorporeal membrane oxygenation for acute respiratory failure: a nationwide register study report
von Stillfried S, Bülow R, Röhrig R, Meybohm P, Boor P
CRIT CARE. 2022;26(1):.

Update zur kooperativen autopsiebasierten Forschung in der deutschen Pathologie, Neuropathologie und Gerichtsmedizin
von Stillfried S, Freeborn B, Windeck S, Boor P
PATHOLOGIE. 2022;43(Suppl 1):101-105.

Molecular consequences of SARS-CoV-2 liver tropism
Wanner N, Andrieux G, Badia-I-Mompel P, Edler C, Pfefferle S, Lindenmeyer M, Schmidt-Lauber C, Czogalla J, Wong M, Okabayashi Y, Braun F, Lütgehetmann M, Meister E, Lu S, Noriega M, Günther T, Grundhoff A, Fischer N, Bräuninger H, Lindner D, Westermann D, Haas F, Roedl K, Kluge S, Addo M, Huber S, Lohse A, Reiser J, Ondruschka B, Sperhake J, Saez-Rodriguez J, Boerries M, Hayek S, Aepfelbacher M, Scaturro P, Puelles V, Huber T
NAT METAB. 2022;4(3):310-319.

The circle of life:Phases of podosome formation, turnover and reemergence
Weber K, Hey S, Cervero P, Linder S
EUR J CELL BIOL. 2022;101(2):.

Screening for Schistosoma spp. and Leishmania spp. DNA in Serum of Ghanaian Patients with Acquired Immunodeficiency
Weinreich F, Weinreich F, Hahn A, Hagen R, Rohde H, Sarfo F, Feldt T, Dompreh A, Asibey S, Boateng R, Frickmann H, Eberhardt K
PATHOGENS. 2022;11(7):.

Lack of Evidence of Hepatitis E Virus Infections in a Cohort of Boars and Deer Species in a Game Reserve in Northern Germany
Westphal T, Delling M, Mader M, Ackermann C, Horvatits T, Lütgehetmann M, Schulze zur Wiesch J, Pischke S, Beisel C
Zoonotic Diseases. 2022;2(4):228-233.

New Safety Aspects in Corneal Donation-Studies on SARS-CoV-2-Positive Corneal Donors
Wille D, Heinzelmann J, Kehlen A, Lütgehetmann M, Nörz D, Siebolts U, Mueller A, Karrasch M, Hofmann N, Viestenz A, Börgel M, Kuhn F, Viestenz A
J CLIN MED. 2022;11(12):.

Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive
Zielinski K, Prester A, Andaleeb H, Bui S, Yefanov O, Catapano L, Henkel A, Wiedorn M, Lorbeer O, Crosas E, Meyer J, Mariani V, Domaracky M, White T, Fleckenstein H, Sarrou I, Werner N, Betzel C, Rohde H, Aepfelbacher M, Chapman H, Perbandt M, Steiner R, Oberthuer D
IUCRJ. 2022;9(Pt 6):778-791.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

AUTOPHAGY. 2021.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

AUTOPHAGY. 2021;17(1):1-382.

Fatal COVID-19 in a Child with Persistence of SARS-CoV-2 Despite Extensive Multidisciplinary Treatment: A Case Report
Apostolidou S, Harbauer T, Lasch P, Biermann D, Hempel M, Lütgehetmann M, Pfefferle S, Herrmann J, Rüffer A, Reinshagen K, Kozlik-Feldmann R, Gieras A, Kniep I, Oh J, Singer D, Ebenebe C, Kobbe R
CHILDREN-BASEL. 2021;8(7):.

Practical recommendations for routine cleaning and disinfection procedures in healthcare institutions: a narrative review
Assadian O, Harbarth S, Vos M, Knobloch J, Asensio A, Widmer A
J HOSP INFECT. 2021;113:104-114.

HEV-Associated Neuralgic Amyotrophy : A Multicentric Case Series
Bannasch J, Berger B, Schwartkopp C, Berning M, Goetze O, Panning M, Fritz-Weltin M, Trendelenburg G, Gelderblom M, Lütgehetmann M, Stute F, Horvatits T, Dirks M, Antoni C, Behrendt P, Pischke S
PATHOGENS. 2021;10(6):.

Telmisartan induces a specific gut microbiota signature which may mediate its antiobesity effect
Beckmann L, Künstner A, Freschi M, Huber G, Stölting I, Ibrahim S, Hirose M, Freitag M, Langan E, Matschl U, Galuska C, Fuchs B, Knobloch J, Busch H, Raasch W
PHARMACOL RES. 2021;170:.

Yersinia remodels epigenetic histone modifications in human macrophages
Bekere I, Huang J, Schnapp M, Rudolph M, Berneking L, Ruckdeschel K, Grundhoff A, Günther T, Fischer N, Aepfelbacher M
PLOS PATHOG. 2021;17(11):.

Usefulness of Biofire FilmArray BCID2 for blood culture processing in clinical practice
Berinson B, Both A, Berneking L, Christner M, Lütgehetmann M, Aepfelbacher M, Rohde H
J CLIN MICROBIOL. 2021;59(8):e0054321.

EUCAST rapid antimicrobial susceptibility testing (RAST): analytical performance and impact on patient management
Berinson B, Olearo F, Both A, Brossmann N, Christner M, Aepfelbacher M, Rohde H
J ANTIMICROB CHEMOTH. 2021;76(5):1332-1338.

Performance of a loop-mediated isothermal amplification assay (Isoplex CRE-ART) to detect common carbapenemase-encoding genes in Gram-negative bacteria
Berneking L, Asar L, Both A, Berinson B, Aepfelbacher M, Lütgehetmann M, Rohde H
J MED MICROBIOL. 2021;70(7):.

Performance of the BD Phoenix CPO detect assay for detection and classification of carbapenemase-producing organisms
Berneking L, Both A, Berinson B, Hoffmann A, Lütgehetmann M, Aepfelbacher M, Rohde H
EUR J CLIN MICROBIOL. 2021;40(5):979-985.

Comparison of Two Real-Time PCR Assays Targeting Ribosomal Sequences for the Identification of Cystoisospora belli in Human Stool Samples
Blohm M, Hahn A, Hagen R, Eberhardt K, Rohde H, Leboulle G, Feldt T, Sarfo F, Cristanziano V, Frickmann H, Loderstädt U
PATHOGENS. 2021;10(8):.

Distinct clonal lineages and within-host diversification shape invasive Staphylococcus epidermidis populations
Both A, Huang J, Qi M, Lausmann C, Weißelberg S, Büttner H, Lezius S, Failla A, Christner M, Stegger M, Gehrke T, Baig S, Citak M, Alawi M, Aepfelbacher M, Rohde H
PLOS PATHOG. 2021;17(2):e1009304.

Heatwave-associated Vibrio infections in Germany, 2018 and 2019
Brehm T, Berneking L, Sena Martins M, Dupke S, Jacob D, Drechsel O, Bohnert J, Becker K, Kramer A, Christner M, Aepfelbacher M, Schmiedel S, Rohde H
EUROSURVEILLANCE. 2021;26(41):2002041.

Nicht-Cholera-Vibrionen – derzeit noch seltene, aber wachsende Infektionsgefahr in Nord- und Ostsee
Brehm T, Dupke S, Hauk G, Fickenscher H, Rohde H, Berneking L
INTERNIST. 2021;62(8):876-886.

Patient Characteristics and Clinical Course of COVID-19 Patients Treated at a German Tertiary Center during the First and Second Waves in the Year 2020
Brehm T, Heyer A, Roedl K, Jarczak D, Nierhaus A, Nentwich M, van der Meirschen M, Schultze A, Christner M, Fiedler W, Kröger N, Huber T, Klose H, Sterneck M, Jordan S, Kreuels B, Schmiedel S, Addo M, Huber S, Lohse A, Kluge S, Schulze Zur Wiesch J
J CLIN MED. 2021;10(11):.

Lower Levels of Transaminases but Higher Levels of Serum Creatinine in Patients with Acute Hepatitis E in Comparison to Patients with Hepatitis A
Brehm T, Mazaheri O, Horvatits T, Lütgehetmann M, Schulze Zur Wiesch J, Lohse A, Polywka S, Pischke S
PATHOGENS. 2021;10(1):60.

SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies
Brehm T, Pfefferle S, von Possel R, Kobbe R, Nörz D, Schmiedel S, Grundhoff A, Olearo F, Emmerich P, Robitaille A, Günther T, Braun P, Andersen G, Knobloch J, Addo M, Lohse A, Aepfelbacher M, Fischer N, Schulze Zur Wiesch J, Lütgehetmann M
VIRUSES-BASEL. 2021;13(4):.

Seroprevalence of SARS-CoV-2 antibodies among hospital workers in a German tertiary care center: A sequential follow-up study
Brehm T, Schwinge D, Lampalzer S, Schlicker V, Küchen J, Thompson M, Ullrich F, Huber S, Schmiedel S, Addo M, Lütgehetmann M, Knobloch J, Schulze Zur Wiesch J, Lohse A
INT J HYG ENVIR HEAL. 2021;232:.

Low SARS-CoV-2 infection rates and high vaccine-induced immunity among German healthcare workers at the end of the third wave of the COVID-19 pandemic
Brehm T, Thompson M, Ullrich F, Schwinge D, Addo M, Spier A, Knobloch J, Aepfelbacher M, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
INT J HYG ENVIR HEAL. 2021;238:.

Comparison of clinical characteristics and disease outcome of COVID-19 and seasonal influenza
Brehm T, van der Meirschen M, Hennigs A, Roedl K, Jarczak D, Wichmann D, Frings D, Nierhaus A, Oqueka T, Fiedler W, Christopeit M, Kraef C, Schultze A, Lütgehetmann M, Addo M, Schmiedel S, Kluge S, Schulze Zur Wiesch J
SCI REP-UK. 2021;11(1):.

Presence of SARS-CoV-2 RNA in the Cornea of Viremic Patients With COVID-19
Casagrande M, Fitzek A, Spitzer M, Püschel K, Glatzel M, Krasemann S, Nörz D, Lütgehetmann M, Pfefferle S, Schultheiss M
JAMA OPHTHALMOL. 2021;139(4):383-388.

Nectin stabilization at adherens junctions is counteracted by Rab5a-dependent endocytosis
Cervero P, Vrenken K, Klose M, Rehm K, Linder S
EUR J CELL BIOL. 2021;100(7-8):.

Contamination of multi dose eyedrops in the intra and perioperative context
Daehn T, Schneider A, Knobloch J, Hellwinkel O, Spitzer M, Kromer R
SCI REP-UK. 2021;11(1):.

Innate immunity in hepatitis B and D virus infection: consequences for viral persistence, inflammation, and T cell recognition
Dandri M, Bertoletti A, Lütgehetmann M
SEMIN IMMUNOPATHOL. 2021;43(4):535-548.

Recommendations for the introduction of metagenomic next-generation sequencing in clinical virology, part II:bioinformatic analysis and reporting
de Vries J, Brown J, Couto N, Beer M, Le Mercier P, Sidorov I, Papa A, Fischer N, Oude Munnink B, Rodriquez C, Zaheri M, Sayiner A, Hönemann M, Cataluna A, Carbo E, Bachofen C, Kubacki J, Schmitz D, Tsioka K, Matamoros S, Höper D, Hernandez M, Puchhammer-Stöckl E, Lebrand A, Huber M, Simmonds P, Claas E, López-Labrador F
J CLIN VIROL. 2021;138:.

Benchmark of thirteen bioinformatic pipelines for metagenomic virus diagnostics using datasets from clinical samples
de Vries J, Brown J, Fischer N, Sidorov I, Morfopoulou S, Huang J, Munnink B, Sayiner A, Bulgurcu A, Rodriguez C, Gricourt G, Keyaerts E, Beller L, Bachofen C, Kubacki J, Samuel C, Florian L, Dennis S, Beer M, Hoeper D, Huber M, Kufner V, Zaheri M, Lebrand A, Papa A, van Boheemen S, Kroes A, Breuer J, Lopez-Labrador F, Claas E
J CLIN VIROL. 2021;141:.

Staphylococcus epidermidis clones express Staphylococcus aureus-type wall teichoic acid to shift from a commensal to pathogen lifestyle
Du X, Larsen J, Li M, Walter A, Slavetinsky C, Both A, Sanchez Carballo P, Stegger M, Lehmann E, Liu Y, Liu J, Slavetinsky J, Duda K, Krismer B, Heilbronner S, Weidenmaier C, Mayer C, Rohde H, Winstel V, Peschel A
NAT MICROBIOL. 2021;6(6):757-768.

Intestinal Colonization with Tropheryma whipplei—Clinical and Immunological Implications for HIV Positive Adults in Ghana
Eberhardt K, Sarfo F, Klupp E, Dompreh A, Cristanziano V, Kuffour E, Boateng R, Norman B, Phillips R, Aepfelbacher M, Feldt T
MICROORGANISMS. 2021;9(8):1781.

Real time, in-line optical mapping of single molecules of DNA
Esmek F, Erichlandwehr T, Mors D, Czech-Sioli M, Therre M, Günther T, Grundhoff A, Fischer N, Fernandez-Cuesta I
Biosensors and Bioelectronics: X. 2021;9:.

Retrospective analysis of bacterial colonization of necrotic bone and antibiotic resistance in 98 patients with medication-related osteonecrosis of the jaw (MRONJ)
Ewald F, Wuesthoff F, Koehnke R, Friedrich R, Gosau M, Smeets R, Rohde H, Assaf A
CLIN ORAL INVEST. 2021;25(5):2801-2809.

Prospective postmortem evaluation of 735 consecutive SARS-CoV-2-associated death cases
Fitzek A, Schädler J, Dietz E, Ron A, Gerling M, Kammal A, Lohner L, Falck C, Möbius D, Goebels H, Gerberding A, Schröder A, Sperhake J, Klein A, Fröb D, Mushumba H, Wilmes S, Anders S, Kniep I, Heinrich F, Langenwalder F, Meißner K, Lange P, Zapf A, Püschel K, Heinemann A, Glatzel M, Matschke J, Aepfelbacher M, Lütgehetmann M, Steurer S, Thorns C, Edler C, Ondruschka B
SCI REP-UK. 2021;11(1):19342.

An automated room disinfection system using ozone is highly active against surrogates for SARS-CoV-2
Franke G, Knobling B, Brill F, Becker B, Klupp E, Belmar Campos C, Pfefferle S, Lütgehetmann M, Knobloch J
J HOSP INFECT. 2021;112:108-113.

Clinical evaluation of a laboratory-developed quantitative BK virus-PCR assay using the cobas® omni Utility Channel
Fritzsche A, Berneking L, Nörz D, Reucher S, Fischer N, Roggenkamp H, Aepfelbacher M, Rohde H, Pfefferle S, Lütgehetmann M
J VIROL METHODS. 2021;290:114093.

Low incidence of COVID-19 in a prospective cohort of patients with liver cirrhosis and hepatocellular carcinoma treated at a tertiary medical center during the 2020 pandemic
Fründt T, Kuballa L, Lütgehetman M, Nörz D, Arend H, Brehm T, Schulze Zur Wiesch J, Horvatits T, Horvatits K, Huber S, Wege H, Kluwe J
PLOS ONE. 2021;16(12):e0258450.

Post-Vaccination Anti-SARS-CoV-2-Antibody Response in Patients with Multiple Myeloma Correlates with Low CD19+ B-Lymphocyte Count and Anti-CD38 Treatment
Ghandili S, Schönlein M, Lütgehetmann M, Wiesch J, Becher H, Bokemeyer C, Sinn M, Weisel K, Leypoldt L
CANCERS. 2021;13(15):.

Lymphocytopenia and Anti-CD38 Directed Treatment Impact the Serological SARS-CoV-2 Response after Prime Boost Vaccination in Patients with Multiple Myeloma
Ghandili S, Schönlein M, Wiessner C, Becher H, Lütgehetmann M, Brehm T, Wiesch J, Bokemeyer C, Sinn M, Weisel K, Leypoldt L
J CLIN MED. 2021;10(23):.

Murine hepatocytes do not support persistence of Hepatitis D Virus mono-infection in vivo
Giersch K, Hermanussen L, Volz T, Kah J, Allweiss L, Casey J, Sureau C, Dandri M, Lütgehetmann M
LIVER INT. 2021;41(2):410-419.

Strong Replication Interference Between Hepatitis Delta Viruses in Human Liver Chimeric Mice
Giersch K, Hermanussen L, Volz T, Volmari A, Allweiss L, Sureau C, Casey J, Huang J, Fischer N, Lütgehetmann M, Dandri M
FRONT MICROBIOL. 2021;12:671466.

Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolved COVID-19
Heide J, Schulte S, Kohsar M, Brehm T, Herrmann M, Karsten H, Marget M, Peine S, Johansson A, Sette A, Lütgehetmann M, Kwok W, Sidney J, Schulze Zur Wiesch J
PLOS PATHOG. 2021;17(9):.

Polymicrobial enteric infections in african infants with diarrhoea - Results from a longitudinal prospective case-control study
Heinemann M, Strauchs C, Lütgehetmann M, Aepfelbacher M, Klupp E, Owusu-Dabo E, Rolling T, Cramer J, Vinnemeier C
CLIN MICROBIOL INFEC. 2021;27(12):1792-1798.

Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa
Heinrich F, Meißner K, Langenwalder F, Püschel K, Hoffmann A, Lütgehetmann M, Aepfelbacher M, Bibiza-Freiwald E, Pfefferle S, Heinemann A
EMERG INFECT DIS. 2021;27(1):329-331.

SARS-CoV-2 Blood RNA Load Predicts Outcome in Critically Ill COVID-19 Patients
Heinrich F, Nentwich M, Bibiza-Freiwald E, Nörz D, Roedl K, Christner M, Hoffmann A, Olearo F, Kluge S, Aepfelbacher M, Wichmann D, Lütgehetmann M, Pfefferle S
OPEN FORUM INFECT DI. 2021;8(11):.

Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model
Heyckendorf J, Marwitz S, Reimann M, Avsar K, DiNardo A, Günther G, Hoelscher M, Ibraim E, Kalsdorf B, Kaufmann S, Kontsevaya I, van Leth F, Mandalakas A, Maurer F, Müller M, Nitschkowski D, Olaru I, Popa C, Rachow A, Rolling T, Rybniker J, Salzer H, Sanchez-Carballo P, Schuhmann M, Schaub D, Spinu V, Suárez I, Terhalle E, Unnewehr M, Weiner J, Goldmann T, Lange C
EUR RESPIR J. 2021;58(3):2003492.

Molecular Epidemiology of Carbapenem-Resistant Acinetobacter baumannii Strains Isolated at the German Military Field Laboratory in Mazar-e Sharif, Afghanistan
Higgins P, Kniel M, Rojak S, Balczun C, Rohde H, Frickmann H, Hagen R
MICROORGANISMS. 2021;9(11):.

Hepatitis E virus persists in the ejaculate of chronically infected men
Horvatits T, Wißmann J, Johne R, Groschup M, Gadicherla A, Wiesch J, Eiden M, Todt D, Reimer R, Dähnert L, Schöbel A, Horvatits K, Lübke R, Wolschke C, Ayuk F, Rybczynski M, Lohse A, Addo M, Herker E, Lütgehetmann M, Steinmann E, Pischke S
J HEPATOL. 2021;75(1):55-63.

Simulation of Folding Kinetics for Aligned RNAs
Huang J, Voß B
GENES-BASEL. 2021;12(3):.

KIR3DS1 directs NK cell-mediated protection against human adenovirus infections
Jung J, Ching W, Baumdick M, Hofmann-Sieber H, Bosse J, Koyro T, Möller K, Wegner L, Niehrs A, Russu K, Ohms M, Zhang W, Ehrhardt A, Duisters K, Spierings E, Hölzemer A, Körner C, Jansen S, Peine S, Königs I, Lütgehetmann M, Perez D, Reinshagen K, Lindemans C, Altfeld M, Belderbos M, Dobner T, Bunders M
SCI IMMUNOL. 2021;6(63):.

Complete genome sequencing and molecular characterization of SARS-COV-2 from COVID-19 cases in Alborz province in Iran
Kaffashi A, Huang J, Bairami A, Fallah Mehrabadi M, Yaslianifard S, Bashashati M, Banihashemi S, Soleimanifar F, Lotfi M, Taghizadeh M, Soleimani A, Khorasani A, Moshiri F, Mozhgani S
HELIYON. 2021;7(9):.

SARS-CoV-2-Zufallsentdeckungen bei Hamburger Todesfällen: ein epidemiologisches Monitoring während des dynamischen Infektionsgeschehens im Frühjahr 2020
Klein A, Langenwalder F, Heinrich F, Meißner K, Schröder A, Püschel K, Ondruschka B, Lütgehetmann M, Heinemann A
RECHTSMEDIZIN. 2021;31:427-433.

FIB/SEM-based analysis of Borrelia intracellular processing by human macrophages
Klose M, Scheungrab M, Luckner M, Wanner G, Linder S
J CELL SCI. 2021;134(5):.

Aspergillosis: emerging risk groups in critically ill patients
Kluge S, Strauß R, Kochanek M, Weigand M, Rohde H, Lahmer T
MED MYCOL. 2021;60(1):.

Evaluation of the Effectiveness of Two Automated Room Decontamination Devices Under Real-Life Conditions
Knobling B, Franke G, Klupp E, Belmar Campos C, Knobloch J
FRONT PUBLIC HEALTH. 2021;9:.

A resampling strategy for studying robustness in virus detection pipelines
Kohls M, Saremi B, Muchsin I, Fischer N, Becher P, Jung K
COMPUT BIOL CHEM. 2021;94:.

Cefiderocol in Critically Ill Patients with Multi-Drug Resistant Pathogens: Real-Life Data on Pharmacokinetics and Microbiological Surveillance
König C, Both A, Rohde H, Kluge S, Frey O, Röhr A, Wichmann D
ANTIBIOTICS-BASEL. 2021;10(6):649.

Correction: König et al. Cefiderocol in Critically Ill Patients with Multi-Drug Resistant Pathogens: Real-Life Data on Pharmacokinetics and Microbiological Surveillance. Antibiotics 2021, 10, 649
König C, Both A, Rohde H, Kluge S, Frey O, Röhr A, Wichmann D
ANTIBIOTICS-BASEL. 2021;10(10):.

Upregulation of HLA-F expression by BK polyomavirus infection induces immune recognition by KIR3DS1-positive natural killer cells
Koyro T, Kraus E, Lunemann S, Hölzemer A, Wulf S, Jung J, Fittje P, Henseling F, Körner C, Huber T, Grundhoff A, Wiech T, Panzer U, Fischer N, Altfeld M
KIDNEY INT. 2021;99(5):1140-1148.

Bacterial adhesion characteristics on implant materials for intervertebral cages: titanium or PEEK for spinal infections?
Krätzig T, Mende K, Mohme M, von Kroge S, Stangenberg M, Dreimann M, Westphal M, Weisselberg S, Eicker S
EUR SPINE J. 2021;30(6):1774-1782.

Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I:Wet lab procedure
López-Labrador F, Brown J, Fischer N, Harvala H, Van Boheemen S, Cinek O, Sayiner A, Madsen T, Auvinen E, Kufner V, Huber M, Rodriguez C, Jonges M, Hönemann M, Susi P, Sousa H, Klapper P, Pérez-Cataluňa A, Hernandez M, Molenkamp R, der Hoek L, Schuurman R, Couto N, Leuzinger K, Simmonds P, Beer M, Höper D, Kamminga S, Feltkamp M, Rodríguez-Díaz J, Keyaerts E, Nielsen X, Puchhammer-Stöckl E, Kroes A, Buesa J, Breuer J, Claas E, de Vries J
J CLIN VIROL. 2021;134:.

Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis
Moreno-Layseca P, Jäntti N, Godbole R, Sommer C, Jacquemet G, Al-Akhrass H, Conway J, Kronqvist P, Kallionpää R, Oliveira-Ferrer L, Cervero P, Linder S, Aepfelbacher M, Zauber H, Rae J, Parton R, Disanza A, Scita G, Mayor S, Selbach M, Veltel S, Ivaska J
NAT CELL BIOL. 2021;23(10):1073-1084.

Evaluation of a fully automated high-throughput SARS-CoV-2 multiplex qPCR assay with built-in screening functionality for del-HV69/70- and N501Y variants such as B.1.1.7
Nörz D, Grunwald M, Olearo F, Fischer N, Aepfelbacher M, Pfefferle S, Lütgehetmann M
J CLIN VIROL. 2021;141:.

Rapid Automated Screening for SARS-CoV-2 B.1.617 Lineage Variants (Delta/Kappa) through a Versatile Toolset of qPCR-Based SNP Detection
Nörz D, Grunwald M, Tang H, Olearo F, Günther T, Robitaille A, Fischer N, Grundhoff A, Aepfelbacher M, Pfefferle S, Lütgehetmann M
DIAGNOSTICS. 2021;11(10):.

Clinical evaluation of a fully automated, laboratory-developed multiplex RT-PCR assay integrating dual-target SARS-CoV-2 and influenza A/B detection on a high-throughput platform
Nörz D, Hoffmann A, Aepfelbacher M, Pfefferle S, Lütgehetmann M
J MED MICROBIOL. 2021;70(2):.

Multicenter Evaluation of a Fully Automated High-Throughput SARS-CoV-2 Antigen Immunoassay
Nörz D, Olearo F, Perisic S, Bauer M, Riester E, Schneider T, Schönfeld K, Laengin T, Lütgehetmann M
INFECT DIS THER. 2021;10(4):2371-2379.

Modifying a Diagnostic SARS-CoV-2 Spike PCR to Turn a Del69/70 Dropout into a Discriminatory On-Target Assay
Nörz D, Pfefferle S, Grunwald M, Fischer N, Aepfelbacher M, Lütgehetmann M
J MOL DIAGN. 2021;23(6):777-778.

Implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis
Ntalos D, Schoof B, Thiesen D, Viezens L, Kleinertz H, Rohde H, Both A, Luebke A, Strahl A, Dreimann M, Stangenberg M
SCI REP-UK. 2021;11(1):9515.

Emergence of linezolid-resistance in vancomycin-resistant Enterococcus faecium ST117 associated with increased linezolid-consumption
Olearo F, Both A, Belmar Campos C, Hilgarth H, Klupp E, Hansen J, Maurer F, Christner M, Aepfelbacher M, Rohde H
INT J MED MICROBIOL. 2021;311(2):.

Handling and accuracy of four rapid antigen tests for the diagnosis of SARS-CoV-2 compared to RT-qPCR
Olearo F, Nörz D, Heinrich F, Sutter J, Roedl K, Schultze A, Wiesch J, Braun P, Oestereich L, Kreuels B, Wichmann D, Aepfelbacher M, Pfefferle S, Lütgehetmann M
J CLIN VIROL. 2021;137:.

Clinical performance and accuracy of a qPCR-based SARS-CoV-2 mass-screening workflow for healthcare-worker surveillance using pooled self-sampled gargling solutions: a cross-sectional study
Olearo F, Nörz D, Hoffman A, Grunwald M, Gatzemeyer K, Christner M, Both A, Campos C, Braun P, Andersen G, Pfefferle S, Zapf A, Aepfelbacher M, Knobloch J, Lütgehetmann M
J INFECTION. 2021;83(5):589-593.

Siderophore-Mediated Iron Acquisition Plays a Critical Role in Biofilm Formation and Survival of Staphylococcus epidermidis Within the Host
Oliveira F, Lima T, Correia A, Silva A, Soares C, Morais S, Weißelberg S, Vilanova M, Rohde H, Cerca N
FRONT MED-LAUSANNE. 2021;8:.

Fighting Staphylococcus epidermidis Biofilm-Associated Infections: Can Iron Be the Key to Success?
Oliveira F, Rohde H, Vilanova M, Cerca N
FRONT CELL INFECT MI. 2021;11:.

The Emerging Role of Iron Acquisition in Biofilm-Associated Infections
Oliveira F, Rohde H, Vilanova M, Cerca N
TRENDS MICROBIOL. 2021;29(9):772-775.

Multiorgan tropism of SARS-CoV-2 lineage B.1.1.7
Ondruschka B, Heinrich F, Lindenmeyer M, Edler C, Möbius D, Czogalla J, Heinemann A, Braun F, Aepfelbacher M, Lütgehetmann M, Huber T
INT J LEGAL MED. 2021;135(6):2347-2349.

An inter‑laboratory study to investigate the impact of the bioinformatics component on microbiome analysis using mock communities
O’Sullivan D, Doyle R, Temisak S, Redshaw N, Whale A, Logan G, Huang J, Fischer N, Amos G, Preston M, Marchesi J, Wagner J, Parkhill J, Motro Y, Denise H, Finn R, Kay G, O'Grady J, Ransom-Jones E, Wu H, Laing E, Benavente E, Phelan J, Clark T, Moran-Gilad J, Huggett J
SCI REP-UK. 2021;11(1):10590.

Bacteriophage Rescue Therapy of a Vancomycin-Resistant Enterococcus faecium Infection in a One-Year-Old Child following a Third Liver Transplantation
Paul K, Merabishvili M, Hazan R, Christner M, Herden U, Gelman D, Khalifa L, Yerushalmy O, Coppenhagen-Glazer S, Harbauer T, Schulz-Jürgensen S, Rohde H, Fischer L, Aslam S, Rohde C, Nir-Paz R, Pirnay J, Singer D, Muntau A
VIRUSES-BASEL. 2021;13(9):1785.

SARS Coronavirus-2 variant tracing within the first Coronavirus Disease 19 clusters in northern Germany
Pfefferle S, Günther T, Kobbe R, Czech-Sioli M, Nörz D, Santer R, Oh J, Kluge S, Oestereich L, Peldschus K, Indenbirken D, Huang J, Grundhoff A, Aepfelbacher M, Knobloch J, Lütgehetmann M, Fischer N
CLIN MICROBIOL INFEC. 2021;27(1):130.e5-130.e8.

Clinical establishment of a laboratory developed quantitative HDV PCR assay on the cobas6800 high-throughput system
Pflüger L, Nörz D, Volz T, Giersch K, Giese A, Goldmann N, Glebe D, Bockmann J, Pfefferle S, Dandri M, Schulze Zur Wiesch J, Lütgehetmann M
JHEP REP. 2021;3(6):.

Hepatitis delta virus propagation enabled by hepatitis C virus - scientifically intriguing; but is it relevant to clinical practice?
Pflüger L, Schulze Zur Wiesch J, Polywka S, Lütgehetmann M
J VIRAL HEPATITIS. 2021;28(1):213-216.

Viral Dynamics of SARS-CoV-2 in Critically Ill Allogeneic Hematopoietic Stem Cell Transplant Recipients and Immunocompetent Patients with COVID-19
Roedl K, Heidenreich S, Pfefferle S, Jarczak D, Urbanowicz T, Nörz D, Aepfelbacher M, Kröger N, Kluge S, Lütgehetmann M, Christopeit M, Wichmann D
AM J RESP CRIT CARE. 2021;203(2):242-245.

Severe liver dysfunction complicating course of COVID-19 in the critically ill: multifactorial cause or direct viral effect?
Roedl K, Jarczak D, Drolz A, Wichmann D, Boenisch O, de Heer G, Burdelski C, Frings D, Sensen B, Nierhaus A, Lütgehetmann M, Kluge S, Fuhrmann V
ANN INTENSIVE CARE. 2021;11(1):.

The handling of SARS-CoV-2 associated deaths - infectivity of the body
Schröder A, Edler C, Ondruschka B, Püschel K, Schädler J, Heinemann A, Heinrich F, Lütgehetmann M, Pfefferle S, Aepfelbacher M, Fitzek A, Sperhake J
FORENSIC SCI MED PAT. 2021;17(3):411-418.

Development of the "Hamburg Best Practice Guidelines for ICV-Enzyme Replacement therapy (ERT) in CLN2 Disease" Based on 6 Years Treatment Experience in 48 Patients
Schwering C, Kammler G, Wibbeler E, Christner M, Knobloch J, Nickel M, Denecke J, Baehr M, Schulz A
J CHILD NEUROL. 2021;36(8):635-641.

Host factors abolish the need for polysaccharides and extracellular matrix-binding protein in Staphylococcus epidermidis biofilm formation
Skovdal S, Hansen L, Ivarsen D, Zeng G, Büttner H, Rohde H, Jørgensen N, Meyer R
J MED MICROBIOL. 2021;70(3):.

Influence of microbiological diagnosis on the clinical course of spondylodiscitis
Stangenberg M, Mende K, Mohme M, Krätzig T, Viezens L, Both A, Rohde H, Dreimann M
INFECTION. 2021;49(5):1017-1027.

Vertically transferred maternal immune cells promote neonatal immunity against early life infections
Stelzer I, Urbschat C, Schepanski S, Thiele K, Triviai I, Wieczorek A, Alawi M, Ohnezeit D, Kottlau J, Huang J, Fischer N, Mittrücker H, Solano M, Fehse B, Diemert A, Stahl F, Arck P
NAT COMMUN. 2021;12(1):4706.

Inefficient Placental Virus Replication and Absence of Neonatal Cell-Specific Immunity Upon Sars-CoV-2 Infection During Pregnancy
Tallarek A, Urbschat C, Fonseca Brito L, Stanelle-Bertram S, Krasemann S, Frascaroli G, Thiele K, Wieczorek A, Felber N, Lütgehetmann M, Markert U, Hecher K, Brune W, Stahl F, Gabriel G, Diemert A, Arck P
FRONT IMMUNOL. 2021;12:698578.

Less than you'd think-a prospective study on MRSA-colonization in healthy travellers
Tran D, Winter D, Christner M, Ramharter M, Addo M, Rolling T, Vinnemeier C, Koch T
J TRAVEL MED. 2021;28(3):.

Milde COVID-19-Verläufe bei Mitarbeitenden einer Universitätsklinik: Die „erste Welle“ am Universitätsklinikum Hamburg-Eppendorf
von Felden J, Brehm T, Schulze-Zur-Wiesch J, Addo M, Lohse A, Knobloch J, Koch T
BUNDESGESUNDHEITSBLA. 2021;64(9):1165-1168.

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
Wenzel J, Lampe J, Müller-Fielitz H, Schuster R, Zille M, Müller K, Krohn M, Körbelin J, Zhang L, Özorhan Ü, Neve V, Wagner J, Bojkova D, Shumliakivska M, Jiang Y, Fähnrich A, Ott F, Sencio V, Robil C, Pfefferle S, Sauve F, Coêlho C, Franz J, Spiecker F, Lembrich B, Binder S, Feller N, König P, Busch H, Collin L, Villaseñor R, Jöhren O, Altmeppen H, Pasparakis M, Dimmeler S, Cinatl J, Püschel K, Zelic M, Ofengeim D, Stadelmann C, Trottein F, Nogueiras R, Hilgenfeld R, Glatzel M, Prevot V, Schwaninger M
NAT NEUROSCI. 2021;24(11):1522-1533.

B cell analysis in SARS‐CoV‐2 versus malaria: Increased frequencies of plasmablasts and atypical memory B cells in COVID‐19
Wildner N, Ahmadi P, Schulte S, Brauneck F, Kohsar M, Lütgehetmann M, Beisel C, Addo M, Haag F, Schulze zur Wiesch J
J LEUKOCYTE BIOL. 2021;109(1):77-90.

Molecular Mechanisms of Borrelia burgdorferi Phagocytosis and Intracellular Processing by Human Macrophages
Woitzik P, Linder S
BIOLOGY-BASEL. 2021;10(7):567.

Control of SARS-CoV-2 infection in rituximab-treated neuroimmunological patients
Woo M, Steins D, Häußler V, Kohsar M, Haag F, Elias-Hamp B, Heesen C, Lütgehetmann M, Schulze Zur Wiesch J, Friese M
J NEUROL. 2021;268(1):5-7.

Rätselhafte B-Symptomatik bei einem 61-Jährigen unter Therapie einer rheumatoiden Arthritis
Wüstenberg R, Christner M, Schmiedel S, Tariparast A, Wichmann D, Lennartz M, Klose H, Kluge S
INTERNIST. 2021;62(11):1231-1236.

Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients
Zhao Y, Kilian C, Turner J, Bosurgi L, Roedl K, Bartsch P, Gnirck A, Cortesi F, Schultheiß C, Hellmig M, Enk L, Hausmann F, Borchers A, Wong M, Paust H, Siracusa F, Scheibel N, Herrmann M, Rosati E, Bacher P, Kylies D, Jarczak D, Lütgehetmann M, Pfefferle S, Steurer S, Zur Wiesch J, Puelles V, Sperhake J, Addo M, Lohse A, Binder M, Huber S, Huber T, Kluge S, Bonn S, Panzer U, Gagliani N, Krebs C
SCI IMMUNOL. 2021;6(56):.

Merkel Cell Polyomavirus Encodes Circular RNAs (circRNAs) Enabling a Dynamic circRNA/microRNA/mRNA Regulatory Network
Abere B, Zhou H, Li J, Cao S, Toptan T, Grundhoff A, Fischer N, Moore P, Chang Y
MBIO. 2020;11(6):.

Emergence of coagulase-negative staphylococci
Becker K, Both A, Weißelberg S, Heilmann C, Rohde H
EXPERT REV ANTI-INFE. 2020;18(4):349-366.

Identification of Kosakonia cowanii as a rare cause of acute cholecystitis:case report and review of the literature
Berinson B, Bellon E, Christner M, Both A, Aepfelbacher M, Rohde H
BMC INFECT DIS. 2020;20(1):366.

High rates of cirrhosis and severe clinical events in patients with HBV/HDV co-infection:longitudinal analysis of a German cohort:longitudinal analysis of a German cohort
Bockmann J, Grube M, Hamed V, von Felden J, Landahl J, Wehmeyer M, Giersch K, Hall M, Murray J, Dandri M, Lüth S, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
BMC GASTROENTEROL. 2020;20(1):24.

Rapid identification of the vanA/vanB resistance determinant in Enterococcus sp. from blood cultures using the Cepheid Xpert vanA/vanB cartridge system
Both A, Berneking L, Berinson B, Lütgehetmann M, Christner M, Aepfelbacher M, Rohde H
DIAGN MICR INFEC DIS. 2020;96(4):114977.

SARS-CoV-2 renal tropism associates with acute kidney injury
Braun F, Lütgehetmann M, Pfefferle S, Wong M, Carsten A, Lindenmeyer M, Nörz D, Heinrich F, Meißner K, Wichmann D, Kluge S, Gross O, Pueschel K, Schröder A, Edler C, Aepfelbacher M, Puelles V, Huber T
LANCET. 2020;396(10251):597-598.

Wound infection with Vibrio harveyi following a traumatic leg amputation after a motorboat propeller injury in Mallorca, Spain:a case report and review of literature
Brehm T, Berneking L, Rohde H, Chistner M, Schlickewei C, Sena Martins M, Schmiedel S
BMC INFECT DIS. 2020;20(1):104.

Risk factors for different intestinal pathogens among patients with traveler's diarrhea: A retrospective analysis at a German travel clinic (2009-2017)
Brehm T, Lütgehetmann M, Tannich E, Addo M, Lohse A, Rolling T, Vinnemeier C
TRAVEL MED INFECT DI. 2020;37:101706.

High effectiveness of multimodal infection control interventions in preventing SARS−CoV−2 infections in healthcare professionals: a prospective longitudinal seroconversion study
Brehm T, Schwinge D, Lampalzer S, Schlicker V, Küchen J, Thompson M, Ullrich F, Huber S, Schmiedel S, Addo M, Lütgehetmann M, Knobloch J, Schulze zur Wiesch J, Lohse A
medRxiv BMJ. 2020.

A Giant Extracellular Matrix Binding Protein of Staphylococcus epidermidis Binds Surface-Immobilized Fibronectin via a Novel Mechanism
Büttner H, Perbandt M, Kohler T, Kikhney A, Wolters M, Christner M, Heise M, Wilde J, Weißelberg S, Both A, Betzel C, Hammerschmidt S, Svergun D, Aepfelbacher M, Rohde H
MBIO. 2020;11(5):.

Detection of SARS-CoV-2 in Human Retinal Biopsies of Deceased COVID-19 Patients
Casagrande M, Fitzek A, Püschel K, Aleshcheva G, Schultheiss H, Berneking L, Spitzer M, Schultheiss M
OCUL IMMUNOL INFLAMM. 2020;28(5):721-725.

High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms
Czech-Sioli M, Günther T, Therre M, Spohn M, Indenbirken D, Theiss J, Riethdorf S, Qi M, Alawi M, Wülbeck C, Fernandez-Cuesta I, Esmek F, Becker J, Grundhoff A, Fischer N
PLOS PATHOG. 2020;16(8):.

The Ubiquitin specific Protease Usp7, a novel Merkel cell polyomavirus Large T-Antigen interaction partner, modulates viral DNA replication
Czech-Sioli M, Siebels S, Radau S, Zahedi R, Schmidt C, Dobner T, Grundhoff A, Fischer N
J VIROL. 2020;94(5):.

Correction to:Dying with SARS-CoV-2 infection-an autopsy study of the first consecutive 80 cases in Hamburg, Germany
Edler C, Schröder A, Aepfelbacher M, Fitzek A, Heinemann A, Heinrich F, Klein A, Langenwalder F, Lütgehetmann M, Meißner K, Püschel K, Schädler J, Steurer S, Mushumba H, Sperhake J
INT J LEGAL MED. 2020;134(5):1977.

Dying with SARS-CoV-2 infection-an autopsy study of the first consecutive 80 cases in Hamburg, Germany
Edler C, Schröder A, Aepfelbacher M, Fitzek A, Heinemann A, Heinrich F, Klein A, Langenwalder F, Lütgehetmann M, Meißner K, Püschel K, Schädler J, Steurer S, Mushumba H, Sperhake J
INT J LEGAL MED. 2020;134(4):1275-1284.

Detection of C. difficile toxin as a model assay for performing fully automated high-throughput RT-PCR on clinical stool samples
Eigner U, Nörz D, Reucher S, Furrer J, Sun J, Chu K, Kolb M, Hefner N, Pfefferle S, Lütgehetmann M
J MICROBIOL METH. 2020;172:105882.

Infection-induced epigenetic changes and their impact on the pathogenesis of diseases
Fischer N
SEMIN IMMUNOPATHOL. 2020;42(2):127-130.

Evidence for systematic autopsies in COVID-19 positive deceased:Case report of the first German investigated COVID-19 death
Fitzek A, Sperhake J, Edler C, Schröder A, Heinemann A, Heinrich F, Ron A, Mushumba H, Lütgehetmann M, Püschel K
RECHTSMEDIZIN. 2020;1-6.

Autoantibodies to intracellular "rods and rings" structures in two patients with autoimmune hepatitis treated with azathioprine
Galaski J, Koop A, Lütgehetmann M, Lohse A, Weiler-Normann C
AUTOIMMUNITY. 2020;53(6):362-365.

Challenges in treatment of patients with acute leukemia and COVID-19: a series of 12 patients
Ghandili S, Pfefferle S, Roedl K, Sonnemann P, Karagiannis P, Boenisch O, Kluge S, Schmiedel S, Ittrich H, Rohde H, Lütgehetmann M, Weisel K, Bokemeyer C, Wichmann D, Fiedler W, Jarczak D, Modemann F
BLOOD ADV. 2020;4(23):5936-5941.

Antibiotic sensitivity in correlation to the origin of secondary peritonitis: a single center analysis
Grotelüschen R, Heidelmann L, Lütgehetmann M, Melling N, Reeh M, Ghadban T, Dupree A, Izbicki J, Bachmann K
SCI REP-UK. 2020;10(1):18588.

SARS-CoV-2 outbreak investigation in a German meat processing plant
Günther T, Czech-Sioli M, Indenbirken D, Robitaille A, Tenhaken P, Exner M, Ottinger M, Fischer N, Grundhoff A, Brinkmann M
EMBO MOL MED. 2020;12(12):e13296.

Temporal Changes in Patient-Matched Staphylococcus epidermidis Isolates from Infections:towards Defining a 'True' Persistent Infection
Harris L, Bodger O, Post V, Mack D, Morgenstern M, Rohde H, Moriarty T, Wilkinson T
MICROORGANISMS. 2020;8(10):.

Germany's first COVID-19 deceased:a 59-year-old man presenting with diffuse alveolar damage due to SARS-CoV-2 infection
Heinrich F, Sperhake J, Heinemann A, Mushumba H, Lennartz M, Nörz D, Glatzel M, Lütgehetmann M, Püschel K
VIRCHOWS ARCH. 2020;477(3):335-339.

Poji:a Fiji-based tool for analysis of podosomes and associated proteins
Herzog R, van den Dries K, Cervero P, Linder S
J CELL SCI. 2020;133(8):.

Efficacy of antiseptic impregnation of aortic endografts with rifampicin compared to silver against in vitro contamination with four bacteria that frequently cause vascular graft infections
Honig S, Seeger P, Rohde H, Kölbel T, Debus E, Diener H
JVS-vascular science. 2020;1:181-189.

Significance of Anti-Nuclear Antibodies and Cryoglobulins in Patients with Acute and Chronic HEV Infection
Horvatits T, Schulze Zur Wiesch J, Polywka S, Buescher G, Lütgehetmann M, Hussey E, Horvatits K, Peine S, Haag F, Addo M, Lohse A, Weiler-Normann C, Pischke S
PATHOGENS. 2020;9(9):.

No link between male infertility and HEV genotype 3 infection
Horvatits T, Varwig-Janssen D, Schulze Zur Wiesch J, Lübke R, Reucher S, Frerk S, Addo M, Schneider S, Lohse A, Luetgehetmann M, Pischke S
GUT. 2020;69(6):1150-1151.

Clinical characteristics and outcomes of invasive Lomentospora prolificans infections: Analysis of patients in the FungiScope® registry
Jenks J, Seidel D, Cornely O, Chen S, van Hal S, Kauffman C, Miceli M, Heinemann M, Christner M, Jover Sáenz A, Burchardt A, Kemmerling B, Herbrecht R, Steinmann J, Shoham S, Gräber S, Pagano L, Deeren D, Slavin M, Hoenigl M
MYCOSES. 2020;63(5):437-442.

Voriconazole plus terbinafine combination antifungal therapy for invasive Lomentospora prolificans infections: analysis of 41 patients from the FungiScope® registry 2008-2019
Jenks J, Seidel D, Cornely O, Chen S, van Hal S, Kauffman C, Miceli M, Heinemann M, Christner M, Sáenz A, Burchardt A, Kemmerling B, Herbrecht R, Steinmann J, Shoham S, Gräber S, Pagano L, Deeren D, Aslam S, Taplitz R, Revankar S, Baddley J, Mehta S, Reed S, Slavin M, Hoenigl M
CLIN MICROBIOL INFEC. 2020;26(6):784.e1-784.e5.

Targeting Endothelial Dysfunction in Eight Extreme-Critically Ill Patients with COVID-19 Using the Anti-Adrenomedullin Antibody Adrecizumab (HAM8101)
Karakas M, Jarczak D, Becker M, Roedl K, Addo M, Hein F, Bergmann A, Zimmermann J, Simon T, Marx G, Lütgehetmann M, Nierhaus A, Kluge S
BIOMOLECULES. 2020;10(8):.

Der erste COVID-19-Hotspot in einer Hamburger Senioreneinrichtung: Präventionskonzept, Letalität und Obduktionsbefunde
Klein A, Edler C, Fitzek A, Fröb D, Heinemann A, Meißner K, Mushumba H, Püschel K, Schröder A, Sperhake J, Ishorst-Witte F, Aepfelbacher M, Heinrich F
RECHTSMEDIZIN. 2020;30(5):325-331.

Pathogen-induced tissue-resident memory TH17 (TRM17) cells amplify autoimmune kidney disease
Krebs C, Reimers D, Zhao Y, Paust H, Bartsch P, Nuñez S, Rosemblatt M, Hellmig M, Kilian C, Borchers A, Enk L, Zinke M, Becker M, Schmid J, Klinge S, Wong M, Puelles V, Schmidt C, Bertram T, Stumpf N, Hoxha E, Meyer-Schwesinger C, Lindenmeyer M, Cohen C, Rink M, Kurts C, Franzenburg S, Koch-Nolte F, Turner J, Riedel J, Huber S, Gagliani N, Huber T, Wiech T, Rohde H, Bono M, Bonn S, Panzer U, Mittrücker H
SCI IMMUNOL. 2020;5(50):.

The podosome cap: past, present, perspective
Linder S, Cervero P
EUR J CELL BIOL. 2020;99(5):151087.

Sustained response after remdesivir and convalescent plasma therapy in a B-cell depleted patient with protracted COVID-19
Malsy J, Veletzky L, Heide J, Hennigs A, Gil-Ibanez I, Stein A, Lütgehetmann M, Rosien U, Jasper D, Peine S, Hiller J, Haag F, Schmiedel S, Huber S, Jordan S, Addo M, Schulze Zur Wiesch J
CLIN INFECT DIS. 2020;73(11):e4020–e4024.

Major central nervous system complications after allogeneic stem cell transplantation: a large retrospective study on 888 consecutive adult patients
Mannina D, Berneking L, Both A, Timm W, Urbanowicz T, Wolschke C, Ayuk F, Fischer N, Fiehler J, Grzyska U, Rösner S, Choe C, Kröger N, Christopeit M
EUR J HAEMATOL. 2020;105(6):722-730.

Neuropathology of patients with COVID-19 in Germany: a post-mortem case series
Matschke J, Lütgehetmann M, Hagel C, Sperhake J, Schröder A, Edler C, Mushumba H, Fitzek A, Allweiss L, Dandri M, Dottermusch M, Heinemann A, Pfefferle S, Schwabenland M, Sumner Magruder D, Bonn S, Prinz M, Gerloff C, Püschel K, Krasemann S, Aepfelbacher M, Glatzel M
LANCET NEUROL. 2020;19(11):919-929.

Clinical evaluation of a SARS-CoV-2 RT-PCR assay on a fully automated system for rapid on-demand testing in the hospital setting
Nörz D, Fischer N, Schultze A, Kluge S, Mayer-Runge U, Aepfelbacher M, Pfefferle S, Lütgehetmann M
J CLIN VIROL. 2020;128:104390.

Pushing beyond specifications:Evaluation of linearity and clinical performance of the cobas 6800/8800 SARS-CoV-2 RT-PCR assay for reliable quantification in blood and other materials outside recommendations
Nörz D, Frontzek A, Eigner U, Oestereich L, Wichmann D, Kluge S, Fischer N, Aepfelbacher M, Pfefferle S, Lütgehetmann M
J CLIN VIROL. 2020;132:104650.

Nucleobindin-1 regulates ECM degradation by promoting intra-Golgi trafficking of MMPs
Pacheco-Fernandez N, Pakdel M, Blank B, Sanchez-Gonzalez I, Weber K, Tran M, Hecht T, Gautsch R, Beck G, Perez F, Hausser A, Linder S, von Blume J
J CELL BIOL. 2020;219(8):.

Implementation of the FilmArray ME panel in laboratory routine using a simple sample selection strategy for diagnosis of meningitis and encephalitis
Pfefferle S, Christner M, Aepfelbacher M, Lütgehetmann M, Rohde H
BMC INFECT DIS. 2020;20(1):170.

Complete Genome Sequence of a SARS-CoV-2 Strain Isolated in Northern Germany
Pfefferle S, Huang J, Nörz D, Indenbirken D, Lütgehetmann M, Oestereich L, Günther T, Grundhoff A, Aepfelbacher M, Fischer N
MICROBIOL RESOUR ANN. 2020;9(23):.

Evaluation of a quantitative RT-PCR assay for the detection of the emerging coronavirus SARS-CoV-2 using a high throughput system
Pfefferle S, Reucher S, Nörz D, Lütgehetmann M
EUROSURVEILLANCE. 2020;25(9):.

Clinical evaluation of five different automated SARS-CoV-2 serology assays in a cohort of hospitalized COVID-19 patients
Pflüger L, Bannasch J, Brehm T, Pfefferle S, Hoffmann A, Nörz D, van der Meirschen M, Kluge S, Haddad M, Pischke S, Hiller J, Addo M, Lohse A, Wiesch J, Peine S, Aepfelbacher M, Lütgehetmann M
J CLIN VIROL. 2020;130:104549.

Multiorgan and Renal Tropism of SARS-CoV-2
Puelles V, Lütgehetmann M, Lindenmeyer M, Sperhake J, Wong M, Allweiss L, Chilla S, Heinemann A, Wanner N, Liu S, Braun F, Lu S, Pfefferle S, Schröder A, Edler C, Gross O, Glatzel M, Wichmann D, Wiech T, Kluge S, Pueschel K, Aepfelbacher M, Huber T
NEW ENGL J MED. 2020;383(6):590-592.

Von den Toten lernen - neue Erkenntnisse zu Covid-19
Püschel K, Kluge S, Addo M, Aepfelbacher M
Hamb Ärztebl. 2020;73(06):34-36.

Fatal renal mucormycosis with Apophysomyces elegans in an apparently healthy male
Rashid S, Ben Abid F, Babu S, Christner M, Alobaidly A, Al Ansari A, Akhtar M
AGING MALE. 2020;23(5):746-749.

Mütter-Screening in einem COVID-19-Niedrig-Pandemiegebiet: Bestimmung SARS-CoV-2-spezifischer Antikörper bei 401 Rostocker Müttern mittels ELISA und Immunfluoreszenz-Bestätigungstest
Reisinger E, von Possel R, Warnke P, Geerdes-Fenge H, Hemmer C, Pfefferle S, Löbermann M, Littmann M, Emmerich P
DEUT MED WOCHENSCHR. 2020;145(17):e96-e100.

PVAmpliconFinder: a workflow for the identification of human papillomaviruses from high-throughput amplicon sequencing
Robitaille A, Brancaccio R, Dutta S, Rollison D, Leja M, Fischer N, Grundhoff A, Gheit T, Tommasino M, Olivier M
BMC BIOINFORMATICS. 2020;21(1):233.

Monocenter study on epidemiology, outcomes, and risk factors of infections in recipients of 166 allogeneic stem cell transplantations during 1 year
Samek M, Iversen K, Belmar Campos C, Berneking L, Langebrake C, Wolschke C, Ayuk F, Kröger N, Christopeit M
EUR J HAEMATOL. 2020;105(2):126-137.

Epidemiology, clinical characteristics, and outcome of candidemia in critically ill patients in Germany: a single-center retrospective 10-year analysis
Schroeder M, Weber T, Denker T, Winterland S, Wichmann D, Rohde H, Ozga A, Fischer M, Kluge S
ANN INTENSIVE CARE. 2020;10(1):142.

Merkel Cell Polyomavirus DNA Replication Induces Senescence in Human Dermal Fibroblasts in a Kap1/Trim28-Dependent Manner
Siebels S, Czech-Sioli M, Spohn M, Schmidt C, Theiss J, Indenbirken D, Günther T, Grundhoff A, Fischer N
MBIO. 2020;11(2):.

Hepatitis Delta Virus Acts as an Immunogenic Adjuvant in Hepatitis B Virus-Infected Hepatocytes
Tham C, Kah J, Tan A, Volz T, Chia A, Giersch K, Ladiges Y, Loglio A, Borghi M, Sureau C, Lampertico P, Lütgehetmann M, Dandri-Petersen M, Bertoletti A
CELL REP MED. 2020;1(4):100060.

Modulation of S. epidermidis-induced innate immune responses in neonatal whole blood
Tröger B, Heidemann M, Osthues I, Knaack D, Göpel W, Herting E, Knobloch J, Härtel C
J MICROBIOL IMMUNOL. 2020;53(2):240-249.

Implications of SARS-CoV-2 Infection and COVID-19 Crisis on Clinical Cancer Care: Report of the University Cancer Center Hamburg: Report of the University Cancer Center Hamburg
Weisel K, Morgner-Miehlke A, Petersen C, Fiedler W, Block A, Schafhausen P, Knobloch J, Bokemeyer C
ONCOL RES TREAT. 2020;43(6):307-313.

Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: A Prospective Cohort Study
Wichmann D, Sperhake J, Lütgehetmann M, Steurer S, Edler C, Heinemann A, Heinrich F, Mushumba H, Kniep I, Schröder A, Burdelski C, de Heer G, Nierhaus A, Frings D, Pfefferle S, Becker H, Bredereke-Wiedling H, de Weerth A, Paschen H, Sheikhzadeh-Eggers S, Stang A, Schmiedel S, Bokemeyer C, Addo M, Aepfelbacher M, Püschel K, Kluge S
ANN INTERN MED. 2020;173(4):268-277.

Molecular Characterization of Staphylococcus aureus Isolated from Chronic Infected Wounds in Rural Ghana
Wolters M, Frickmann H, Christner M, Both A, Rohde H, Oppong K, Akenten C, May J, Dekker D
MICROORGANISMS. 2020;8(12):.

Antibiotic Resistance and Mobile Genetic Elements in Extensively Drug-Resistant Klebsiella pneumoniae Sequence Type 147 Recovered from Germany
Xanthopoulou K, Carattoli A, Wille J, Biehl L, Rohde H, Farowski F, Krut O, Villa L, Feudi C, Seifert H, Higgins P
ANTIBIOTICS-BASEL. 2020;9(10):.

DAMIAN an open source bioinformatics tool for fast, systematic and cohort based analysis of microorganisms in diagnostic samples
Alawi M, Burkhardt L, Indenbirken D, Reumann K, Christopeit M, Kröger N, Lütgehetmann M, Aepfelbacher M, Fischer N, Grundhoff A
SCI REP-UK. 2019;9(1):16841.

Influence of local epidemiology on the performance of common colistin drug susceptibility testing methods
Asar L, Pfefferle S, Lütgehetmann M, Hoffmann A, Katchanov J, Aepfelbacher M, Rohde H, Maurer F
PLOS ONE. 2019;14(6):e0217468.

Further characterization of bovine hepacivirus: Antibody response, course of infection, and host tropism
Baechlein C, Baron A, Meyer D, Gorriz-Martin L, Pfankuche V, Baumgärtner W, Polywka S, Peine S, Fischer N, Rehage J, Becher P
TRANSBOUND EMERG DIS. 2019;66(1):195-206.

General Assembly, Research Caveats:Proceedings of International Consensus on Orthopedic Infections
Bargon R, Bruenke J, Carli A, Fabritius M, Goel R, Goswami K, Graf P, Groff H, Grupp T, Malchau H, Mohaddes M, Novaes de Santana C, Phillips K, Rohde H, Rolfson O, Rondon A, Schaer T, Sculco P, Svensson K
J ARTHROPLASTY. 2019;34(2S):S245-S253.e1.

Tandem Affinity Purification of SBP-CBP-tagged Type Three Secretion System Effectors
Berneking L, Schnapp M, Nauth T, Hentschke M
BIO-PROTOCOL. 2019;9(12):.

Usability of rectal swabs for microbiome sampling in a cohort study of hematological and oncological patients
Biehl L, Garzetti D, Farowski F, Ring D, Koeppel M, Rohde H, Schafhausen P, Stecher B, Vehreschild M
PLOS ONE. 2019;14(4):e0215428.

Impact of single-room contact precautions on hospital-acquisition and transmission of multidrug-resistant Escherichia coli: a prospective multicentre cohort study in haematological and oncological wards
Biehl L, Higgins P, Wille T, Peter K, Hamprecht A, Peter S, Dörfel D, Vogel W, Häfner H, Lemmen S, Panse J, Rohde H, Klupp E, Schafhausen P, Imirzalioglu C, Falgenhauer L, Salmanton-García J, Stecher M, Vehreschild J, Seifert H, Vehreschild M
CLIN MICROBIOL INFEC. 2019;25(8):1013-1020.

Clostridium difficile infection after pediatric solid organ transplantation: a practical single-center experience
Breuer C, Döring S, Rohde H, Rutkowski S, Müller I, Oh J
PEDIATR NEPHROL. 2019;34(7):1269-1275.

Insufficient sensitivity of laser desorption-time of flight mass spectrometry-based detection of hemozoin for malaria screening
Christner M, Frickmann H, Klupp E, Rohde H, Kono M, Tannich E, Poppert S
J MICROBIOL METH. 2019;160:104-106.

Rifamycin derivatives active against pathogenic rapidly-growing mycobacteria
Combrink K, Ramos A, Spring S, Schmidl S, Elizondo K, Morin P, De Jesus B, Maurer F
BIOORG MED CHEM LETT. 2019;29(16):2112-2115.

Controlling intestinal colonization of high-risk haematology patients with ESBL-producing Enterobacteriaceae: a randomized, placebo-controlled, multicentre, Phase II trial (CLEAR)
Dimitriou V, Biehl L, Hamprecht A, Vogel W, Dörfel D, Peter S, Schafhausen P, Rohde H, von Lilienfeld-Toal M, Klassert T, Slickers P, Ehricht R, Slevogt H, Christ H, Hellmich M, Farowski F, Tsakmaklis A, Higgins P, Seifert H, Vehreschild M
J ANTIMICROB CHEMOTH. 2019;74(7):2065-2074.

Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation
Dondelinger Y, Delanghe T, Priem D, Wynosky-Dolfi M, Sorobetea D, Rojas-Rivera D, Giansanti P, Roelandt R, Gropengiesser J, Ruckdeschel K, Savvides S, Heck A, Vandenabeele P, Brodsky I, Bertrand M
NAT COMMUN. 2019;10(1):1729.

Extended-spectrum β-lactamase-producing Enterobacteriaceae among geckos (Hemidactylus brookii) in a Ghanaian hospital
Eibach D, Nagel M, Lorenzen S, Hogan B, Belmar Campos C, Aepfelbacher M, Sarpong N, May J
CLIN MICROBIOL INFEC. 2019;25(8):1048-1050.

Clinical evaluation of multiplex RT-PCR assays for the detection of influenza A/B and respiratory syncytial virus using a high throughput system
Eigner U, Reucher S, Hefner N, Staffa-Peichl S, Kolb M, Betz U, Holfelder M, Spier G, Pfefferle S, Lütgehetmann M
J VIROL METHODS. 2019;269:49-54.

Piscine Orthoreovirus 3 Is Not the Causative Pathogen of Proliferative Darkening Syndrome (PDS) of Brown Trout ()
Fux R, Arndt D, Langenmayer M, Schwaiger J, Ferling H, Fischer N, Indenbirken D, Grundhoff A, Dölken L, Adamek M, Steinhagen D, Sutter G
VIRUSES-BASEL. 2019;11(2):.

Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo
Giersch K, Bhadra O, Volz T, Allweiss L, Riecken K, Fehse B, Lohse A, Petersen J, Sureau C, Urban S, Dandri M, Lütgehetmann M
GUT. 2019;68(1):150-157.

Microbial findings, sensitivity and outcome in patients with postoperative peritonitis a retrospective cohort study
Grotelueschen R, Luetgehetmann M, Erbes J, Heidelmann L, Grupp K, Karstens K, Ghadban T, Reeh M, Izbicki J, Bachmann K
INT J SURG. 2019;70:63-69.

T-lymphocyte-specific knockout of IKK-2 or NEMO induces T17 cells in an experimental nephrotoxic nephritis mouse model
Guo L, Huang J, Chen M, Piotrowski E, Song N, Zahner G, Paust H, Alawi M, Geffers R, Thaiss F
FASEB J. 2019;33(2):2359-2371.

The Clinical Perspective on Hepatitis E
Horvatits T, Schulze Zur Wiesch J, Lütgehetmann M, Lohse A, Pischke S
VIRUSES-BASEL. 2019;11(7):.

The Challenge of Post-Mortem GHB Analysis: Storage Conditions and Specimen Types Are Both Important
Kietzerow J, Otto B, Wilke N, Rohde H, Iwersen-Bergmann S, Andresen-Streichert H
INT J LEGAL MED. 2019;2019:205-215.

SNX3 drives maturation of Borrelia phagosomes by forming a hub for PI(3)P, Rab5a, and galectin-9
Klose M, Salloum J, Gonschior H, Linder S
J CELL BIOL. 2019;218(9):3039-3059.

Nrf2 Sequesters Keap1 Preventing Podosome Disassembly:A Quintessential Duet Moonlights in Endothelium
Kloska D, Kopacz A, Cysewski D, Aepfelbacher M, Dulak J, Jozkowicz A, Grochot-Przeczek A
ANTIOXID REDOX SIGN. 2019;30(14):1709-1730.

Hygienemanagement - Implementierung in Organisation und Prozesse
Knobloch J
2019. Pflegemanagement. Prölß J, Lux V, Bechtel P (Hrsg.). 1. Aufl. Berlin: Mwv Medizinisch Wissenschaftliche Verlagsges, 399-402.

New World Health Organization Treatment Recommendations for Multidrug-Resistant Tuberculosis:Are We Well Enough Prepared?
Kranzer K, Kalsdorf B, Heyckendorf J, Andres S, Merker M, Hofmann-Thiel S, Bloemberg G, Hoffmann H, Niemann S, Lange C, Maurer F
AM J RESP CRIT CARE. 2019;200(4):514-515.

Changes in the composition of the upper respiratory tract microbial community in granulomatosis with polyangiitis
Lamprecht P, Fischer N, Huang J, Burkhardt L, Lütgehetmann M, Arndt F, Rolfs I, Kerstein A, Iking-Konert C, Laudien M
J AUTOIMMUN. 2019;97:29-39.

Detection of a Broad Range of Low-Level Major Histocompatibility Complex Class II-Restricted, Hepatitis Delta Virus (HDV)-Specific T-Cell Responses Regardless of Clinical Status
Landahl J, Bockmann J, Scheurich C, Ackermann C, Matzat V, Heide J, Nuurei T, D'Antonio G, von Felden J, Sette A, Peine S, Lohse A, Lütgehetmann M, Marget M, Sidney J, Schulze Zur Wiesch J
J INFECT DIS. 2019;219(4):568-577.

Combined culture and metagenomic analyses reveal significant shifts in the composition of the cutaneous microbiome in psoriasis
Langan E, Künstner A, Miodovnik M, Zillikens D, Thaçi D, Baines J, Ibrahim S, Solbach W, Knobloch J
BRIT J DERMATOL. 2019;181(6):1254-1264.

Initial therapy affects duration of diarrhoea in critically ill patients with Clostridioides difficile infection (CDI)
Manthey C, Dranova D, Christner M, Drolz A, Kluge S, Lohse A, Fuhrmann V
CRIT CARE. 2019;23(1):399.

Invasive pulmonale Aspergillose
Matthews H, Rohde H, Wichmann D, Kluge S
DEUT MED WOCHENSCHR. 2019;144(17):1218-1222.

Potential Role for Urine Polymerase Chain Reaction in the Diagnosis of Whipple's Disease
Moter A, Janneck M, Wolters M, Iking-Konert C, Wiessner A, Loddenkemper C, Hartleben B, Lütgehetmann M, Schmidt J, Langbehn U, Janssen S, Geelhaar-Karsch A, Schneider T, Moos V, Rohde H, Kikhney J, Wiech T
CLIN INFECT DIS. 2019;68(7):1089-1097.

Potential Role for Urine Polymerase Chain Reaction in the Diagnosis of Whipple Disease: Reply to Tison and Saraux
Moter A, Kikhney J, Moos V, Wiech T, Rohde H, Wolters M
CLIN INFECT DIS. 2019;69(5):905.

Implementation of a multidisciplinary infections conference affects the treatment plan in prosthetic joint infections of the hip:a retrospective study
Ntalos D, Berger-Groch J, Rohde H, Grossterlinden L, Both A, Luebke A, Hartel M, Klatte T
ARCH ORTHOP TRAUM SU. 2019;139(4):467-473.

Chronic Hepatitis E in Rheumatology and Internal Medicine Patients: A Retrospective Multicenter European Cohort Study
Pischke S, Peron J, von Wulffen M, von Felden J, Höner Zu Siederdissen C, Fournier S, Lütgehetmann M, Iking-Konert C, Bettinger D, Par G, Thimme R, Cantagrel A, Lohse A, Wedemeyer H, de Man R, Mallet V
VIRUSES-BASEL. 2019;11(2):.

Detection and Characterization of Circulating Tumor Cells in Patients with Merkel Cell Carcinoma
Riethdorf S, Hildebrandt L, Heinzerling L, Heitzer E, Fischer N, Bergmann S, Mauermann O, Waldispühl-Geigl J, Coith C, Schön G, Peine S, Schuler G, Speicher M, Moll I, Pantel K
CLIN CHEM. 2019;65(3):462-472.

Identification of a novel clade of group A rotaviruses in fatally diseased domestic pigeons in Europe
Rubbenstroth D, Peus E, Schramm E, Kottmann D, Bartels H, McCowan C, Schulze C, Akimkin V, Fischer N, Wylezich C, Hlinak A, Spadinger A, Großmann E, Petersen H, Grundhoff A, Rautenschlein S, Teske L
TRANSBOUND EMERG DIS. 2019;66(1):552-561.

2018 international consensus meeting on musculoskeletal infection: Summary from the Biofilm Workgroup and consensus on Biofilm related Musculoskeletal Infections
Saeed K, McLaren A, Schwarz E, Antoci V, Arnold W, Chen A, Clauss M, Esteban J, Gant V, Hendershot E, Hickok N, Higuera C, Coraça-Huber D, Choe H, Jennings J, Joshi M, Li W, Noble P, Phillips K, Pottinger P, Restrepo C, Rohde H, Schaer T, Shen H, Smeltzer M, Stoodley P, Webb J, Witsø E
J ORTHOP RES. 2019;37(5):1007-1017.

Differences in Shedding of the Interleukin-11 Receptor by the Proteases ADAM9, ADAM10, ADAM17, Meprin α, Meprin β and MT1-MMP
Sammel M, Peters F, Lokau J, Scharfenberg F, Werny L, Linder S, Garbers C, Rose-John S, Becker-Pauly C
INT J MOL SCI. 2019;20(15):.

Fatal PCR-negative herpes simplex virus-1 encephalitis with GABAA receptor antibodies
Schuster S, Abrante L, Matschke J, Lütgehetmann M, Holst B, Gelderblom M, Braass H, Leypoldt F, Magnus T
NEUROL-NEUROIMMUNOL. 2019;6(6):.

Was tun nach dem Stich? Verletzungen mit Infektionsrisiko
Stranzinger J, Wunderle W, Nienhaus A, Kaiser B, Steinmann J, Polywka S
Deutsches Ärzteblatt. 2019;116(14):690-92.

Stridor From a Concealed Perforated Aortic Aneurysm
Tanida K
DTSCH ARZTEBL INT. 2019.

Chronic equine hepacivirus infection in an adult gelding with severe hepatopathy
Tegtmeyer B, Echelmeyer J, Pfankuche V, Puff C, Todt D, Fischer N, Durham A, Feige K, Baumgärtner W, Steinmann E, Cavalleri J
VET MED SCI. 2019;5(3):372-378.

Activation of the macroautophagy pathway by Yersinia enterocolitica promotes intracellular multiplication and egress of yersiniae from epithelial cells
Valencia Lopez M, Schimmeck H, Gropengießer J, Middendorf L, Quitmann M, Schneider C, Holstermann B, Wacker R, Heussler V, Reimer R, Aepfelbacher M, Ruckdeschel K
CELL MICROBIOL. 2019;21(9):e13046.

Probing the mechanical landscape - new insights into podosome architecture and mechanics
van den Dries K, Linder S, Maridonneau-Parini I, Poincloux R
J CELL SCI. 2019;132(24):.

T cell receptor grafting allows virological control of Hepatitis B virus infection
Wisskirchen K, Kah J, Malo A, Asen T, Volz T, Allweiss L, Wettengel J, Lütgehetmann M, Urban S, Bauer T, Dandri M, Protzer U
J CLIN INVEST. 2019;129(7):2932-2945.

Novel Human Polyomavirus Noncoding Control Regions Differ in Bidirectional Gene Expression according to Host Cell, Large T-Antigen Expression, and Clinically Occurring Rearrangements
Ajuh E, Wu Z, Kraus E, Weissbach F, Bethge T, Gosert R, Fischer N, Hirsch H
J VIROL. 2018;92(7):e02231-17.

Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo
Allweiss L, Volz T, Giersch K, Kah J, Raffa G, Petersen J, Lohse A, Beninati C, Pollicino T, Urban S, Lütgehetmann M, Dandri M
GUT. 2018;67(3):542-552.

Epidemiology, biology and therapy of Merkel cell carcinoma:conclusions from the EU project IMMOMEC
Becker J, Stang A, Hausen A, Fischer N, DeCaprio J, Tothill R, Lyngaa R, Hansen U, Ritter C, Nghiem P, Bichakjian C, Ugurel S, Schrama D
CANCER IMMUNOL IMMUN. 2018;67(3):341-351.

Growth of Cutibacterium acnes is common on osteosynthesis material of the shoulder in patients without signs of infection
Both A, Klatte T, Lübke A, Büttner H, Hartel M, Grossterlinden L, Rohde H
ACTA ORTHOP. 2018;89(5):580-584.

Generation of a novel next-generation sequencing-based method for the isolation of new human papillomavirus types
Brancaccio R, Robitaille A, Dutta S, Cuenin C, Santare D, Skenders G, Leja M, Fischer N, Giuliano A, Rollison D, Grundhoff A, Tommasino M, Gheit T
VIROLOGY. 2018;520:1-10.

Epidemiology, clinical and laboratory features of 24 consecutive cases of leptospirosis at a German infectious disease center.
Brehm T, Schulze zur Wiesch J, Lütgehetmann M, Tappe D, Eisermann P, Lohse A, Addo M, Schmiedel S
INFECTION. 2018;46(6):847-853.

Multicenter assessment of the rapid Unyvero Blood Culture molecular assay
Burrack-Lange S, Personne Y, Huber M, Winkler E, Weile J, Knabbe C, Görig J, Rohde H
J MED MICROBIOL. 2018;67(9):1294-1301.

Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells
Cabron A, El Azzouzi K, Boss M, Arnold P, Schwarz J, Rosas M, Dobert J, Pavlenko E, Schumacher N, Renné T, Taylor P, Linder S, Rose-John S, Zunke F
J IMMUNOL. 2018;201(10):3106-3118.

Lymphocyte-specific protein 1 regulates mechanosensory oscillation of podosomes and actin isoform-based actomyosin symmetry breaking
Cervero P, Wiesner C, Bouissou A, Poincloux R, Linder S
NAT COMMUN. 2018;9(1):515.

Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in local and imported poultry meat in Ghana
Eibach D, Dekker D, Gyau Boahen K, Wiafe Akenten C, Sarpong N, Belmar Campos C, Berneking L, Aepfelbacher M, Krumkamp R, Owusu-Dabo E, May J
VET MICROBIOL. 2018;217:7-12.

Comparison of PapilloCheck and Linear Array to Detect and Differentiate Human Papillomaviruses in Cervical and Tonsillar Smears from Females with Cervical Intraepithelial Lesions
Grimm D, Woelber L, Prieske K, Schmalfeldt B, Kürti S, Busch C, Teudt I, Brummer O, Mueller V, Meyer T
EUR J MICROBIOL IMMU. 2018;8(4):107-111.

S2k guideline: HPV-associated lesions of the external genital region and the anus - anogenital warts and precancerous lesions of the vulva, the penis, and the peri- and intra-anal skin (short version)
Gross G, Werner R, Becker J, Brockmeyer N, Esser S, Hampl M, Hommel S, Jongen J, Mestel D, Meyer T, Petry K, Plettenberg A, Püschel K, Schneede P, Schöfer H, Sotlar K, Weyandt G, Wieland U, Wiese-Posselt M, Nast A
J DTSCH DERMATOL GES. 2018;16(2):242-255.

Hepatitis E seroprevalence in the Americas: A systematic review and meta-analysis
Horvatits T, Ozga A, Westhölter D, Hartl J, Manthey C, Lütgehetmann M, Rauch G, Kriston L, Lohse A, Bendall R, Wedemeyer H, Dalton H, Pischke S
LIVER INT. 2018;38(11):1951-1964.

Lack of evidence for human serum albumin as major source of HEV infections
Horvatits T, Westhölter D, Peine S, Schulze Zur Wiesch J, Lohse A, Lütgehetmann M, Pischke S
TRANSFUSION MED. 2018;28(6):470-471.

Carbapenem-resistant Gram-negative pathogens in a German university medical Center: Prevalence, clinical implications and the role of novel β-lactam/β-lactamase inhibitor combinations
Katchanov J, Asar L, Klupp E, Both A, Rothe C, König C, Rohde H, Kluge S, Maurer F
PLOS ONE. 2018;13(4):e0195757.

Efficacy of NVR 3-778, Alone and in Combination With Pegylated Interferon, vs Entecavir in uPA/SCID Mice With Humanized Livers and HBV Infection
Klumpp K, Shimada T, Allweiss L, Volz T, Lütgehetmann M, Hartman G, Flores O, Lam A, Dandri-Petersen M
GASTROENTEROLOGY. 2018;154(3):652-662.e8.

Course of HEV viremia and anti-HEV IgM/IgG response in asymptomatic blood donors
Kraef C, Schlein C, Hiller J, Westhölter D, Denzer U, Horvatits T, Peine S, Lohse A, Lütgehetmann M, Polywka S, Pischke S
J CLIN VIROL. 2018;105:26-30.

Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides
Lamprecht P, Kerstein A, Klapa S, Schinke S, Karsten C, Yu X, Ehlers M, Epplen J, Holl-Ulrich K, Wiech T, Kalies K, Lange T, Laudien M, Laskay T, Gemoll T, Schumacher U, Ullrich S, Busch H, Ibrahim S, Fischer N, Hasselbacher K, Pries R, Petersen F, Weppner G, Manz R, Humrich J, Nieberding R, Riemekasten G, Müller A
FRONT IMMUNOL. 2018;9:680.

The role of the microbiome in Psoriasis: moving from disease description to treatment selection?
Langan E, Griffiths C, Solbach W, Knobloch J, Zillikens D, Thaçi D
BRIT J DERMATOL. 2018;178(5):1020-1027.

Stool cultures at the ICU: get rid of it!
Manthey C, Dranova D, Christner M, Berneking L, Kluge S, Lohse A, Fuhrmann V
ANN INTENSIVE CARE. 2018;8(1):10.

Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3 Regulatory T Cells
Mathies F, Steffens N, Kleinschmidt D, Stuhlmann F, Huber F, Roy U, Meyer T, Luetgehetmann M, von Petersdorff M, Seiz O, Herkel J, Schramm C, Flavell R, Gagliani N, Krebs C, Panzer U, Abdullah Z, Strowig T, Bedke T, Huber S
J IMMUNOL. 2018;201(12):3558-3568.

To die or not to die:Regulatory feedback phosphorylation circuits determine receptor-interacting protein kinase-1 (RIPK1) function
Menon M, Gropengießer J, Ruckdeschel K, Gaestel M
MOL CELL ONCOL. 2018;5(1):e1396389.

Disease-associated genotypes of the commensal skin bacterium Staphylococcus epidermidis
Méric G, Mageiros L, Pensar J, Laabei M, Yahara K, Pascoe B, Kittiwan N, Tadee P, Post V, Lamble S, Bowden R, Bray J, Morgenstern M, Jolley K, Maiden M, Feil E, Didelot X, Miragaia M, de Lencastre H, Moriarty T, Rohde H, Massey R, Mack D, Corander J, Sheppard S
NAT COMMUN. 2018;9:5034.

A Novel Orally Available Small Molecule That Inhibits Hepatitis B Virus Expression
Mueller H, Wildum S, Luangsay S, Walther J, Lopez A, Tropberger P, Ottaviani G, Lu W, John Parrott N, Zhang J, Schmucki R, Racek T, Hoflack J, Kueng E, Point F, Zhou X, Steiner G, Lütgehetmann M, Rapp G, Volz T, Dandri M, Yang S, Young J, Javanbakht H
J HEPATOL. 2018;68(3):412-420.

Visualization of translocons in Yersinia type III protein secretion machines during host cell infection
Nauth T, Huschka F, Schweizer M, Bosse J, Diepold A, Failla A, Steffen A, Stradal T, Wolters M, Aepfelbacher M
PLOS PATHOG. 2018;14(12):e1007527.

MT1-MMP targeting to endolysosomes is mediated by upregulation of flotillins
Planchon D, Rios Morris E, Genest M, Comunale F, Vacher S, Bièche I, Denisov E, Tashireva L, Perelmuter V, Linder S, Chavrier P, Bodin S, Gauthier-Rouvière C
J CELL SCI. 2018;131(17):jcs218925.

Incidence of infections due to third generation cephalosporin-resistant - a prospective multicentre cohort study in six German university hospitals
Rohde A, Zweigner J, Wiese-Posselt M, Schwab F, Behnke M, Kola A, Obermann B, Knobloch J, Feihl S, Querbach C, Gebhardt F, Mischnik A, Ihle V, Schröder W, Armean S, Peter S, Tacconelli E, Hamprecht A, Seifert H, Vehreschild M, Kern W, Gastmeier P
ANTIMICROB RESIST IN. 2018;7:159.

Antimicrobial lubricant reduces rectal bacteria at transrectal prostate biopsy:results from a prospective randomized trial
Salomon G, Saul J, Prues S, Schneider M, Budäus L, Tilki D, Rohde H, Haferkamp A, Graefen M, Boehm K
WORLD J UROL. 2018;36(6):871-876.

Clinical relevance of cytoskeleton associated proteins for ovarian cancer
Schiewek J, Schumacher U, Lange T, Joosse S, Wikman H, Pantel K, Mikhaylova M, Kneussel M, Linder S, Schmalfeldt B, Oliveira-Ferrer L, Windhorst S
J CANCER RES CLIN. 2018;144(11):2195-2205.

Ultra-dense polymer brush coating reduces Staphylococcus epidermidis biofilms on medical implants and improves antibiotic treatment outcome
Skovdal S, Jørgensen N, Petersen E, Jensen-Fangel S, Ogaki R, Zeng G, Johansen M, Wang M, Rohde H, Meyer R
ACTA BIOMATER. 2018;76:46-55.

Konsenspapier zur Nachsorge von Stich- und Schnittverletzungen mit infektiösem Material
Stranzinger J, Wunderle W, Dulon M, Nienhaus A, Kaiser B, Steinmann J, Jung S, Polywka S
2018. RiRe - Risiken und Ressourcen in Gesundheitsdienst und Wohlfahrtspflege. Nienhaus A (Hrsg.). 1. Aufl. Landsberg am Lech: 59-78.

Konsenspapier zur Nachsorge von Stich- und Schnittverletzungen mit infektiösem Material – Gemeinsame Empfehlungen der Unfallkassen Baden-Württemberg, Berlin, Nord, Nordrhein-Westfalen und der Berufsgenossenschaft für Gesundheitsdienst und Wohlfahrtspflege
Stranzinger J, Wunderle W, Dulon M, Nienhaus A, Kaiser B, Steinmann J, Jung S, Polywka S
Arbeitsmed Sozialmed Umweltmed. 2018;53(4):248-255.

Hepatitis E: Still Waters Run Deep
von Wulffen M, Westhölter D, Lütgehetmann M, Pischke S
J CLIN TRANSL HEPATO. 2018;6(1):40-47.

Comprehensive Molecular Approach for Characterization of Hepatitis E Virus Genotype 3 Variants
Wang B, Harms D, Papp C, Niendorf S, Jacobsen S, Lütgehetmann M, Pischke S, Wedermeyer H, Hofmann J, Bock C
J CLIN MICROBIOL. 2018;56(5):e01686-17.

HEV-positive blood donations represent a relevant infection risk for immunosuppressed recipients
Westhölter D, Hiller J, Denzer U, Polywka S, Ayuk F, Rybczynski M, Horvatits T, Gundlach S, Blöcker J, Schulze Zur Wiesch J, Fischer N, Addo M, Peine S, Göke B, Lohse A, Lütgehetmann M, Pischke S
J HEPATOL. 2018;69(1):36-42.

Efficacy of introducing a checklist to reduce central venous line associated bloodstream infections in the ICU caring for adult patients
Wichmann D, Belmar Campos C, Ehrhardt S, Kock T, Weber C, Rohde H, Kluge S
BMC INFECT DIS. 2018;18(1):267.

Megahertz serial crystallography
Wiedorn M, Oberthür D, Bean R, Schubert R, Werner N, Abbey B, Aepfelbacher M, Adriano L, Allahgholi A, Al-Qudami N, Andreasson J, Aplin S, Awel S, Ayyer K, Bajt S, Barák I, Bari S, Bielecki J, Botha S, Boukhelef D, Brehm W, Brockhauser S, Cheviakov I, Coleman M, Cruz-Mazo F, Danilevski C, Darmanin C, Doak R, Domaracky M, Dörner K, Du Y, Fangohr H, Fleckenstein H, Frank M, Fromme P, Gañán-Calvo A, Gevorkov Y, Giewekemeyer K, Ginn H, Graafsma H, Graceffa R, Greiffenberg D, Gumprecht L, Göttlicher P, Hajdu J, Hauf S, Heymann M, Holmes S, Horke D, Hunter M, Imlau S, Kaukher A, Kim Y, Klyuev A, Knoška J, Kobe B, Kuhn M, Kupitz C, Küpper J, Lahey-Rudolph J, Laurus T, Le Cong K, Letrun R, Xavier P, Maia L, Maia F, Mariani V, Messerschmidt M, Metz M, Mezza D, Michelat T, Mills G, Monteiro D, Morgan A, Mühlig K, Munke A, Münnich A, Nette J, Nugent K, Nuguid T, Orville A, Pandey S, Pena G, Villanueva-Perez P, Poehlsen J, Previtali G, Redecke L, Riekehr W, Rohde H, Round A, Safenreiter T, Sarrou I, Sato T, Schmidt M, Schmitt B, Schönherr R, Schulz J, Sellberg J, Seibert M, Seuring C, Shelby M, Shoeman R, Sikorski M, Silenzi A, Stan C, Shi X, Stern S, Sztuk-Dambietz J, Szuba J, Tolstikova A, Trebbin M, Trunk U, Vagovic P, Ve T, Weinhausen B, White T, Wrona K, Xu C, Yefanov O, Zatsepin N, Zhang J, Perbandt M, Mancuso A, Betzel C, Chapman H, Barty A
NAT COMMUN. 2018;9(1):4025.

Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection
Winer B, Shirvani-Dastgerdi E, Bram Y, Sellau J, Low B, Johnson H, Huang T, Hrebikova G, Heller B, Sharon Y, Giersch K, Gerges S, Seneca K, Pais M, Frankel A, Chiriboga L, Cullen J, Nahass R, Lutgehetmann M, Toettcher J, Wiles M, Schwartz R, Ploss A
SCI TRANSL MED. 2018;10(447):eaap9328.

Acting on Actin:Rac and Rho Played by Yersinia
Aepfelbacher M, Wolters M
CURR TOP MICROBIOL. 2017;399:201-220.

Immunofluorescent Staining for the Detection of the Hepatitis B Core Antigen in Frozen Liver Sections of Human Liver Chimeric Mice
Allweiss L, Lütgehetmann M, Dandri M
Methods Mol Biol. 2017;1540:135-142.

Biphasic influence of Staphylococcus aureus on human epidermal tight junctions
Bäsler K, Galliano M, Bergmann S, Rohde H, Wladykowski E, Vidal-Y-Sy S, Guiraud B, Houdek P, Schüring G, Volksdorf T, Caruana A, Bessou-Touya S, Schneider S, Duplan H, Brandner J
ANN NY ACAD SCI. 2017;1405(1):53-70.

Screening and contact precautions - A survey on infection control measures for multidrug-resistant bacteria in German university hospitals
Biehl L, Bertz H, Bogner J, Dobermann U, Kessel J, Krämer C, Lemmen S, von Lilienfeld-Toal M, Peter S, Pletz M, Rohde H, Schmiedel S, Schubert S, Ullmann A, Fätkenheuer G, Vehreschild M
ANTIMICROB RESIST IN. 2017;6:37.

Emergence of ceftazidime/avibactam non-susceptibility in an MDR Klebsiella pneumoniae isolate
Both A, Büttner H, Huang J, Perbandt M, Belmar Campos C, Christner M, Maurer F, Kluge S, König C, Aepfelbacher M, Wichmann D, Rohde H
J ANTIMICROB CHEMOTH. 2017;72(9):2483-2488.

Two-tier approach combining molecular and culture-based techniques for optimized detection of vancomycin-resistant enterococci
Both A, Franke G, Mirwald N, Lütgehetmann M, Christner M, Klupp E, Belmar Campos C, Büttner H, Aepfelbacher M, Rohde H
DIAGN MICR INFEC DIS. 2017;89(4):253-257.

The hypomorphic TERT A1062T variant is associated with increased treatment-related toxicity in acute myeloid leukemia
Both A, Krauter J, Damm F, Thol F, Göhring G, Heuser M, Ottmann O, Lübbert M, Wattad M, Kanz L, Schlimok G, Raghavachar A, Fiedler W, Kirchner H, Brugger W, Schlegelberger B, Heil G, Ganser A, Wagner K
ANN HEMATOL. 2017;96(6):895-904.

Complete Genome Sequence of a Novel Human Gammapapillomavirus Isolated from Skin
Brancaccio R, Robitaille A, Dutta S, Rollison D, Fischer N, Grundhoff A, Tommasino M, Gheit T
Genome Announc. 2017;5(34):.

Nramp1 and NrampB Contribute to Resistance against Francisella in Dictyostelium
Brenz Y, Ohnezeit D, Winther-Larsen H, Hagedorn M
FRONT CELL INFECT MI. 2017.

Molecular analysis of the ramRA locus in clinical Klebsiella pneumoniae isolates with reduced susceptibility to tigecycline
Campos C, Aepfelbacher M, Hentschke M
NEW MICROBIOL. 2017;40(2):135-138.

Identification of Shiga-Toxigenic Escherichia coli outbreak isolates by a novel data analysis tool after matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Christner M, Dressler D, Andrian M, Reule C, Petrini O
PLOS ONE. 2017;12(9):e0182962.

Novel poly-uridine insertion in the 3'UTR and E2 amino acid substitutions in a low virulent classical swine fever virus
Coronado L, Liniger M, Muñoz-González S, Postel A, Pérez L, Pérez-Simó M, Perera C, Frías-Lepoureau M, Rosell R, Grundhoff A, Indenbirken D, Alawi M, Fischer N, Becher P, Ruggli N, Ganges L
VET MICROBIOL. 2017;201:103-112.

Phenol-Soluble Modulin Toxins of Staphylococcus haemolyticus
Da F, Joo H, Cheung G, Villaruz A, Rohde H, Luo X, Otto M
FRONT CELL INFECT MI. 2017;7:206.

Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization
Dahlke C, Kasonta R, Lunemann S, Krähling V, Zinser M, Biedenkopf N, Fehling S, Ly M, Rechtien A, Stubbe H, Olearo F, Borregaard S, Jambrecina A, Stahl F, Strecker T, Eickmann M, Lütgehetmann M, Spohn M, Schmiedel S, Lohse A, Becker S, Addo M
EBIOMEDICINE. 2017;19:107-118.

Autoantibodies against "rods and rings"-related IMPDH2 in hepatitis C genotype 1 and DAA therapy in a "real life" cohort
Dammermann W, Polywka S, Dettmann I, Mindorf S, Komorowski L, Wehmeyer M, Schulze Zur Wiesch J, Stöcker W, Lüth S
MED MICROBIOL IMMUN. 2017;206(5):379-382.

Pregnancy-Related Immune Adaptation Promotes the Emergence of Highly Virulent H1N1 Influenza Virus Strains in Allogenically Pregnant Mice
Engels G, Hierweger A, Hoffmann J, Thieme R, Thiele S, Bertram S, Dreier C, Resa-Infante P, Jacobsen H, Thiele K, Alawi M, Indenbirken D, Grundhoff A, Siebels S, Fischer N, Stojanovska V, Muzzio D, Jensen F, Karimi K, Mittrücker H, Arck P, Gabriel G
CELL HOST MICROBE. 2017;21(3):321-333.

Complete Genome Sequence of Staphylococcus epidermidis 1457
Galac M, Stam J, Maybank R, Hinkle M, Mack D, Rohde H, Roth A, Fey P
Genome Announc. 2017;5(22):e00450-17.

Serum HBV pgRNA as a clinical marker for cccDNA activity
Giersch K, Allweiss L, Volz T, Dandri-Petersen M, Lütgehetmann M
J HEPATOL. 2017;66(2):460-462.

Both interferon alpha and lambda can reduce all intrahepatic HDV infection markers in HBV/HDV infected humanized mice
Giersch K, Homs M, Volz T, Helbig M, Allweiss L, Lohse A, Petersen J, Buti M, Pollicino T, Sureau C, Dandri M, Lütgehetmann M
SCI REP-UK. 2017;7(1):3757.

Recovery of the first full-length genome sequence of a parapoxvirus directly from a clinical sample
Günther T, Haas L, Alawi M, Wohlsein P, Marks J, Grundhoff A, Becher P, Fischer N
SCI REP-UK. 2017;7(1):3734.

Comparison of one commercial and two in-house TaqMan multiplex real-time PCR assays for detection of enteropathogenic, enterotoxigenic and enteroaggregative Escherichia coli
Hahn A, Lütgehetmann M, Landt O, Schwarz N, Frickmann H
TROP MED INT HEALTH. 2017;22(11):1371-1376.

Limitations in the use of PSMγ, agr, RNAIII, and biofilm formation as biomarkers to define invasive Staphylococcus epidermidis from chronic biomedical device-associated infections
Harris L, Dudley E, Rohde H, Frommelt L, Siemssen N, Wilkinson T, Mack D
INT J MED MICROBIOL. 2017;307(7):382-387.

Impact of non-transferrin-bound iron (NTBI) in comparison to serum ferritin on outcome after allogeneic stem cell transplantation (ASCT)
Hilken A, Langebrake C, Wolschke C, Kersten J, Rohde H, Nielsen P, Kröger N
ANN HEMATOL. 2017;96(8):1379-1388.

ESGAP inventory of target indicators assessing antibiotic prescriptions: a cross-sectional survey
Howard P, Huttner B, Beovic B, Beraud G, Kofteridis D, Pano Pardo J, Schouten J, Pulcini C
J ANTIMICROB CHEMOTH. 2017 [Epub ahead of print].

Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection
Kah J, Koh S, Volz T, Ceccarello E, Allweiss L, Lütgehetmann M, Bertoletti A, Dandri M
J CLIN INVEST. 2017;127(8):3177-3188.

Heme oxygenase-1 polymorphisms can affect HCV replication and treatment responses with different efficacy in humanized mice
Kah J, Volz T, Lütgehetmann M, Groth A, Lohse A, Tiegs G, Sass G, Dandri-Petersen M
LIVER INT. 2017;37(8):1128-1137.

Risk factors for excessively prolonged meropenem use in the intensive care settinga case-contol study
Katchanov J, Kreuels B, Maurer F, Wöstmann K, Jochum J, König C, Seoudy K, Rohde H, Lohse A, Wichmann D, Baehr M, Rothe C, Kluge S
BMC INFECT DIS. 2017;17(1):131.

Spontaneous lung metastasis formation of human Merkel cell carcinoma cell lines transplanted into scid mice
Knips J, Czech-Sioli M, Spohn M, Heiland M, Moll I, Grundhoff A, Schumacher U, Fischer N
INT J CANCER. 2017;141(1):160-171.

"Life-like" assessment of antimicrobial surfaces by a new touch transfer assay displays strong superiority of a copper alloy compared to silver containing surfaces
Knobloch J, Tofern S, Kunz W, Schütze S, Riecke M, Solbach W, Wuske T
PLOS ONE. 2017;12(11):e0187442.

Case report - atypical hemolytic uremic syndrome triggered by influenza B
Kobbe R, Schild R, Christner M, Oh J, Loos S, Kemper M
BMC NEPHROL. 2017;18(1):96.

Epidemiology of invasive aspergillosis and azole resistance in patients with acute leukaemia:the SEPIA Study
Koehler P, Hamprecht A, Bader O, Bekeredjian-Ding I, Buchheidt D, Doelken G, Elias J, Haase G, Hahn-Ast C, Karthaus M, Kekulé A, Keller P, Kiehl M, Krause S, Krämer C, Neumann S, Rohde H, La Rosée P, Ruhnke M, Schafhausen P, Schalk E, Schulz K, Schwartz S, Silling G, Staib P, Ullmann A, Vergoulidou M, Weber T, Cornely O, Vehreschild M
INT J ANTIMICROB AG. 2017;49(2):218-223.

Arp2/3:Not Absolutely Required After All?
Linder S
DEV CELL. 2017;42(5):436-438.

Advances in Rapid Identification and Susceptibility Testing of Bacteria in the Clinical Microbiology Laboratory:Implications for Patient Care and Antimicrobial Stewardship Programs
Maurer F, Christner M, Hentschke M, Rohde H
INFECT DIS REP. 2017;9(1):6839.

Neue mikrobiologische Diagnostikverfahren: Chancen und Limitierungen
Maurer F, Hentschke M, Rohde H
MED KLIN-INTENSIVMED. 2017;112(3):199-205.

p38(MAPK)/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection
Menon M, Gropengießer J, Fischer J, Novikova L, Deuretzbacher A, Lafera J, Schimmeck H, Czymmeck N, Ronkina N, Kotlyarov A, Aepfelbacher M, Gaestel M, Ruckdeschel K
NAT CELL BIOL. 2017;19(10):1248-1259.

Schnelltest-Diagnostik sexuell übertragbarer Infektionen in niedrigschwelligen Einrichtungen: Gemeinsame Stellungnahme des RKI, PEI und der DSTIG
Meyer T, Schüttler C, Straube E, Roß R, Stürmer M, Jansen K, Buder S, Nick S, Hagedorn H, Bremer V, Brockmeyer N
BUNDESGESUNDHEITSBLA. 2017;60(2):245-254.

In vitro susceptibility to 19 agents other than β-lactams among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission
Mischnik A, Baumert P, Hamprecht A, Rohde A, Peter S, Feihl S, Knobloch J, Gölz H, Kola A, Obermann B, Querbach C, Willmann M, Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern W
J ANTIMICROB CHEMOTH. 2017;72(5):1359-1363.

Susceptibility to cephalosporin combinations and aztreonam/avibactam among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission
Mischnik A, Baumert P, Hamprecht A, Rohde A, Peter S, Feihl S, Knobloch J, Gölz H, Kola A, Obermann B, Querbach C, Willmann M, Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern W
INT J ANTIMICROB AG. 2017;49(2):239-242.

Actin-Dependent Regulation of Borrelia burgdorferi Phagocytosis by Macrophages
Naj X, Linder S
CURR TOP MICROBIOL. 2017;399:133-154.

The metalloprotease SepA governs processing of accumulation-associated protein and shapes intercellular adhesive surface properties in Staphylococcus epidermidis
Paharik A, Kotasinska M, Both A, Hoang T, Büttner H, Roy P, Fey P, Horswill A, Rohde H
MOL MICROBIOL. 2017;103(5):860-874.

Genetic and biochemical characterization of HMB-1, a novel subclass B1 metallo-β-lactamase found in a Pseudomonas aeruginosa clinical isolate
Pfennigwerth N, Lange F, Belmar Campos C, Hentschke M, Gatermann S, Kaase M
J ANTIMICROB CHEMOTH. 2017;72(4):1068-1073.

High Abundance and Genetic Variability of Atypical Porcine Pestivirus in Pigs from Europe and Asia
Postel A, Meyer D, Cagatay G, Feliziani F, De Mia G, Fischer N, Grundhoff A, Milićević V, Deng M, Chang C, Qiu H, Sun Y, Wendt M, Becher P
EMERG INFECT DIS. 2017;23(12):2104-2107.

Drebrin's Role in the Maintenance of Endothelial Integrity
Rehm K, Linder S
ADV EXP MED BIOL. 2017;1006:347-360.

Actin assembly mechanisms at a glance
Rottner K, Faix J, Bogdan S, Linder S, Kerkhoff E
J CELL SCI. 2017;130(20):3427-3435.

Successful retreatment of a patient with chronic hepatitis C genotype 2k/1b virus with ombitasvir/paritaprevir/ritonavir plus dasabuvir
Todt D, Schlevogt B, Deterding K, Grundhoff A, Manns M, Wedemeyer H, Fischer N, Cornberg M, Steinmann E
J ANTIMICROB CHEMOTH. 2017;72(5):1541-1543.

Oral Human Papillomavirus in Women With High-Grade Cervical Intraepithelial Neoplasia
Woelber L, Breuer J, Meyer T, Vettorazzi E, Prieske K, Bohlmann I, Busch C, Teudt I, Brummer O, Mueller V, Schmalfeldt B, Grimm D
J LOW GENIT TRACT DI. 2017;21(3):177-183.

Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation
Allweiss L, Gass S, Giersch K, Groth A, Kah J, Volz T, Rapp G, Schöbel A, Lohse A, Polywka S, Pischke S, Herker E, Dandri-Petersen M, Lütgehetmann M
J HEPATOL. 2016;64(5):1033-1040.

Pegivirus Infection in Domestic Pigs, Germany
Baechlein C, Grundhoff A, Fischer N, Alawi M, Hoeltig D, Waldmann K, Becher P
EMERG INFECT DIS. 2016;22(7):1312-4.

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells
Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney A, Nolte F, Buck F, Perbandt M, Betzel C, Svergun D, Hentschke M, Aepfelbacher M
PLOS PATHOG. 2016;12(6):e1005660.

Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer
Bierwolf J, Volz T, Lütgehetmann M, Allweiss L, Riecken K, Warlich M, Fehse B, Kalff J, Dandri-Petersen M, Pollok J
TISSUE ENG PT A. 2016;22(9-10):742-53.

First report of Escherichia coli co-producing NDM-1 and OXA-232
Both A, Huang J, Kaase M, Hezel J, Wertheimer D, Fenner I, Günther T, Grundhoff A, Büttner H, Aepfelbacher M, Rohde H, Hentschke M
DIAGN MICR INFEC DIS. 2016;86(4):437-438.

Moderne Diagnostik sexuell übertragbarer Infektionen
Brockmeyer N, Meyer T
HAUTARZT. 2016;67(1):16-22.

Nasal commensal Staphylococcus epidermidis counteracts influenza virus
Chen H, Liu P, Liu Y, Kuo S, Zhang X, Schooley R, Rohde H, Gallo R, Huang C
SCI REP-UK. 2016;6:27870.

Antagonism between Staphylococcus epidermidis and Propionibacterium acnes and its genomic basis
Christensen G, Scholz C, Enghild J, Rohde H, Kilian M, Thürmer A, Brzuszkiewicz E, Lomholt H, Brüggemann H
BMC GENOMICS. 2016;17:152.

Suspected encephalitis with Candida tropicalis and Fusarium detected by unbiased RNA sequencing
Christopeit M, Grundhoff A, Rohde H, Belmar-Campos C, Grzyska U, Fiehler J, Wolschke C, Kröger N, Fischer N
ANN HEMATOL. 2016;95(11):1919-1921.

Efficacy and safety of sofosbuvir/ledipasvir for the treatment of patients with hepatitis C virus re-infection after liver transplantation
Ciesek S, Proske V, Otto B, Pischke S, Costa R, Lütgehetmann M, Polywka S, Klempnauer J, Nashan B, Manns M, von Hahn T, Lohse A, Wedemeyer H, Mix H, Sterneck M
TRANSPL INFECT DIS. 2016;18(3):326-32.

Antibiotic resistance and clonal diversity of invasive Staphylococcus aureus in the rural Ashanti Region, Ghana
Dekker D, Wolters M, Mertens E, Boahen K, Krumkamp R, Eibach D, Schwarz N, Adu-Sarkodie Y, Rohde H, Christner M, Marks F, Sarpong N, May J
BMC INFECT DIS. 2016;16(1):720.

Extended spectrum beta-lactamase producing Enterobacteriaceae causing bloodstream infections in rural Ghana, 2007-2012
Eibach D, Campos C, Krumkamp R, Al-Emran H, Dekker D, Boahen K, Kreuels B, Adu-Sarkodie Y, Aepfelbacher M, Park S, Panzner U, Marks F, May J
INT J MED MICROBIOL. 2016;306(4):249-54.

Metalloproteinase MT1-MMP islets act as memory devices for podosome reemergence
El Azzouzi K, Wiesner C, Linder S
J CELL BIOL. 2016;213(1):109-25.

Investigation of Viral and Host Chromatin by ChIP-PCR or ChIP-Seq Analysis
Günther T, Theiss J, Fischer N, Grundhoff A
Curr Protoc Microbiol. 2016;40:1E.10.1-1E.10.21.

Biofilm Morphotypes and Population Structure among Staphylococcus epidermidis from Commensal and Clinical Samples
Harris L, Murray S, Pascoe B, Bray J, Meric G, Magerios L, Wilkinson T, Jeeves R, Rohde H, Schwarz S, de Lencastre H, Miragaia M, Rolo J, Bowden R, Jolley K, Maiden M, Mack D, Sheppard S
PLOS ONE. 2016;11(3):e0151240.

Persisting hepatitis E virus infection leading to liver cirrhosis despite recovery of the immune system in an HIV-infected patient
Ingiliz P, Mayr C, Obermeier M, Herbst H, Polywka S, Pischke S
CLIN RES HEPATOL GAS. 2016;40(3):e23-5.

Tedizolid susceptibility in linezolid- and vancomycin-resistant Enterococcus faecium isolates
Klupp E, Both A, Belmar Campos C, Büttner H, König C, Christopeit M, Christner M, Aepfelbacher M, Rohde H
EUR J CLIN MICROBIOL. 2016;35(12):1957-1961.

Attenuated viral hepatitis in Trem1-/- mice is associated with reduced inflammatory activity of neutrophils
Kozik J, Trautmann T, Carambia A, Preti M, Lütgehetmann M, Krech T, Wiegard C, Heeren J, Herkel J
SCI REP-UK. 2016;6:28556.

Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney
Krebs C, Paust H, Krohn S, Koyro T, Brix S, Riedel J, Bartsch P, Wiech T, Meyer-Schwesinger C, Huang J, Fischer N, Busch C, Mittrücker H, Steinhoff U, Stockinger B, Perez L, Wenzel U, Janneck M, Steinmetz O, Gagliani N, Stahl R, Huber S, Turner J, Panzer U
IMMUNITY. 2016;45(5):1078-1092.

Feel the force: Podosomes in mechanosensing
Linder S, Wiesner C
EXP CELL RES. 2016;343(1):67-72.

Kinetics of HIV-1 latency reversal quantified on the single cell level using a novel flow-based technique
Martrus G, Niehrs A, Cornelis R, Rechtien A, García-Beltran W, Lütgehetmann M, Hoffmann C, Altfeld M
J VIROL. 2016;90(20):9018-9028.

Diagnostic Procedures to Detect Chlamydia trachomatis Infections
Meyer T
MICROORGANISMS. 2016;4(3):E25.

Performance evaluation of the PelvoCheck CT/NG test kit for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae
Meyer T, Klos C, Kofler R, Kilic A, Hänel K
BMJ OPEN. 2016;6(1):e009894.

Susceptibility to penicillin derivatives among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission
Mischnik A, Baumert P, Hamprecht A, Rohde A, Peter S, Feihl S, Knobloch J, Gölz H, Kola A, Obermann B, Querbach C, Willmann M, Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern W
DIAGN MICR INFEC DIS. 2016;87(1):71-73.

Variability in long-term hepatitis B virus dynamics under antiviral therapy
Murray J, Stancevic O, Lütgehetmann M, Wursthorn K, Petersen J, Dandri-Petersen M
J THEOR BIOL. 2016;391:74-80.

Replication of merkel cell polyomavirus induces reorganization of promyelocytic leukemia nuclear bodies
Neumann F, Czech-Sioli M, Dobner T, Grundhoff A, Schreiner S, Fischer N
J GEN VIROL. 2016;97(11):2926-2938.

The Technical and Biological Reproducibility of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) Based Typing: Employment of Bioinformatics in a Multicenter Study
Oberle M, Wohlwend N, Jonas D, Maurer F, Jost G, Tschudin-Sutter S, Vranckx K, Egli A
PLOS ONE. 2016;11(10):e0164260.

The formins FHOD1 and INF2 regulate inter- and intra-structural contractility of podosomes
Panzer L, Trübe L, Klose M, Joosten B, Slotman J, Cambi A, Linder S
J CELL SCI. 2016;129(2):298-313.

Blood-borne Hepatitis E Virus Transmission: A Relevant Risk for Immunosuppressed Patients
Pischke S, Hiller J, Lütgehetmann M, Polywka S, Rybczynski M, Ayuketang F, Lohse A
CLIN INFECT DIS. 2016;63(4):569-570.

Course of hepatitis C virus (HCV) RNA and HCV core antigen testing are predictors for reaching sustained virologic response in liver transplant recipients undergoing sofosbuvir treatment in a real-life setting
Pischke S, Polywka S, Proske V, Lang M, Jordan S, Nashan B, Lohse A, Sterneck M
TRANSPL INFECT DIS. 2016;18:141-145.

Frequent presence of hepaci and pegiviruses in commercial equine serum pools
Postel A, Cavalleri J, Pfaender S, Walter S, Steinmann E, Fischer N, Feige K, Haas L, Becher P
VET MICROBIOL. 2016;182:8-14.

Presence of atypical porcine pestivirus (APPV) genomes in newborn piglets correlates with congenital tremor
Postel A, Hansmann F, Baechlein C, Fischer N, Alawi M, Grundhoff A, Derking S, Tenhündfeld J, Pfankuche V, Herder V, Baumgärtner W, Wendt M, Becher P
SCI REP-UK. 2016;6:27735.

Staphylococcus aureus recruits Cdc42GAP through recycling endosomes and the exocyst to invade human endothelial cells
Rauch L, Hennings K, Trasak C, Röder A, Schröder B, Nolte F, Rivera-Molina F, Toomre D, Aepfelbacher M
J CELL SCI. 2016;129(15):2937-49.

Severe Community-Acquired Bloodstream Infection with Acinetobacter ursingii in Person who Injects Drugs
Salzer H, Rolling T, Schmiedel S, Klupp E, Lange C, Seifert H
EMERG INFECT DIS. 2016;22(1):134-7.

Versatility of Biofilm Matrix Molecules in Staphylococcus epidermidis Clinical Isolates and Importance of Polysaccharide Intercellular Adhesin Expression during High Shear Stress
Schaeffer C, Hoang T, Sudbeck C, Alawi M, Tolo I, Robinson D, Horswill A, Rohde H, Fey P
MSPHERE. 2016;1(5):e00165-16..

Breadth of the HCV-specific CD4+ T-cell response in spontaneous resolvers is independent of the IL-28 haplotype
Scheurich C, Schulze Zur Wiesch J, Kim A, Lewis-Ximenez L, Meyer T, Polywka S, Chung R, Lauer G
J VIRAL HEPATITIS. 2016;23(10):831-2.

Changes in HIV-1 Capsid Stability Induced by Common Cytotoxic-T-Lymphocyte-Driven Viral Sequence Mutations
Schommers P, Martrus G, Matschl U, Sirignano M, Lütgehetmann M, Richert L, Hope T, Fätkenheuer G, Altfeld M
J VIROL. 2016;90(16):7579-86.

Does galactomannan testing increase diagnostic accuracy for IPA in the ICU? - A prospective observational study
Schroeder M, Simon M, Katchanov J, Wijaya C, Rohde H, Christner M, Laqmani A, Wichmann D, Fuhrmann V, Kluge S
CRIT CARE. 2016;20(1):139.

Dynamic in vivo mutations within the ica operon during persistence of Staphylococcus aureus in the airways of cystic fibrosis patients
Schwartbeck B, Birtel J, Treffon J, Langhanki L, Mellmann A, Kale D, Kahl J, Hirschhausen N, Neumann C, Lee J, Götz F, Rohde H, Henke H, Küster P, Peters G, Kahl B
PLOS PATHOG. 2016;12(11):e1006024.

Tropheryma whipplei in children with diarrhoea in rural Ghana
Vinnemeier C, Klupp E, Krumkamp R, Rolling T, Fischer N, Owusu-Dabo E, Addo M, Adu-Sarkodie Y, Käsmaier J, Aepfelbacher M, Cramer J, May J, Tannich E
CLIN MICROBIOL INFEC. 2016;22(1):65.e1 - 65.e3.

Sub-inhibitory tigecycline concentrations induce extracellular matrix binding protein Embp dependent Staphylococcus epidermidis biofilm formation and immune evasion
Weiser J, Henke H, Hector N, Both A, Christner M, Büttner H, Kaplan J, Rohde H
INT J MED MICROBIOL. 2016;306(6):471-478.

Genetic engineering of untransformable coagulase-negative staphylococcal pathogens
Winstel V, Kühner P, Rohde H, Peschel A
NAT PROTOC. 2016;11(5):949-59.

Effects of polysaccharide intercellular adhesin (PIA) in an ex vivo model of whole blood killing and in prosthetic joint infection (PJI): A role for C5a
Al-Ishaq R, Armstrong J, Gregory M, O'Hara M, Phiri K, Harris L, Rohde H, Siemssen N, Frommelt L, Mack D, Wilkinson T
INT J MED MICROBIOL. 2015;305(8):948-56.

Structural basis of Staphylococcus epidermidis biofilm formation: mechanisms and molecular interactions
Büttner H, Mack D, Rohde H
FRONT CELL INFECT MI. 2015;5:14.

Highly divergent hepaciviruses from African cattle
Corman V, Grundhoff A, Baechlein C, Fischer N, Gmyl A, Wollny R, Dei D, Ritz D, Binger T, Adankwah E, Marfo K, Annison L, Annan A, Adu-Sarkodie Y, Oppong S, Becher P, Drosten C, Drexler J
J VIROL. 2015;89(11):5876-82.

Experimental Models: Cell Culture and Animal Models
Dandri-Petersen M, Volz T, Lütgehetmann M
2015. Hepatitis B Virus in Human Diseases . Liaw Y, Zoulim F (Hrsg.). 1. Aufl. Springer International Publishing, 35-62.

An 18 kDa Scaffold Protein Is Critical for Staphylococcus epidermidis Biofilm Formation
Decker R, Burdelski C, Zobiak M, Büttner H, Franke G, Christner M, Saß K, Zobiak B, Henke H, Horswill A, Bischoff M, Bur S, Hartmann T, Schaeffer C, Fey P, Rohde H
PLOS PATHOG. 2015;11(3):e1004735.

Soluble plasma VE-cadherin concentrations are elevated in patients with STEC infection and haemolytic uraemic Syndrome: a case-control study
Doulgere J, Otto B, Nassour M, Wolters-Eisfeld G, Rohde H, Magnus T, Wagener C, Streichert T
BMJ OPEN. 2015;5(3):e005659.

Isolation, identification and functional profile of excretory-secretory peptides from Onchocerca ochengi
Eberle R, Brattig N, Trusch M, Schlüter H, Achukwi M, Eisenbarth A, Renz A, Liebau E, Perbandt M, Betzel C
ACTA TROP. 2015;142:156-66.

Identification of a Novel Hepacivirus in Domestic Cattle from Germany
Fischer N, Baechlein C, Grundhoff A, Alawi M, Indenbirken D, Postel A, Baron A, Offinger J, Becker K, Beineke A, Rehage J, Becher P
J VIROL. 2015;89(14):7007-15.

Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples
Fischer N, Indenbirken D, Meyer T, Lütgehetmann M, Lellek H, Spohn M, Aepfelbacher M, Alawi M, Grundhoff A
J CLIN MICROBIOL. 2015;53(7):2238-50.

Relevance of chronic hepatitis E in liver transplant recipients: a real-life setting
Galante A, Pischke S, Polywka S, Lütgehetmann M, Suneetha P, Gisa A, Hiller J, Dienes H, Nashan B, Lohse A, Sterneck M
TRANSPL INFECT DIS. 2015;17(4):617-22.

Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection
Giersch K, Allweiss L, Volz T, Helbig M, Bierwolf J, Lohse A, Pollok J, Petersen J, Dandri-Petersen M, Lütgehetmann M
J HEPATOL. 2015;63(2):346-53.

Merkel cell polyomavirus, a highly prevalent virus with tumorigenic potential
Grundhoff A, Fischer N
CURR OPIN VIROL. 2015;14:129-137.

Comparison of autochthonous and imported cases of hepatitis A or hepatitis E
Hartl J, Kreuels B, Polywka S, Addo M, Lütgehetmann M, Dandri-Petersen M, Dammermann W, Sterneck M, Lohse A, Pischke S
Z GASTROENTEROL. 2015;53(7):639-643.

Spezifische Symptomkombination der chronischen Quecksilberintoxikation: Arterielle Hypertension, Entwicklungsregression und Automutilation
Hermann K, Varwig-Janßen D, Budnik L, Nordholt G, Reinshagen K, Oh J, Santer R, Mühlhausen C
MONATSSCHR KINDERH. 2015;163(6):570-574.

GTP-specific fab fragment-based GTPase activity assay
Kopra K, Rozwandowicz-Jansen A, Syrjänpää M, Blaževitš O, Ligabue A, Veltel S, Lamminmäki U, Abankwa D, Härmä H
ANAL CHEM. 2015;87(6):3527-34.

Emergence of daptomycin non-susceptibility in colonizing vancomycin-resistant Enterococcus faecium isolates during daptomycin therapy
Lellek H, Franke G, Ruckert C, Wolters M, Wolschke C, Christner M, Büttner H, Alawi M, Kröger N, Rohde H
INT J MED MICROBIOL. 2015;305(8):902-909.

Investigations on CXCL13 in anti-N-methyl-D-aspartate receptor encephalitis: a potential biomarker of treatment response
Leypoldt F, Höftberger R, Titulaer M, Armangue T, Gresa-Arribas N, Jahn H, Rostásy K, Schlumberger W, Meyer T, Wandinger K, Rosenfeld M, Graus F, Dalmau J
JAMA NEUROL. 2015;72(2):180-6.

MT1-MMP: Endosomal delivery drives breast cancer metastasis
Linder S
J CELL BIOL. 2015;211(2):215-7.

RABGTPases in MT1-MMP trafficking and cell invasion:Physiology versus pathology
Linder S, Scita G
Small GTPases. 2015;6(3):145-52.

Tools of the trade: podosomes as multipurpose organelles of monocytic cells
Linder S, Wiesner C
CELL MOL LIFE SCI. 2015;72(1):121-35.

Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion
Lin Y, Bhuwania R, Gromova K, Failla A, Lange T, Riecken K, Linder S, Kneussel M, Izbicki J, Windhorst S
ONCOTARGET. 2015;6(21):18577-89.

Definition of Chronic Hepatitis E after Liver Transplantation Conforms to Convention
Meisner S, Polywka S, Memmler M, Nashan B, Lohse A, Sterneck M, Pischke S
AM J TRANSPLANT. 2015;15(11):3011-3012.

Atovaquone for Prophylaxis of Toxoplasmosis after Allogeneic Hematopoietic Stem Cell Transplantation.
Mendorf A, Klyuchnikov E, Langebrake C, Rohde H, Ayuketang F, Regier M, Christopeit M, Zabelina T, Bacher A, Stübig T, Wolschke C, Bacher U, Kroger N
ACTA HAEMATOL-BASEL. 2015;134(3):146-154.

Diagnostik sexuell übertragbarer Infektionen.
Meyer T, Püschel K, Seifert D
RECHTSMEDIZIN. 2015;25(2):107-119.

ER-Coordinated Activities of Rab22a and Rab5a Drive Phagosomal Compaction and Intracellular Processing of Borrelia burgdorferi by Macrophages
Naj X, Linder S
CELL REP. 2015;12(11):1816-1830.

In Vitro Replication Assay for Merkel Cell Polyomavirus (MCPyV)
Neumann F, Czech-Sioli M, Grundhoff A, Fischer N
Curr Protoc Microbiol. 2015;38:14F.2.1-14F.2.19.

Hepatitis E Virus
Pauli G, Aepfelbacher M, Bauerfeind U, Blümel J, Burger R, Gärtner B, Gröner A, Gürtler L, Heiden M, Hildebrandt M, Jansen B, Offergeld R, Schlenkrich U, Schottstedt V, Seitz R, Strobel J, Willkommen H, Baylis S
TRANSFUS MED HEMOTH. 2015;42(4):247-65.

High resolution structures of Plasmodium falciparum GST complexes provide novel insights into the dimer-tetramer transition and a novel ligand-binding site
Perbandt M, Eberle R, Fischer-Riepe L, Cang H, Liebau E, Betzel C
J STRUCT BIOL. 2015;191(3):365-75.

Association of hepatitis E virus and essential cryoglobulinemia?
Pischke S, Polywka S, Haag F, Iking-Konert C, Sterneck M, Lütgehetmann M, Dammermann W, Lüth S, Schirmer J
J CLIN VIROL. 2015;67:23-24.

Close relationship of ruminant pestiviruses and classical Swine Fever virus
Postel A, Schmeiser S, Oguzoglu T, Indenbirken D, Alawi M, Fischer N, Grundhoff A, Becher P
EMERG INFECT DIS. 2015;21(4):668-72.

Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
Salzer H, Rolling T, Klupp E, Schmiedel S
Med Mycol Case Rep. 2015;8:17-20.

Accumulation-associated protein enhances Staphylococcus epidermidis biofilm formation under dynamic conditions and is required for infection in a rat catheter model
Schaeffer C, Woods K, Longo G, Kiedrowski M, Paharik A, Büttner H, Christner M, Boissy R, Horswill A, Rohde H, Fey P
INFECT IMMUN. 2015;83(1):214-26.

A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence
Theiss J, Günther T, Alawi M, Neumann F, Tessmer U, Fischer N, Grundhoff A
PLOS PATHOG. 2015;11(7):e1004974.

Selection of Nanobodies that Block the Enzymatic and Cytotoxic Activities of the Binary Clostridium Difficile Toxin CDT
Unger M, Eichhoff A, Schumacher L, Strysio M, Menzel S, Schwan C, Alzogaray V, Zylberman V, Seman M, Brandner J, Rohde H, Zhu K, Haag F, Mittrücker H, Goldbaum F, Aktories K, Nolte F
SCI REP-UK. 2015;5:7850.

Transfer of plasmid DNA to clinical coagulase-negative staphylococcal pathogens using a unique bacteriophage
Winstel V, Kühner P, Krismer B, Peschel A, Rohde H
APPL ENVIRON MICROB. 2015;81:2481–2488..

Analysis of Yersinia enterocolitica Effector Translocation into Host Cells Using Beta-lactamase Effector Fusions.
Wolters M, Zobiak B, Nauth T, Aepfelbacher M
JOVE-J VIS EXP. 2015;(104):.

Preliminary crystallographic analysis of a cruciferin protein from seeds of Moringa oleifera
Akrem A, Yousef N, Begum A, Negm A, Meyer A, Perbandt M, Buck F, Betzel C
PROTEIN J. 2014;33(3):253-7.

Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration
Allweiss L, Volz T, Lütgehetmann M, Giersch K, Bornscheuer T, Lohse A, Petersen J, Ma H, Klumpp K, Fletcher S, Dandri M
J HEPATOL. 2014;60(3):500-7.

Complete Genome Sequence of Bovine Pestivirus Strain PG-2, a Second Member of the Tentative Pestivirus Species Giraffe
Becher P, Fischer N, Grundhoff A, Stalder H, Schweizer M, Postel A
Genome Announc. 2014;2(3):.

Prevalence and genotypes of extended spectrum beta-lactamases in Enterobacteriaceae isolated from human stool and chicken meat in Hamburg, Germany
Belmar Campos C, Fenner I, Wiese N, Lensing C, Christner M, Rohde H, Aepfelbacher M, Fenner T, Hentschke M
INT J MED MICROBIOL. 2014;304(5-6):678-684.

Microtubule acetylation regulates dynamics of KIF1C-powered vesicles and contact of microtubule plus ends with podosomes
Bhuwania R, Castro-Castro A, Linder S
EUR J CELL BIOL. 2014;93(10-12):424-37.

High-affinity Rb Binding, p53 Inhibition, Subcellular Localization, and Transformation by Wild-Type or Tumor-Derived Shortened Merkel Cell Polyomavirus Large T Antigens
Borchert S, Czech-Sioli M, Neumann F, Schmidt C, Wimmer P, Dobner T, Grundhoff A, Fischer N
J VIROL. 2014;88(6):3144-60.

Radiography-based score indicative for the pathogenicity of bacteria in odontogenic infections
Cachovan G, Blessmann M, Schön G, Rother U, Heiland M, Stürenburg E, Platzer U, Sobottka I
ACTA ODONTOL SCAND. 2014;72(7):530-536.

Rapid MALDI-TOF mass spectrometry strain typing during a large outbreak of Shiga-Toxigenic Escherichia coli
Christner M, Trusch M, Rohde H, Kwiatkowski M, Schlüter H, Wolters M, Aepfelbacher M, Hentschke M
PLOS ONE. 2014;9(7):e101924.

Mouse models of hepatitis B and delta virus infection
Dandri M, Lütgehetmann M
J IMMUNOL METHODS. 2014;410:39-49.

Merkel Cell Polyomavirus
Fischer N, Adam G
2014. Cancers in People with HIV and AIDS. Yarchoan R (Hrsg.). 1. Aufl. Springer, 113-122.

Nachweis von Bakterien, Pilzen und Viren im Hochdurchsatz
Fischer N, Grundhoff A
BIOspektrum. 2014;20(5):524-527.

Rapid Metagenomic Diagnostics for Suspected Outbreak of Severe Pneumonia
Fischer N, Rohde H, Indenbirken D, Günther T, Reumann K, Lütgehetmann M, Meyer T, Kluge S, Aepfelbacher M, Alawi M, Grundhoff A
EMERG INFECT DIS. 2014;20(6):1072-5.

Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection
Giersch K, Helbig M, Volz T, Allweiss L, Mancke L, Lohse A, Polywka S, Pollok J, Petersen J, Taylor J, Dandri M, Lütgehetmann M
J HEPATOL. 2014;60(3):538-44.

Is rapid hepatitis C virus testing from corpses a screening option for index persons who have died after mass-casualty incidents in high-prevalence settings in the field?
Hagen R, Wulff B, Loderstaedt U, Fengler I, Frickmann H, Schwarz N, Polywka S
J ROY ARMY MED CORPS. 2014;160(3):226-31.

Daam1 is a regulator of filopodia formation and phagocytic uptake of Borrelia burgdorferi by primary human macrophages
Hoffmann A, Naj X, Linder S
FASEB J. 2014;28(7):3075-3089.

RNA folding space analysis using structure abstraction
Huang J
2014.

Whole-genome sequencing for risk assessment of long-term Shiga toxin-producing Escherichia coli
Knobloch J, Niemann S, Kohl T, Lindner U, Nitschke M, Sayk F, Solbach W
EMERG INFECT DIS. 2014;20(4):732-3.

A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction
Kopra K, Ligabue A, Wang Q, Syrjänpää M, Blaževitš O, Veltel S, van Adrichem A, Hänninen P, Abankwa D, Härmä H
ANAL BIOANAL CHEM. 2014;406(17):4147-56.

Sample displacement batch chromatography of proteins
Kotasinska M, Richter V, Kwiatkowski M, Schlüter H
Methods Mol Biol. 2014;1129:325-38.

Micafungin as antifungal prophylaxis in recipients of allogeneic hematopoietic stem cell Transplantation: results of different dosage levels in clinical practice
Langebrake C, Rohde H, Lellek H, Wolschke C, Kröger N
CLIN TRANSPLANT. 2014;28(3):286-91.

Merkel cell polyomavirus detection in Merkel cell cancer tumors in Northern Germany using PCR and protein expression
Leitz M, Stieler K, Grundhoff A, Moll I, Brandner J, Fischer N
J MED VIROL. 2014;86 (10):1813-1819.

Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay
Meyer T, Franke G, Polywka S, Lütgehetmann M, Gbadamosi J, Magnus T, Aepfelbacher M
J CLIN MICROBIOL. 2014;52(5):1751-3.

Complete Genome Sequence of Pronghorn Virus, a Pestivirus.
Neill J, Ridpath J, Fischer N, Grundhoff A, Postel A, Becher P
Genome Announc. 2014;2(3):e00575-14.

Cell death triggered by Yersinia enterocolitica identifies processing of the proinflammatory signal adapter MyD88 as a general event in the execution of apoptosis
Novikova L, Czymmeck N, Deuretzbacher A, Buck F, Richter K, Weber A, Aepfelbacher M, Ruckdeschel K
J IMMUNOL. 2014;192(3):1209-19.

Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism
Oehler N, Volz T, Bhadra O, Kah J, Allweiss L, Giersch K, Bierwolf J, Riecken K, Pollok J, Lohse A, Fehse B, Petersen J, Urban S, Lütgehetmann M, Heeren J, Dandri M
HEPATOLOGY. 2014.

Staphylococcus epidermidis agr quorum-sensing system: signal identification, cross talk, and importance in colonization
Olson M, Todd D, Schaeffer C, Paharik A, Van Dyke M, Büttner H, Dunman P, Rohde H, Cech N, Fey P, Horswill A
J BACTERIOL. 2014;196(19):3482-93.

Protective mechanisms of helminths against reactive oxygen species are highly promising drug targets.
Perbandt M, Ndonka D, Liebau E
CURR MED CHEM. 2014;19(15):1794-1808.

A role for exocyst in maturation and bactericidal function of staphylococci-containing endothelial cell phagosomes
Rauch L, Hennings K, Aepfelbacher M
TRAFFIC. 2014;15(10):1083-98.

New foe treated with old guns - supportive role of steroids in the treatment of acute severe hepatitis E
Sebode M, Pischke S, Lütgehetmann M, Polywka S, Quaas A, Lohse A, Wege H
BMC GASTROENTEROL. 2014;14(191):.

Sinecatechins (Polyphenon E) ointment for treatment of external genital warts and possible future indications
Stockfleth E, Meyer T
EXPERT OPIN BIOL TH. 2014;14(7):1033-43.

A multicentre cohort study on colonization and infection with ESBL-producing Enterobacteriaceae in high-risk patients with haematological malignancies
Vehreschild M, Hamprecht A, Peterson L, Schubert S, Häntschel M, Peter S, Schafhausen P, Rohde H, Lilienfeld-Toal M, Bekeredjian-Ding I, Libam J, Hellmich M, Vehreschild J, Cornely O, Seifert H
J ANTIMICROB CHEMOTH. 2014;69(12):3387-92.

Surveillanceberichte zu Erregern und Antibiotikaresistenzen - eine Empfehlung zur Standardisierung
Warnke P, Aepfelbacher M, Fickenscher H, Solbach W, Steinmetz I, Podbielski A
DEUT MED WOCHENSCHR. 2014;139(25-26):1377-82.

Podosomes in space: Macrophage migration and matrix degradation in 2D and 3D settings
Wiesner C, Le-Cabec V, El Azzouzi K, Maridonneau-Parini I, Linder S
CELL ADHES MIGR. 2014;8(3):179-191.

cyp51A-Based mechanisms of Aspergillus fumigatus azole drug resistance present in clinical samples from Germany
Bader O, Weig M, Reichard U, Lugert R, Kuhns M, Christner M, Held J, Peter S, Schumacher U, Buchheidt D, Tintelnot K, Groß U
ANTIMICROB AGENTS CH. 2013;57(8):3513-7.

Staphylococcus aureus thiaminase II: oligomerization warrants proteolytic protection against serine proteases.
Begum A, Drebes J, Kikhney A, Mueller I, Perbandt M, Svergun D, Wrenger C, Betzel C
ACTA CRYSTALLOGR D. 2013;(69):2320-2329.

Reisediarrhoe
Burchard G, Hentschke M, Weinke T, Nothdurft H
DEUT MED WOCHENSCHR. 2013;138(33):1673-83; quiz 1684-6.

Podosome reformation in macrophages: assays and analysis
Cervero P, Panzer L, Linder S
Methods Mol Biol. 2013;1046:97-121.

Renal intercalated cells are rather energized by a proton than a sodium pump
Chambrey R, Kurth I, Peti-Peterdi J, Houillier P, Purkerson J, Leviel F, Hentschke M, Zdebik A, Schwartz G, Hübner C, Eladari D
P NATL ACAD SCI USA. 2013;110(19):7928-33.

Experimental models and therapeutic approaches for HBV
Dandri M, Lütgehetmann M, Petersen J
SEMIN IMMUNOPATHOL. 2013;35(1):7-21.

Rapid discrimination of Haemophilus influenzae, H. parainfluenzae, and H. haemolyticus by fluorescence in situ hybridization (FISH) and two matrix-assisted laser-desorption-ionization time-of-flight mass spectrometry (MALDI-TOF-MS) platforms
Frickmann H, Christner M, Donat M, Berger A, Essig A, Podbielski A, Hagen R, Poppert S
PLOS ONE. 2013;8(4):e63222.

From IEDs to AIDS? Detection of HIV in human corpses by rapid screening tests after suspected intentional transmission in terrorist attacks
Frickmann H, Wulff B, Loderstædt U, Hagen R, Sturm D, Polywka S
J ROY ARMY MED CORPS. 2013;159(4):278-82.

Analysis of the matrix-assisted laser desorption ionization-time of flight mass spectrum of Staphylococcus aureus identifies mutations that allow differentiation of the main clonal lineages
Josten M, Reif M, Szekat C, Al-Sabti N, Roemer T, Sparbier K, Kostrzewa M, Rohde H, Sahl H, Bierbaum G
J CLIN MICROBIOL. 2013;51(6):1809-17.

Increased T helper type 17 response to pathogen stimulation in patients with primary sclerosing cholangitis
Katt J, Schwinge D, Schoknecht T, Quaas A, Sobottka I, Burandt E, Becker C, Neurath M, Lohse A, Herkel J, Schramm C
HEPATOLOGY. 2013;58(3):1084-93.

Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: case report
Leypoldt F, Titulaer M, Aguilar E, Walther J, Bönstrup M, Havemeister S, Teegen B, Lütgehetmann M, Rosenkranz M, Magnus T, Dalmau J
NEUROLOGY. 2013;81(18):1637-9.

Risk factors for donor cornea contamination: retrospective analysis of 4546 procured corneas in a single eye bank.
Linke S, Fricke O, Eddy M, Bednarz J, Druchkiv V, Kaulfers P, Wulff B, Püschel K, Richard G, Hellwinkel O
CORNEA. 2013;32(2):141-148.

A culture-independent sequence-based metagenomics approach to the investigation of an outbreak of Shiga-toxigenic Escherichia coli O104:H4
Loman N, Constantinidou C, Christner M, Rohde H, Chan J, Quick J, Weir J, Quince C, Smith G, Betley J, Aepfelbacher M, Pallen M
JAMA-J AM MED ASSOC. 2013;309(14):1502-10.

Resiquimod, a topical drug for viral skin lesions and skin cancer.
Meyer T, Surber C, French L, Stockfleth E
EXPERT OPIN INV DRUG. 2013;22(1):149-159.

The formins FMNL1 and mDia1 regulate coiling phagocytosis of Borrelia burgdorferi by primary human macrophages
Naj X, Hoffmann A, Himmel M, Linder S
INFECT IMMUN. 2013;81(5):1683-95.

Drebrin preserves endothelial integrity by stabilizing nectin at adherens junctions
Rehm K, Panzer L, van Vliet V, Genot E, Linder S
J CELL SCI. 2013;126(Pt 16):3756-69.

Antagonistic effects of probiotic Escherichia coli Nissle 1917 on EHEC strains of serotype O104:H4 and O157:H7
Rund S, Rohde H, Sonnenborn U, Oelschlaeger T
INT J MED MICROBIOL. 2013;303(1):1-8.

Viral hepatitis in alcohol-dependent inpatients: prevalence, risk factors, and treatment uptake
Schmidt C, Schön D, Schulte B, Lüth S, Polywka S, Reimer J
J ADDICT MED. 2013;7(6):417-21.

Aspergillus galactomannan antigen for diagnosis and treatment monitoring in cerebral aspergillosis
Soeffker G, Wichmann D, Loderstädt U, Sobottka I, Deuse T, Kluge S
PROG TRANSPLANT. 2013;23(1):71-4.

Utilization of replication-competent XMRV reporter-viruses reveals severe viral restriction in primary human cells
Stürzel C, Palesch D, Khalid M, Wissing S, Fischer N, Münch J
PLOS ONE. 2013;8(9):e74427.

3C protease of enterovirus 68: structure-based design of Michael acceptor inhibitors and their broad-spectrum antiviral effects against picornaviruses.
Tan J, Georg S, Kursov Y, Perbandt M, Anemueller S, Mesters J, Norder H, Coutardt B, Lacroix C, Leyssen P, Neyts J, Hilgenfeld R
J VIROL. 2013;87(8):4339-4351.

The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus
Volz T, Allweiss L, Ben MBarek M, Warlich M, Lohse A, Pollok J, Alexandrov A, Urban S, Petersen J, Lütgehetmann M, Dandri M
J HEPATOL. 2013;58(5):861-7.

Duration of fecal shedding of Shiga toxin-producing Escherichia coli O104:H4 in patients infected during the 2011 outbreak in Germany: a multicenter study
Vonberg R, Höhle M, Aepfelbacher M, Bange F, Belmar Campos C, Claussen K, Christner M, Cramer J, Haller H, Hornef M, Fickenscher H, Zimmermann-Fraedrich K, Knobloch J, Kühbacher T, Manns M, Nitschke M, Peters G, Pulz M, Rohde H, Roseland R, Sayk F, Schaumburg F, Schöcklmann H, Schubert S, Solbach W, Karch H, Suerbaum S
CLIN INFECT DIS. 2013;56(8):1132-40.

A novel optineurin truncating mutation and three glaucoma-associated missense variants in patients with familial amyotrophic lateral sclerosis in Germany
Weishaupt J, Waibel S, Birve A, Volk A, Mayer B, Meyer T, Ludolph A, Andersen P
NEUROBIOL AGING. 2013;34(5):1516.e9-15.

A specific subset of RabGTPases controls cell surface exposure of MT1-MMP, extracellular matrix degradation and three-dimensional invasion of macrophages
Wiesner C, El Azzouzi K, Linder S
J CELL SCI. 2013;126(Pt 13):2820-33.

Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein
Wolters M, Boyle C, Lardong K, Trülzsch K, Steffen A, Rottner K, Ruckdeschel K, Aepfelbacher M
J BIOL CHEM. 2013;288(32):23543-53.

CRN2 enhances the invasiveness of glioblastoma cells
Ziemann A, Hess S, Bhuwania R, Linder S, Kloppenburg P, Noegel A, Clemen C
NEURO-ONCOLOGY. 2013;15(5):548-61.

Functional characterization and immune recognition of the extracellular superoxide dismutase from the human pathogenic parasite Onchocerca volvulus (OvEC-SOD).
Ajonina-Ekoti I, Ndjonka D, Tanyi M, Wilbertz M, Younis A, Boursou D, Kurosinski M, Eberle R, Lüersen K, Perbandt M, Breloer M, Brattig N, Liebau E
ACTA TROP. 2012;124(1):15-26.

Supervillin couples myosin-dependent contractility to podosomes and enables their turnover.
Bhuwania R, Cornfine S, Fang Z, Krüger M, Luna E, Linder S
J CELL SCI. 2012;125(Pt 9):2300-2314.

Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds.
Bierwolf J, Lütgehetmann M, Deichmann S, Erbes J, Volz T, Dandri-Petersen M, Cohen S, Nashan B, Pollok J
TISSUE ENG PT A. 2012;18(13-14):1443-1453.

Proteomic analysis of podosome fractions from macrophages reveals similarities to spreading initiation centres.
Cervero P, Himmel M, Krüger M, Linder S
EUR J CELL BIOL. 2012;91(11-12):908-922.

sarA negatively regulates Staphylococcus epidermidis biofilm formation by modulating expression of 1 MDa extracellular matrix binding protein and autolysis-dependent release of eDNA.
Christner M, Heinze C, Busch M, Franke G, Hentschke M, Sara B, Büttner H, Kotasinska M, Wischnewski V, Kroll G, Buck F, Molin S, Otto M, Rohde H
MOL MICROBIOL. 2012;86(2):394-410.

Despite triple vaccination.
Frickmann H, Scherpe S, Schweiger B, Wählisch S, Reuter K, Bronnert J
J CLIN VIROL. 2012;54(4):291-294.

Structure of the recombinant BPTI/Kunitz-type inhibitor rShPI-1A from the marine invertebrate Stichodactyla helianthus.
García-Fernández R, Pons T, Meyer A, Perbandt M, González-González Y, Gil D, de Los Angeles Chávez M, Betzel C, Redecke L
ACTA CRYSTALLOGR F. 2012;68(Pt 11):1289-1293.

Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor.
García-Fernández R, Pons T, Perbandt M, Valiente P, Talavera A, González-González Y, Rehders D, Chávez M, Betzel C, Redecke L
J STRUCT BIOL. 2012;180(2):271-279.

Reducing the search space in RNA helix based folding. European Conference on Computational Biology
Huang J, Voß B
2012. European Conference on Computational Biology (ECCB) 2012. .

In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer.
Lee D, Jaydip D, Gaughan C, Steffen I, Tang N, Luk K, Qiu X, Urisman A, Fischer N, Molinaro R, Broz M, Schochetman G, Klein E, Ganem D, Derisi J, Simmons G, Hackett J, Silverman R, Chiu C
PLOS ONE. 2012;7(9):44954.

Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.
Lütgehetmann M, Mancke L, Volz T, Helbig M, Allweiss L, Bornscheuer T, Pollok J, Lohse A, Petersen J, Urban S, Dandri-Petersen M
HEPATOLOGY. 2012;55(3):685-694.

Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome:case-control study
Menne J, Nitschke M, Stingele R, Abu-Tair M, Beneke J, Bramstedt J, Bremer J, Brunkhorst R, Busch V, Dengler R, Deuschl G, Fellermann K, Fickenscher H, Gerigk C, Goettsche A, Greeve J, Hafer C, Hagenmüller F, Haller H, Herget-Rosenthal S, Hertenstein B, Hofmann C, Lang M, Kielstein J, Klostermeier U, Knobloch J, Kuehbacher M, Kunzendorf U, Lehnert H, Manns M, Menne T, Meyer T, Michael C, Münte T, Neumann-Grutzeck C, Nuernberger J, Pavenstaedt H, Ramazan L, Renders L, Repenthin J, Ries W, Rohr A, Rump L, Samuelsson O, Sayk F, Schmidt B, Schnatter S, Schöcklmann H, Schreiber S, von Seydewitz C, Steinhoff J, Stracke S, Suerbaum S, van de Loo A, Vischedyk M, Weissenborn K, Wellhöner P, Wiesner M, Zeissig S, Büning J, Schiffer M, Kuehbacher T
BMJ-BRIT MED J. 2012;345:e4565.

[Diagnosis and treatment of Chlamydia trachomatis infections].
Meyer T
HAUTARZT. 2012;63(1):16-23.

Virus NAT for HIV, HBV, and HCV in Post-Mortal Blood Specimens over 48 h after Death of Infected Patients - First Results.
Meyer T, Polywka S, Wulff B, Edler C, Schröder A, Wilkemeyer I, Kalus U, Pruss A
TRANSFUS MED HEMOTH. 2012;39(6):376-380.

Entecavir plus tenofovir combination as rescue therapy in pre-treated chronic hepatitis B patients: an international multicenter cohort study.
Petersen J, Ratziu V, Buti M, Janssen H, Brown A, Lampertico P, Schollmeyer J, Zoulim F, Wedemeyer H, Sterneck M, Berg T, Sarrazin C, Lütgehetmann M, Buggisch P
J HEPATOL. 2012;56(3):520-526.

New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.
Praekelt U, Kopp P, Rehm K, Linder S, Bate N, Patel B, Debrand E, Manso A, Ross R, Conti F, Zhang M, Harris R, Zent R, Critchley D, Monkley S
EUR J CELL BIOL. 2012;91(3):180-191.

Microbiological analysis of a prospective, randomized, double-blind trial comparing moxifloxacin and clindamycin in the treatment of odontogenic infiltrates and abscesses.
Sobottka I, Wegscheider K, Balzer O, Böger R, Hallier O, Giersdorf I, Streichert T, Haddad M, Platzer U, Cachovan G
ANTIMICROB AGENTS CH. 2012;56(5):2565-2569.

XMRV induces cell migration, cytokine expression and tumor angiogenesis: are 22Rv1 cells a suitable prostate cancer model?
Stieler K, Schumacher U, Horst A, Fischer N
PLOS ONE. 2012;7(7):42321.

The use of sinecatechins (polyphenon E) ointment for treatment of external genital warts.
Stockfleth E, Meyer T
EXPERT OPIN BIOL TH. 2012;12(6):783-793.

Lasp-1 regulates podosome function.
Stölting M, Wiesner C, van Vliet V, Butt E, Pavenstädt H, Linder S, Kremerskothen J
PLOS ONE. 2012;7(4):35340.

Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.
Volz T, Lütgehetmann M, Allweiss L, Warlich M, Bierwolf J, Pollok J, Petersen J, Matthes E, Dandri-Petersen M
ANTIVIR THER. 2012;17(4):623-631.

Differentiation of Streptococcus pneumoniae from nonpneumococcal streptococci of the Streptococcus mitis group by matrix-assisted laser desorption ionization-time of flight mass spectrometry.
Werno A, Christner M, Anderson T, Murdoch D
J CLIN MICROBIOL. 2012;50(9):2863-2867.

Siebenjähriger Patient mit plötzlicher schmerzhafter Entzündung an Unterschenkel und Auge
Werth J, Rohde H, Keserü M, Wagenfeld L, Richard G, Galambos P
OPHTHALMOLOGE. 2012;109(11):1115-8.

Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration.
Xavier C, Rastetter R, Blömacher M, Stumpf M, Himmel M, Morgan R, Fernandez M, Wang C, Osman A, Miyata Y, Gjerset R, Eichinger L, Hofmann A, Linder S, Noegel A, Clemen C
SCI REP-UK. 2012;2:241.

Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs.
Aepfelbacher M, Roppenser B, Hentschke M, Ruckdeschel K
EUR J CELL BIOL. 2011;90(11):951-954.

Isolation, purification, crystallization and preliminary crystallographic studies of a chitinase from Crocus vernus.
Akrem A, Iqbal S, Buck F, Meyer A, Perbandt M, Voelter W, Betzel C
ACTA CRYSTALLOGR F. 2011;67(Pt 3):340-343.

S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection.
Andresen E, Lange C, Strodthoff D, Goldmann T, Fischer N, Sahly H, Branscheid D, Heine H
BMC PULM MED. 2011;11:10.

Purification, crystallization and preliminary X-ray diffraction analysis of the thiaminase type II from Staphylococcus aureus.
Begum A, Drebes J, Perbandt M, Wrenger C, Betzel C
ACTA CRYSTALLOGR F. 2011;67(Pt 1):51-53.

Primary rat hepatocyte culture on 3D nanofibrous polymer scaffolds for toxicology and pharmaceutical research.
Bierwolf J, Lütgehetmann M, Feng K, Erbes J, Deichmann S, Toronyi E, Stieglitz C, Nashan B, Ma P, Pollok J
BIOTECHNOL BIOENG. 2011;108(1):141-150.

Salmonella phage ST64B encodes a member of the SseK/NleB effector family.
Brown N, Coombes B, Bishop J, Wickham M, Lowden M, Gal-Mor O, Goode D, Boyle C, Sanderson K, Finlay B
PLOS ONE. 2011;6(3):17824.

Structure of the Lassa virus nucleoprotein revealed by X-ray crystallography, small-angle X-ray scattering, and electron microscopy.
Brunotte L, Kerber R, Shang W, Hauer F, Hass M, Gabriel M, Lelke M, Busch C, Stark H, Svergun D, Betzel C, Perbandt M, Günther S
J BIOL CHEM. 2011;286(44):38748-38756.

Comparative efficacy and safety of moxifloxacin and clindamycin in the treatment of odontogenic abscesses and inflammatory infiltrates: a phase II, double-blind, randomized trial.
Cachovan G, Böger R, Giersdorf I, Hallier O, Streichert T, Haddad M, Platzer U, Schön G, Wegscheider K, Sobottka I
ANTIMICROB AGENTS CH. 2011;55(3):1142-1147.

The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes.
Cornfine S, Himmel M, Kopp P, El-Azzouzi K, Wiesner C, Krüger M, Rudel T, Linder S
MOL BIOL CELL. 2011;22(2):202-215.

Prevalence of Chlamydia trachomatis among young German adolescents, 2005-06.
Desai S, Meyer T, Thamm M, Hamouda O, Bremer V
SEX HEALTH. 2011;8(1):120-122.

Purification, crystallization and preliminary X-ray diffraction analysis of ThiM from Staphylococcus aureus.
Drebes J, Perbandt M, Wrenger C, Betzel C
ACTA CRYSTALLOGR F. 2011;67(Pt 4):479-481.

The new influenza A (H1N1/09): symptoms, diagnostics, and autopsy results.
Edler C, Klein A, Gehl A, Ilchmann C, Scherpe S, Schrot M
INT J LEGAL MED. 2011;125(2):157-161.

A prospective time-course study on serological testing for human immunodeficiency virus, hepatitis B virus and hepatitis C virus with blood samples taken up to 48 h after death.
Edler C, Wulff B, Schröder A, Wilkemeyer I, Polywka S, Meyer T, Kalus U, Pruss A
J MED MICROBIOL. 2011;60(Pt 7):920-926.

Staphylococcus epidermidis polysaccharide intercellular adhesin activates complement.
Fredheim E, Granslo H, Flægstad T, Figenschau Y, Rohde H, Sadovskaya I, Mollnes T, Klingenberg C
FEMS IMMUNOL MED MIC. 2011;63(2):269-280.

Destabilization of YopE by the Ubiquitin-Proteasome Pathway Fine-Tunes Yop Delivery into Host Cells and Facilitates Systemic Spread of Yersinia enterocolitica in Host Lymphoid Tissue.
Gaus K, Hentschke M, Czymmeck N, Novikova L, Trülzsch K, Valentin-Weigand P, Aepfelbacher M, Ruckdeschel K
INFECT IMMUN. 2011;79(3):1166-1175.

Characterization of Enterobacter cloacae pneumonia: a single-center retrospective analysis.
Hennigs J, Baumann H, Schmiedel S, Tennstedt P, Sobottka I, Bokemeyer C, Kluge S, Klose H
LUNG. 2011;189(6):475-483.

Emergence of carbapenemases in Gram-negative bacteria in Hamburg, Germany.
Hentschke M, Goritzka V, Belmar Campos C, Merkel P, Ilchmann C, Lellek H, Scherpe S, Aepfelbacher M, Rohde H
DIAGN MICR INFEC DIS. 2011;71(3):312-315.

CMY-42, a novel plasmid-mediated CMY-2 variant AmpC beta-lactamase.
Hentschke M, Kotsakis S, Wolters M, Heisig P, Miriagou V, Aepfelbacher M
MICROB DRUG RESIST. 2011;17(2):165-169.

Parvovirus B19 infection and autoimmune hepatitis in a child with sickle cell anemia.
Kordes U, Schneppenheim R, Briem-Richter A, Scherpe S, Schäfer H
PEDIATR BLOOD CANCER. 2011;56(2):323-324.

Zona occludens proteins modulate podosome formation and function.
Kremerskothen J, Stölting M, Wiesner C, Korb-Pap A, van Vliet V, Linder S, Huber T, Rottiers P, Reuzeau E, Genot E, Pavenstädt H
FASEB J. 2011;25(2):505-514.

Degrading devices: invadosomes in proteolytic cell invasion.
Linder S, Wiesner C, Himmel M
ANNU REV CELL DEV BI. 2011;27:185-211.

The structure of the unliganded extracellular domain of the interleukin-6 signal transducer gp130 in solution.
Lorenzen I, Shang W, Perbandt M, Petoukhov M, Svergun D, Waetzig G, Rose-John S, Hilgenfeld R, Grötzinger J
EUR J CELL BIOL. 2011;90(6-7):515-520.

Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.
Lütgehetmann M, Bornscheuer T, Volz T, Allweiss L, Bockmann J, Pollok J, Lohse A, Petersen J, Dandri-Petersen M
GASTROENTEROLOGY. 2011;140(7):1-2, 2074-2083.

Antibody response after a single dose of an AS03-adjuvanted split-virion influenza A (H1N1) vaccine in heart transplant recipients.
Meyer S, Adam M, Schweiger B, Ilchmann C, Zu Eulenburg C, Sattinger E, Runte H, Schlüter M, Deuse T, Reichenspurner H, Costardt-Jäckle A
TRANSPLANTATION. 2011;91(9):1031-1035.

Fortschritte in der Labordiagnostik sexuell übertragbarer Infektionen
Meyer T
HAUTARZT. 2011;62(11):871.

Novel diagnostic methods
Meyer T
2011. Sexually transmitted infections and sexually transmitted diseases. Springer Berlin Heidelberg: 749-773.

Replication, gene expression and particle production by a consensus Merkel Cell Polyomavirus (MCPyV) genome.
Neumann F, Borchert S, Schmidt C, Reimer R, Hohenberg H, Fischer N, Grundhoff A
PLOS ONE. 2011;6(12):29112.

Identification of the Shiga toxin-producing Escherichia coli O104:H4 strain responsible for a food poisoning outbreak in Germany by PCR.
Qin J, Cui Y, Zhao X, Rohde H, Liang T, Wolters M, Li D, Belmar Campos C, Christner M, Song Y, Yang R
J CLIN MICROBIOL. 2011;49(9):3439-3440.

Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4.
Rohde H, Qin J, Cui Y, Li D, Loman N, Hentschke M, Chen W, Pu F, Peng Y, Li J, Xi F, Li S, Li Y, Zhang Z, Yang X, Zhao M, Wang P, Guan Y, Cen Z, Zhao X, Christner M, Kobbe R, Loos S, Oh J, Yang L, Danchin A, Gao G, Song Y, Li Y, Yang H, Wang J, Xu J, Pallen M, Wang J, Aepfelbacher M, Yang R, Consortium E
NEW ENGL J MED. 2011;365(8):718-724.

CcpA coordinates central metabolism and biofilm formation in Staphylococcus epidermidis.
Sadykov M, Hartmann T, Mattes T, Hiatt M, Jann N, Zhu Y, Ledala N, Landmann R, Herrmann M, Rohde H, Bischoff M, Somerville G
MICROBIOLOGY+. 2011;157(Pt 12):3458-3468.

Staphylococcus epidermidis uses distinct mechanisms of biofilm formation to interfere with phagocytosis and activation of mouse macrophage-like cells 774A.1.
Schommer N, Christner M, Hentschke M, Ruckdeschel K, Aepfelbacher M, Rohde H
INFECT IMMUN. 2011;79(6):2267-2276.

Organelle segregation into Plasmodium liver stage merozoites.
Stanway R, Mueller N, Zobiak B, Graewe S, Froehlke U, Zessin P, Aepfelbacher M, Heussler V
CELL MICROBIOL. 2011;13(11):1768-1782.

Epidemic keratoconjunctivitis: the current situation and recommendations for prevention and treatment
Stemplewitz B, Loderstädt U, Richard G, Kaulfers P, Gesser C, Stemplewitz B
DTSCH ARZTEBL INT. 2011;108(27):475-80.

No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe.
Stieler K, Schindler S, Schlomm T, Hohn O, Bannert N, Simon R, Minner S, Schindler M, Fischer N
PLOS ONE. 2011;6(10):25592.

Primary human hepatocytes on biodegradable poly(l-lactic acid) matrices: a promising model for improving transplantation efficiency with tissue engineering.
Török-Pollok E, Lütgehetmann M, Bierwolf J, Melbeck S, Düllmann J, Nashan B, Ma P, Pollok J
LIVER TRANSPLANT. 2011;17(2):104-114.

Invasive aspergillosis caused by Aspergillus terreus in a living donor liver transplant recipient successfully treated by caspofungin.
Walter J, Sobottka I, Rogiers X, Broering D, Fischer L
MYCOSES. 2011;54(4):220-222.

MALDI-TOF MS fingerprinting allows for discrimination of major methicillin-resistant Staphylococcus aureus lineages.
Wolters M, Rohde H, Maier T, Belmar Campos C, Franke G, Scherpe S, Aepfelbacher M, Christner M
INT J MED MICROBIOL. 2011;301(1):64-68.

Stage-specific excretory-secretory small heat shock proteins from the parasitic nematode Strongyloides ratti--putative links to host's intestinal mucosal defense system.
Younis A, Geisinger F, Ajonina-Ekoti I, Soblik H, Steen H, Mitreva M, Erttmann K, Perbandt M, Liebau E, Brattig N
FEBS J. 2011;278(18):3319-3336.

Entecavir treatment for chronic hepatitis B: adaptation is not needed for the majority of naïve patients with a partial virological response
Zoutendijk R, Reijnders J, Brown A, Zoulim F, Mutimer D, Deterding K, Petersen J, Hofmann W, Buti M, Santantonio T, van Bömmel F, Pradat P, Oo Y, Lütgehetmann M, Berg T, Hansen B, Wedemeyer H, Janssen H
HEPATOLOGY. 2011;54(2):443-51.

Lysophosphatidylcholine-mediated functional inactivation of syndecan-4 results in decreased adhesion and motility of dendritic cells.
Bühligen J, Himmel M, Gebhardt C, Simon J, Ziegler W, Averbeck M
J CELL PHYSIOL. 2010;225(3):905-914.

Diagnosis of Toxoplasma gondii infection after allogeneic stem cell transplant can be difficult and requires intensive scrutiny.
Cavattoni I, Ayuketang Ayuk F, Zander A, Zabelina T, Bacher A, Cayiroglu E, Knospe V, Illies T, Aepfelbacher M, Richard G, Kröger N, Bacher U
LEUKEMIA LYMPHOMA. 2010;51(8):1530-1535.

The giant extracellular matrix-binding protein of Staphylococcus epidermidis mediates biofilm accumulation and attachment to fibronectin.
Christner M, Franke G, Schommer N, Wendt U, Wegert K, Pehle P, Kroll G, Schulze C, Buck F, Mack D, Aepfelbacher M, Rohde H
MOL MICROBIOL. 2010;75(1):187-207.

Rapid identification of bacteria from positive blood culture bottles by use of matrix-assisted laser desorption-ionization time of flight mass spectrometry fingerprinting.
Christner M, Rohde H, Wolters M, Sobottka I, Wegscheider K, Aepfelbacher M
J CLIN MICROBIOL. 2010;48(5):1584-1591.

Detection of Merkel cell polyomavirus (MCPyV) in Merkel cell carcinoma cell lines: Cell morphology and growth phenotype do not reflect presence of the virus
Fischer N, Brandner J, Fuchs F, Moll I, Grundhoff A
INT J CANCER. 2010;126(9):2133-2142.

Xenotropic murine leukemia virus-related gammaretrovirus in respiratory tract.
Fischer N, Schulz C, Stieler K, Hohn O, Lange C, Drosten C, Aepfelbacher M
EMERG INFECT DIS. 2010;16(6):1000-1002.

Epidemiology, variable genetic organisation and regulation of the EDIN-B toxin in Staphylococcus aureus from bacteraemic patients.
Franke G, Böckenholt A, Sugai M, Rohde H, Aepfelbacher M
MICROBIOL-SGM. 2010;156:860-872.

Rapid identification of staphylococci from prosthetic joint infections using MALDI-TOF mass-spectrometry.
Harris L, El-Bouri K, Johnston S, Rees E, Frommelt L, Siemssen N, Christner M, Davies A, Rohde H, Mack D
INT J ARTIF ORGANS. 2010;33(9):568-574.

Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation.
Hentschke M, Berneking L, Campos C, Buck F, Ruckdeschel K, Aepfelbacher M
PLOS ONE. 2010;5(10):.

ramR mutations in clinical isolates of Klebsiella pneumoniae with reduced susceptibility to tigecycline.
Hentschke M, Wolters M, Sobottka I, Rohde H, Aepfelbacher M
ANTIMICROB AGENTS CH. 2010;54(6):2720-2723.

Abiotrophia defectiva endophthalmitis with retinal involvement and infiltrative keratitis: case report and review of the literature
Horstkotte M, Dobinsky S, Rohde H, Knobloch J, Hassenstein A, Kalitzky M, Richard G, Linke S
EUR J CLIN MICROBIOL. 2010;29(6):727-731.

Comparison of resistance against erythromycin and moxifloxacin, presence of binary toxin gene and PCR ribotypes in Clostridium difficile isolates from 1990 and 2008.
Ilchmann C, Zaiss N, Speicher A, Christner M, Ackermann G, Rohde H
EUR J CLIN MICROBIOL. 2010;29(12):1571-1573.

The 3-ureidopropionase of Caenorhabditis elegans, an enzyme involved in pyrimidine degradation.
Janowitz T, Ajonina I, Perbandt M, Woltersdorf C, Hertel P, Liebau E, Gigengack U
FEBS J. 2010;277(19):4100-4109.

Patienten mit Problemkeimen
Kampe K, Sobottka I, Kluge S
Intensivmed up2date. 2010;6(3):181-201.

Transparent peer review--an appreciation of the reviewers' contribution to a published article.
Linder S, Schliwa M, Werner S, Gebauer D
EUR J CELL BIOL. 2010;89(11):779.

Wissensstand, Präventionsverhalten und Therapieadhärenz von Patienten mit chronischer Hepatitis B in einem großen tertiären Zentrum in Deutschland
Lutgehetmann M, Meyer F, Volz T, Lohse A, Fischer C, Dandri M, Petersen J
Z GASTROENTEROL. 2010;48(9):1126-32.

Elevated serum levels of interleukin-10 and tumor necrosis factor α [corrected] are both associated with vital exhaustion in patients with cardiovascular risk factors
Meyer T, Stanske B, Kochen M, Cordes A, Yüksel I, Wachter R, Lüers C, Scherer M, Binder L, Pieske B, Herrmann-Lingen C
PSYCHOSOMATICS. 2010;51(3):248-56.

Selection and counterselection of the rtI233V adefovir resistance mutation during antiviral therapy.
Schildgen O, Olotu C, Funk A, Zöllner B, Helm M, Rockstroh J, Sirma H
J CLIN MICROBIOL. 2010;48(2):631-634.

Genomic Tandem Repeat Analysis Proves Laboratory-Acquired Brucellosis in Veterinary (Camel) Diagnostic Laboratory in the United Arab Emirates.
Schulze Zur Wiesch J, Wichmann D, Sobottka I, Rohde H, Schmoock G, Wernery R, Schmiedel S, Burchard G, Melzer F
ZOONOSES PUBLIC HLTH. 2010;57(5):315-317.

Apobec 3G efficiently reduces infectivity of the human exogenous gammaretrovirus XMRV.
Stieler K, Fischer N
PLOS ONE. 2010;5(7):11738.

Host range and cellular tropism of the human exogenous gammaretrovirus XMRV.
Stieler K, Schulz C, Lavanya M, Aepfelbacher M, Stocking C, Fischer N
VIROLOGY. 2010;399(1):23-30.

KIF5B and KIF3A/KIF3B kinesins drive MT1-MMP surface exposure, CD44 shedding, and extracellular matrix degradation in primary macrophages.
Wiesner C, Faix J, Himmel M, Bentzien F, Linder S
BLOOD. 2010;116(9):1559-1569.

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